| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | MERTK | MERTK_HUMAN | 5K0KA | Q12866 | 577 | 863 | 999.0 | 6Q1:904 | Type1 | Inactive | DFGin | 6.0432 | 13.0832 | BLBplus | -151.37, 176.9 | 70.65, 6.45 | -74.59, 148.34 | 49.33, 80.56 | 71.75, 161.84 | out-out | out | 13.2061 | Saltbr-out | 9.6637 | HRD-in | -93.56, -51.52 | 71.26, 5.04 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 31.89 | APE8-rot-na | 27.0 | APE67-dihe-in | -74.95, 2.1 | -52.33, -38.07 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.545 | 0.203 | 0.254 | A | 313.0 | 260.0 | 27 | 30 | 12 | 18 | [[587, 856]] | 1.0 | 5k0k | TYR_MERTK_HUMAN | TYR | 1.4e-92 | 315.6 | 2.0 | 261.0 | 260.0 | 740 | 741 | 742 | 744 | 746 | 619 | 637 | 641 | 720 | 722 | 721 | 723.0 | 782 | 770 | 765 | 764 | 763 | 762 | 761 | 760 | 759 | 672 | Tyrosine-protein kinase Mer |
| TYR | MERTK | MERTK_HUMAN | 5K0KB | Q12866 | 577 | 862 | 999.0 | 6Q1:904 | Type1 | Inactive | DFGin | 6.1892 | 13.3888 | None | -144.02, -179.34 | 56.66, 60.57 | -135.11, 999.0 | 52.83, 74.37 | 999.0, 999.0 | out-out | out | 12.8302 | Saltbr-out | 9.0057 | HRD-in | -81.18, -49.68 | 74.51, -7.68 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 34.62 | APE8-rot-na | 27.52 | APE67-dihe-in | -73.94, -3.99 | -57.79, -40.89 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.545 | 0.203 | 0.254 | B | 313.0 | 248.0 | 38 | 30 | 10 | 20 | [[587, 856]] | 1.0 | 5k0k | TYR_MERTK_HUMAN | TYR | 1.4e-92 | 315.6 | 2.0 | 261.0 | 260.0 | 740 | 741 | 742 | 744 | 746 | 619 | 637 | 641 | 720 | 722 | 721 | 723.0 | 782 | 770 | 765 | 764 | 763 | 762 | 761 | 760 | 759 | 672 | Tyrosine-protein kinase Mer |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | MERTK | MERTK_HUMAN | 5K0KA | Q12866 | 577 | 863 | 999.0 | 6Q1:904 | Type1 | Inactive | DFGin | 6.0432 | 13.0832 | BLBplus | -151.37, 176.9 | 70.65, 6.45 | -74.59, 148.34 | 49.33, 80.56 | 71.75, 161.84 | out-out | out | 13.2061 | Saltbr-out | 9.6637 | HRD-in | -93.56, -51.52 | 71.26, 5.04 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 31.89 | APE8-rot-na | 27.0 | APE67-dihe-in | -74.95, 2.1 | -52.33, -38.07 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.545 | 0.203 | 0.254 | A | 313.0 | 260.0 | 27 | 30 | 12 | 18 | [[587, 856]] | 1.0 | 5k0k | Homo sapiens | TYR_MERTK_HUMAN | TYR | 1.4e-92 | 315.6 | 2.0 | 261.0 | 260.0 | 740 | 741 | 742 | 744 | 746 | 619 | 637 | 641 | 720 | 722 | 721 | 723.0 | 782 | 770 | 765 | 764 | 763 | 762 | 761 | 760 | 759 | 672 | Tyrosine-protein kinase Mer |
| TYR | MERTK | MERTK_HUMAN | 5K0KB | Q12866 | 577 | 862 | 999.0 | 6Q1:904 | Type1 | Inactive | DFGin | 6.1892 | 13.3888 | None | -144.02, -179.34 | 56.66, 60.57 | -135.11, 999.0 | 52.83, 74.37 | 999.0, 999.0 | out-out | out | 12.8302 | Saltbr-out | 9.0057 | HRD-in | -81.18, -49.68 | 74.51, -7.68 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 34.62 | APE8-rot-na | 27.52 | APE67-dihe-in | -73.94, -3.99 | -57.79, -40.89 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.545 | 0.203 | 0.254 | B | 313.0 | 248.0 | 38 | 30 | 10 | 20 | [[587, 856]] | 1.0 | 5k0k | Homo sapiens | TYR_MERTK_HUMAN | TYR | 1.4e-92 | 315.6 | 2.0 | 261.0 | 260.0 | 740 | 741 | 742 | 744 | 746 | 619 | 637 | 641 | 720 | 722 | 721 | 723.0 | 782 | 770 | 765 | 764 | 763 | 762 | 761 | 760 | 759 | 672 | Tyrosine-protein kinase Mer |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|