PDB: 4U9A — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4U9AA
DFGin None 1 50.0% 4U9AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 4U9AA Q9NWZ3 166 458 460.0 STU:501 Type1 None DFGin 7.0448 14.9069 BLAminus -101.08, -157.39 29.3, 88.18 -95.05, 25.51 282.71, 82.79 -64.14, 4.87 in-in in 8.9978 Saltbr-in 3.2256 HRD-in -68.43, -44.05 62.5, 13.64 in-none-in SNCini none-in ActLoopNT-none 999.0 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.36, 146.03 APE9-dihe-na 162.68, -156.1 APE8-dihe-in -121.4, 112.37 APE8-rot-in 316.45 APE67-dihe-in -59.48, -18.83 -58.3, -38.15 APE12-dist-in 9.9834 APE11-dist-in 11.9507 APE10-dist-in 7.2186 APE9-dist-in 3.878 D311N None None XRAY 2.8 0.185 0.24 A 312.0 272.0 21 30 22 8 [[183, 456]] 1.0 4u9a TKL_IRAK4_HUMAN TKL 3e-83 285.4 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U9AB Q9NWZ3 166 458 460.0 STU:501 Type1 Inactive DFGin 5.6327 14.406 None -136.0, 173.79 77.97, 80.6 -165.88, 999.0 67.94, 103.04 999.0, 999.0 in-in in 9.4018 Saltbr-in 2.9242 HRD-in -69.54, -47.75 75.57, 5.12 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na -138.84, -18.64 APE9-dihe-na -63.49, 153.65 APE8-dihe-in -64.27, 92.38 APE8-rot-in 304.32 APE67-dihe-in -63.41, -26.11 -54.68, -17.6 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.3588 D311N None None XRAY 2.8 0.185 0.24 B 312.0 270.0 23 30 18 12 [[183, 456]] 1.0 4u9a TKL_IRAK4_HUMAN TKL 3e-83 285.4 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 4U9A — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4U9AA
DFGin None 1 50.0% 4U9AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 4U9AA Q9NWZ3 166 458 460.0 STU:501 Type1 None DFGin 7.0448 14.9069 BLAminus -101.08, -157.39 29.3, 88.18 -95.05, 25.51 282.71, 82.79 -64.14, 4.87 in-in in 8.9978 Saltbr-in 3.2256 HRD-in -68.43, -44.05 62.5, 13.64 in-none-in SNCini none-in ActLoopNT-none 999.0 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.36, 146.03 APE9-dihe-na 162.68, -156.1 APE8-dihe-in -121.4, 112.37 APE8-rot-in 316.45 APE67-dihe-in -59.48, -18.83 -58.3, -38.15 APE12-dist-in 9.9834 APE11-dist-in 11.9507 APE10-dist-in 7.2186 APE9-dist-in 3.878 D311N None None XRAY 2.8 0.185 0.24 A 312.0 272.0 21 30 22 8 [[183, 456]] 1.0 4u9a Homo sapiens TKL_IRAK4_HUMAN TKL 3e-83 285.4 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U9AB Q9NWZ3 166 458 460.0 STU:501 Type1 Inactive DFGin 5.6327 14.406 None -136.0, 173.79 77.97, 80.6 -165.88, 999.0 67.94, 103.04 999.0, 999.0 in-in in 9.4018 Saltbr-in 2.9242 HRD-in -69.54, -47.75 75.57, 5.12 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na -138.84, -18.64 APE9-dihe-na -63.49, 153.65 APE8-dihe-in -64.27, 92.38 APE8-rot-in 304.32 APE67-dihe-in -63.41, -26.11 -54.68, -17.6 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.3588 D311N None None XRAY 2.8 0.185 0.24 B 312.0 270.0 23 30 18 12 [[183, 456]] 1.0 4u9a Homo sapiens TKL_IRAK4_HUMAN TKL 3e-83 285.4 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 4U9A — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name