PDB: 4RIX — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIXC
DFGin None 2 50.0% 4RIXD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIXB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.919 14.579 None -139.87, -153.46 71.8, -106.42 74.55, 12.91 300.13, 117.16 -73.01, -18.89 in-in in 8.778 Saltbr-in 2.851 HRD-out -79.93, 91.22 -73.37, 9.67 in-in-none SNCiin in-none ActLoopNT-in 2.815 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.04 APE8-dihe-in -57.54, 105.82 APE8-rot-na 336.15 APE67-dihe-in -83.65, 5.55 -71.82, -34.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.644 V948R,F997A,L1001A None None XRAY 3.1 0.21 0.258 B 345 293 4 0 0 4 [[712, 970]] 1.0 4rix TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIXD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.984 14.396 None -138.76, -155.76 70.86, -102.17 73.98, 14.44 299.1, 114.44 -71.0, -18.03 in-in in 8.433 Saltbr-in 2.13 HRD-in -75.74, -46.31 59.89, 5.04 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.43, 115.77 APE9-dihe-in -128.43, 136.25 APE8-dihe-in -57.6, 106.59 APE8-rot-na 335.5 APE67-dihe-in -81.04, 4.3 -70.58, -32.32 APE12-dist-na 11.336 APE11-dist-na 10.144 APE10-dist-na 10.428 APE9-dist-in 5.987 V948R,F997A,L1001A None None XRAY 3.1 0.21 0.258 D 345 297 0 0 0 0 [[712, 970]] 1.0 4rix TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIXA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.534 12.788 BLBplus -125.2, 170.11 60.89, 28.84 -82.14, 140.77 56.51, 90.87 77.72, -6.25 out-na out 15.04 Saltbr-na 999.0 HRD-in -77.1, -53.12 66.52, 0.72 na-out-none SNCaon out-none ActLoopNT-out 6.513 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -5.5 APE8-rot-na 30.9 APE67-dihe-in -82.84, -10.3 -67.07, -25.63 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 Q809R None None XRAY 3.1 0.21 0.258 A 326 269 12 0 0 12 [[709, 967]] 1.0 4rix TYR_ERBB3_HUMAN TYR 9.7e-80 273.5 2 260 259 851 852 853 855 857 742 759 763 831 833 832 834 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.557 13.116 BLBplus -126.64, 170.72 61.2, 28.92 -82.69, 140.73 56.76, 91.32 77.44, -6.2 out-na out 15.473 Saltbr-na 999.0 HRD-in -76.48, -52.61 66.58, -0.13 na-out-out SNCaoo out-out ActLoopNT-out 6.372 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -112.15, 5.58 APE9-dihe-in -58.87, 135.06 APE8-dihe-out -71.85, -6.39 APE8-rot-na 348.17 APE67-dihe-in -82.4, -10.58 -67.81, -25.66 APE12-dist-na 21.658 APE11-dist-na 20.612 APE10-dist-na 15.605 APE9-dist-out 9.969 Q809R None None XRAY 3.1 0.21 0.258 C 326 275 6 0 0 0 [[709, 967]] 1.0 4rix TYR_ERBB3_HUMAN TYR 9.7e-80 273.5 2 260 259 851 852 853 855 857 742 759 763 831 833 832 834 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIX — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIXC
DFGin None 2 50.0% 4RIXD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIXB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.919 14.579 None -139.87, -153.46 71.8, -106.42 74.55, 12.91 300.13, 117.16 -73.01, -18.89 in-in in 8.778 Saltbr-in 2.851 HRD-out -79.93, 91.22 -73.37, 9.67 in-in-none SNCiin in-none ActLoopNT-in 2.815 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.04 APE8-dihe-in -57.54, 105.82 APE8-rot-na 336.15 APE67-dihe-in -83.65, 5.55 -71.82, -34.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.644 V948R,F997A,L1001A None None XRAY 3.1 0.21 0.258 B 345 293 4 0 0 4 [[712, 970]] 1.0 4rix Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIXD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.984 14.396 None -138.76, -155.76 70.86, -102.17 73.98, 14.44 299.1, 114.44 -71.0, -18.03 in-in in 8.433 Saltbr-in 2.13 HRD-in -75.74, -46.31 59.89, 5.04 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.43, 115.77 APE9-dihe-in -128.43, 136.25 APE8-dihe-in -57.6, 106.59 APE8-rot-na 335.5 APE67-dihe-in -81.04, 4.3 -70.58, -32.32 APE12-dist-na 11.336 APE11-dist-na 10.144 APE10-dist-na 10.428 APE9-dist-in 5.987 V948R,F997A,L1001A None None XRAY 3.1 0.21 0.258 D 345 297 0 0 0 0 [[712, 970]] 1.0 4rix Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIXA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.534 12.788 BLBplus -125.2, 170.11 60.89, 28.84 -82.14, 140.77 56.51, 90.87 77.72, -6.25 out-na out 15.04 Saltbr-na 999.0 HRD-in -77.1, -53.12 66.52, 0.72 na-out-none SNCaon out-none ActLoopNT-out 6.513 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -5.5 APE8-rot-na 30.9 APE67-dihe-in -82.84, -10.3 -67.07, -25.63 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 Q809R None None XRAY 3.1 0.21 0.258 A 326 269 12 0 0 12 [[709, 967]] 1.0 4rix Homo sapiens TYR_ERBB3_HUMAN TYR 9.7e-80 273.5 2 260 259 851 852 853 855 857 742 759 763 831 833 832 834 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.557 13.116 BLBplus -126.64, 170.72 61.2, 28.92 -82.69, 140.73 56.76, 91.32 77.44, -6.2 out-na out 15.473 Saltbr-na 999.0 HRD-in -76.48, -52.61 66.58, -0.13 na-out-out SNCaoo out-out ActLoopNT-out 6.372 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -112.15, 5.58 APE9-dihe-in -58.87, 135.06 APE8-dihe-out -71.85, -6.39 APE8-rot-na 348.17 APE67-dihe-in -82.4, -10.58 -67.81, -25.66 APE12-dist-na 21.658 APE11-dist-na 20.612 APE10-dist-na 15.605 APE9-dist-out 9.969 Q809R None None XRAY 3.1 0.21 0.258 C 326 275 6 0 0 0 [[709, 967]] 1.0 4rix Homo sapiens TYR_ERBB3_HUMAN TYR 9.7e-80 273.5 2 260 259 851 852 853 855 857 742 759 763 831 833 832 834 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIX — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name