PDB: 4RIW — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIWC
DFGin None 2 50.0% 4RIWD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIWB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.9474 14.5093 None -144.94, -140.84 60.54, -94.56 67.75, 16.38 293.55, 125.63 -72.75, -24.64 in-in in 8.962 Saltbr-in 2.5768 HRD-out -81.5, 87.13 -71.92, 10.44 in-in-none SNCiin in-none ActLoopNT-in 2.9141 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.11 APE8-dihe-in -64.72, 105.47 APE8-rot-na 338.81 APE67-dihe-in -78.09, 0.73 -66.98, -35.92 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.3389 V948R,F997A,L1001A None None XRAY 3.1 0.233 0.287 B 345.0 293.0 4 30 26 4 [[712, 970]] 1.0 4riw TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIWD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 6.0156 14.3995 None -147.43, -141.55 60.24, -94.38 68.1, 17.38 294.17, 126.48 -72.23, -23.22 in-in in 8.8454 Saltbr-in 3.0814 HRD-in -78.23, -46.1 60.09, 5.38 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -105.64, 111.47 APE9-dihe-in -129.74, 134.09 APE8-dihe-in -62.84, 106.17 APE8-rot-na 337.89 APE67-dihe-in -78.37, 3.33 -65.15, -34.97 APE12-dist-na 11.3973 APE11-dist-na 9.9458 APE10-dist-na 9.7227 APE9-dist-in 6.0148 V948R,F997A,L1001A None None XRAY 3.1 0.233 0.287 D 345.0 297.0 0 30 30 0 [[712, 970]] 1.0 4riw TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIWA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.6652 12.9195 BLBplus -124.68, 170.7 61.91, 32.93 -86.72, 138.2 53.99, 90.7 80.0, -6.46 out-na out 15.1205 Saltbr-na 999.0 HRD-in -76.0, -53.69 67.87, 2.11 na-out-none SNCaon out-none ActLoopNT-out 6.6323 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -2.58 APE8-rot-na 28.66 APE67-dihe-in -88.2, -5.19 -70.28, -23.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 3.1 0.233 0.287 A 326.0 269.0 12 30 18 12 [[709, 967]] 1.0 4riw TYR_ERBB3_HUMAN TYR 6.1e-80 274.2 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.6184 13.0319 BLBplus -125.06, 170.64 62.1, 33.09 -86.97, 138.33 54.47, 90.5 80.01, -6.38 out-na out 15.4904 Saltbr-na 999.0 HRD-in -75.9, -53.21 67.39, 0.69 na-out-out SNCaoo out-out ActLoopNT-out 6.3934 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -113.39, 20.05 APE9-dihe-in -68.39, 127.6 APE8-dihe-out -63.99, -4.42 APE8-rot-na 333.17 APE67-dihe-in -86.76, -6.22 -71.15, -22.24 APE12-dist-na 21.5437 APE11-dist-na 20.4194 APE10-dist-na 15.4077 APE9-dist-out 10.083 None None None XRAY 3.1 0.233 0.287 C 326.0 275.0 6 30 30 0 [[709, 967]] 1.0 4riw TYR_ERBB3_HUMAN TYR 6.1e-80 274.2 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIW — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIWC
DFGin None 2 50.0% 4RIWD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIWB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.9474 14.5093 None -144.94, -140.84 60.54, -94.56 67.75, 16.38 293.55, 125.63 -72.75, -24.64 in-in in 8.962 Saltbr-in 2.5768 HRD-out -81.5, 87.13 -71.92, 10.44 in-in-none SNCiin in-none ActLoopNT-in 2.9141 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.11 APE8-dihe-in -64.72, 105.47 APE8-rot-na 338.81 APE67-dihe-in -78.09, 0.73 -66.98, -35.92 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.3389 V948R,F997A,L1001A None None XRAY 3.1 0.233 0.287 B 345.0 293.0 4 30 26 4 [[712, 970]] 1.0 4riw Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIWD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 6.0156 14.3995 None -147.43, -141.55 60.24, -94.38 68.1, 17.38 294.17, 126.48 -72.23, -23.22 in-in in 8.8454 Saltbr-in 3.0814 HRD-in -78.23, -46.1 60.09, 5.38 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -105.64, 111.47 APE9-dihe-in -129.74, 134.09 APE8-dihe-in -62.84, 106.17 APE8-rot-na 337.89 APE67-dihe-in -78.37, 3.33 -65.15, -34.97 APE12-dist-na 11.3973 APE11-dist-na 9.9458 APE10-dist-na 9.7227 APE9-dist-in 6.0148 V948R,F997A,L1001A None None XRAY 3.1 0.233 0.287 D 345.0 297.0 0 30 30 0 [[712, 970]] 1.0 4riw Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIWA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.6652 12.9195 BLBplus -124.68, 170.7 61.91, 32.93 -86.72, 138.2 53.99, 90.7 80.0, -6.46 out-na out 15.1205 Saltbr-na 999.0 HRD-in -76.0, -53.69 67.87, 2.11 na-out-none SNCaon out-none ActLoopNT-out 6.6323 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -2.58 APE8-rot-na 28.66 APE67-dihe-in -88.2, -5.19 -70.28, -23.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 3.1 0.233 0.287 A 326.0 269.0 12 30 18 12 [[709, 967]] 1.0 4riw Homo sapiens TYR_ERBB3_HUMAN TYR 6.1e-80 274.2 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.6184 13.0319 BLBplus -125.06, 170.64 62.1, 33.09 -86.97, 138.33 54.47, 90.5 80.01, -6.38 out-na out 15.4904 Saltbr-na 999.0 HRD-in -75.9, -53.21 67.39, 0.69 na-out-out SNCaoo out-out ActLoopNT-out 6.3934 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -113.39, 20.05 APE9-dihe-in -68.39, 127.6 APE8-dihe-out -63.99, -4.42 APE8-rot-na 333.17 APE67-dihe-in -86.76, -6.22 -71.15, -22.24 APE12-dist-na 21.5437 APE11-dist-na 20.4194 APE10-dist-na 15.4077 APE9-dist-out 10.083 None None None XRAY 3.1 0.233 0.287 C 326.0 275.0 6 30 30 0 [[709, 967]] 1.0 4riw Homo sapiens TYR_ERBB3_HUMAN TYR 6.1e-80 274.2 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIW — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name