PDB: 4MF0 — TYR ITK_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 4MF0A
DFGin None 1 50.0% 4MF0B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR ITK ITK_HUMAN 4MF0A 2.67 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 29Z Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4MF0B 2.67 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 29Z Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK

PDB: 4MF0 — TYR ITK_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 4MF0A
DFGin None 1 50.0% 4MF0B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR ITK ITK_HUMAN 4MF0A 2.67 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 29Z Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4MF0B 2.67 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 29Z Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens

PDB: 4MF0 — TYR ITK_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism