PDB: 4G5P — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4G5PA
DFGinter None 1 50.0% 4G5PB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 4G5PA 3.17 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0WN Type1 696 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4G5PB 3.17 Inactive DFGinter‑None in-in out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 697 - 1018 0 None T790M Epidermal growth factor receptor

PDB: 4G5P — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4G5PA
DFGinter None 1 50.0% 4G5PB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 4G5PA 3.17 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0WN Type1 696 - 1016 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4G5PB 3.17 Inactive DFGinter‑None in-in out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 697 - 1018 0 None T790M Epidermal growth factor receptor Homo sapiens

PDB: 4G5P — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism