PDB: 3LW0 — TYR IGF1R_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 75.0% 3LW0A
DFGout None 1 25.0% 3LW0D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR IGF1R IGF1R_HUMAN 3LW0A P08069 983 1286 1367.0 CCX:1,CCX:1287 Type3,Allosteric Inactive DFGout 14.069 6.9485 BBAminus 170.04, 149.43 -168.43, 165.06 -107.76, 13.31 308.93, 125.37 90.3, 111.78 in-out in 9.1113 Saltbr-out 3.8543 HRD-in -70.2, -51.48 79.95, -15.38 out-out-in SNCooi out-in ActLoopNT-out 18.4556 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.1, 127.88 APE9-dihe-in -120.17, 130.79 APE8-dihe-in -79.59, 68.17 APE8-rot-na 29.74 APE67-dihe-in -72.92, -7.93 -60.62, -32.58 APE12-dist-na 999.0 APE11-dist-na 13.8436 APE10-dist-na 9.4476 APE9-dist-in 7.2938 E1097A,E1099A None None XRAY 1.79 0.157 0.185 A 304.0 292.0 12 30 27 3 [[999, 1268]] 1.0 3lw0 TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0B P08069 983 1286 1367.0 CCX:2,CCX:1287 Type3,Allosteric Inactive DFGout 14.1101 6.9733 BBAminus 170.42, 151.14 -165.86, 166.3 -107.53, 14.79 308.98, 126.2 88.83, 109.35 in-out in 9.031 Saltbr-out 3.8521 HRD-in -73.16, -50.06 79.09, -12.99 out-out-in SNCooi out-in ActLoopNT-out 18.4414 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.78, 129.68 APE9-dihe-in -120.1, 131.04 APE8-dihe-in -81.08, 67.52 APE8-rot-na 31.55 APE67-dihe-in -72.5, -8.7 -59.87, -33.5 APE12-dist-na 999.0 APE11-dist-na 13.7166 APE10-dist-na 9.3879 APE9-dist-in 7.263 E1097A,E1099A None None XRAY 1.79 0.157 0.185 B 304.0 292.0 12 30 27 3 [[999, 1268]] 1.0 3lw0 TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0C P08069 983 1286 1367.0 CCX:3,CCX:1287 Type3,Allosteric Inactive DFGout 14.1381 6.9566 BBAminus 171.38, 152.6 -167.31, 165.1 -107.82, 15.64 311.4, 121.85 88.58, 109.58 in-out in 9.1034 Saltbr-out 3.9218 HRD-in -69.69, -49.88 78.11, -14.34 out-out-in SNCooi out-in ActLoopNT-out 18.4168 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.78, 130.13 APE9-dihe-in -121.41, 130.52 APE8-dihe-in -80.7, 68.48 APE8-rot-na 32.26 APE67-dihe-in -71.62, -8.72 -57.24, -35.28 APE12-dist-na 999.0 APE11-dist-na 13.8448 APE10-dist-na 9.5099 APE9-dist-in 7.2699 E1097A,E1099A None None XRAY 1.79 0.157 0.185 C 304.0 292.0 12 30 27 3 [[999, 1268]] 1.0 3lw0 TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0D P08069 983 1286 1367.0 CCX:4,CCX:1287 Type3,Allosteric Inactive DFGout 14.05 6.8781 None 167.75, 151.96 -167.74, 166.55 -109.76, 14.11 305.35, 128.19 89.26, 110.63 in-out in 9.2241 Saltbr-out 4.213 HRD-in -71.95, -49.8 77.64, -11.7 out-out-in SNCooi out-in ActLoopNT-out 18.495 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.75, 129.65 APE9-dihe-in -120.75, 130.34 APE8-dihe-in -80.64, 68.25 APE8-rot-na 34.21 APE67-dihe-in -72.08, -8.31 -58.75, -34.0 APE12-dist-na 999.0 APE11-dist-na 13.8091 APE10-dist-na 9.4572 APE9-dist-in 7.2497 E1097A,E1099A None None XRAY 1.79 0.157 0.185 D 304.0 292.0 12 30 27 3 [[999, 1268]] 1.0 3lw0 TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

PDB: 3LW0 — TYR IGF1R_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 75.0% 3LW0A
DFGout None 1 25.0% 3LW0D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR IGF1R IGF1R_HUMAN 3LW0A P08069 983 1286 1367.0 CCX:1,CCX:1287 Type3,Allosteric Inactive DFGout 14.069 6.9485 BBAminus 170.04, 149.43 -168.43, 165.06 -107.76, 13.31 308.93, 125.37 90.3, 111.78 in-out in 9.1113 Saltbr-out 3.8543 HRD-in -70.2, -51.48 79.95, -15.38 out-out-in SNCooi out-in ActLoopNT-out 18.4556 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.1, 127.88 APE9-dihe-in -120.17, 130.79 APE8-dihe-in -79.59, 68.17 APE8-rot-na 29.74 APE67-dihe-in -72.92, -7.93 -60.62, -32.58 APE12-dist-na 999.0 APE11-dist-na 13.8436 APE10-dist-na 9.4476 APE9-dist-in 7.2938 E1097A,E1099A None None XRAY 1.79 0.157 0.185 A 304.0 292.0 12 30 27 3 [[999, 1268]] 1.0 3lw0 Homo sapiens TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0B P08069 983 1286 1367.0 CCX:2,CCX:1287 Type3,Allosteric Inactive DFGout 14.1101 6.9733 BBAminus 170.42, 151.14 -165.86, 166.3 -107.53, 14.79 308.98, 126.2 88.83, 109.35 in-out in 9.031 Saltbr-out 3.8521 HRD-in -73.16, -50.06 79.09, -12.99 out-out-in SNCooi out-in ActLoopNT-out 18.4414 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.78, 129.68 APE9-dihe-in -120.1, 131.04 APE8-dihe-in -81.08, 67.52 APE8-rot-na 31.55 APE67-dihe-in -72.5, -8.7 -59.87, -33.5 APE12-dist-na 999.0 APE11-dist-na 13.7166 APE10-dist-na 9.3879 APE9-dist-in 7.263 E1097A,E1099A None None XRAY 1.79 0.157 0.185 B 304.0 292.0 12 30 27 3 [[999, 1268]] 1.0 3lw0 Homo sapiens TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0C P08069 983 1286 1367.0 CCX:3,CCX:1287 Type3,Allosteric Inactive DFGout 14.1381 6.9566 BBAminus 171.38, 152.6 -167.31, 165.1 -107.82, 15.64 311.4, 121.85 88.58, 109.58 in-out in 9.1034 Saltbr-out 3.9218 HRD-in -69.69, -49.88 78.11, -14.34 out-out-in SNCooi out-in ActLoopNT-out 18.4168 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.78, 130.13 APE9-dihe-in -121.41, 130.52 APE8-dihe-in -80.7, 68.48 APE8-rot-na 32.26 APE67-dihe-in -71.62, -8.72 -57.24, -35.28 APE12-dist-na 999.0 APE11-dist-na 13.8448 APE10-dist-na 9.5099 APE9-dist-in 7.2699 E1097A,E1099A None None XRAY 1.79 0.157 0.185 C 304.0 292.0 12 30 27 3 [[999, 1268]] 1.0 3lw0 Homo sapiens TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0D P08069 983 1286 1367.0 CCX:4,CCX:1287 Type3,Allosteric Inactive DFGout 14.05 6.8781 None 167.75, 151.96 -167.74, 166.55 -109.76, 14.11 305.35, 128.19 89.26, 110.63 in-out in 9.2241 Saltbr-out 4.213 HRD-in -71.95, -49.8 77.64, -11.7 out-out-in SNCooi out-in ActLoopNT-out 18.495 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.75, 129.65 APE9-dihe-in -120.75, 130.34 APE8-dihe-in -80.64, 68.25 APE8-rot-na 34.21 APE67-dihe-in -72.08, -8.31 -58.75, -34.0 APE12-dist-na 999.0 APE11-dist-na 13.8091 APE10-dist-na 9.4572 APE9-dist-in 7.2497 E1097A,E1099A None None XRAY 1.79 0.157 0.185 D 304.0 292.0 12 30 27 3 [[999, 1268]] 1.0 3lw0 Homo sapiens TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

PDB: 3LW0 — TYR IGF1R_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name