3IEC

MARK2 (Serine/threonine-protein kinase MARK2)
Group: CAMK
Uniprot: MARK2_HUMAN
Organism: Homo sapiens
Domain boundary: 53 - 304
Resolu: 2.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-in No_ligand No_ligand 49 - 363 0
B Inactive DFGin ABAminus out-out in-in No_ligand No_ligand 49 - 363 0
C Inactive DFGin BLAminus out-out in-in No_ligand No_ligand 49 - 363 0
D Inactive DFGin ABAminus out-in in-in No_ligand No_ligand 49 - 363 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        54         64         74         84 
madlHIGNYR LLKTIGkgnf AKVKLARHIL TGKEVAVKII 
        94        104        114        124 
DKTQLNSSSL QKLFREVRIM KVLNHPNIVK LFEVIETEKT 
       134        144        154        164 
LYLVMEYASG GEVFDYLVAH GWMKEKEARA KFRQIVSAVQ 
       174        184        194        204 
YCHQKFIVHR DLKAENLLLD ADMNIKIADF GFSNEFTFGN 
       214        224        234        244 
KLDTFCGSPP YAAPELFQGK KYDGPEVDVW SLGVILYTLV 
       254        264        274        284 
SGSLPFDGQN LKELRERVLR GKYRIPFYMS TDCENLLKKF 
       294        304        314        324 
LILNPSKRGT LEQIMKDRWM NVGHEDDELK PYVEPLPDYK 
       334        344        354 
DPRRTELMVS MGYTREEIQD SLVGQRYNEV MATYLLLGY
Lower-case residues are disordered in structure.
Mutations: R146W
Phosphorylation: None