PDB: 2ZM3 — TYR IGF1R_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 2ZM3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR IGF1R IGF1R_HUMAN 2ZM3A P08069 981 1285 1367.0 575:60001 Type1 Inactive DFGin 6.7889 15.5048 ABAminus -126.6, 3.02 -143.72, 130.04 -129.16, 19.26 296.34, 90.11 -55.9, -25.14 in-out in 9.5268 Saltbr-out 4.8517 HRD-in -72.76, -50.33 77.45, -5.62 out-in-out SNCoio in-out ActLoopNT-in 3.0484 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -118.76, 9.6 APE9-dihe-in -63.6, 138.6 APE8-dihe-in -67.76, 134.68 APE8-rot-na 23.16 APE67-dihe-in -69.69, -0.78 -61.9, -34.84 APE12-dist-na 13.6449 APE11-dist-na 9.8476 APE10-dist-na 9.2254 APE9-dist-in 5.6449 None PTR1161,PTR1165,PTR1166 PTR1161,PTR1165,PTR1166 XRAY 2.5 0.204 0.257 A 308.0 302.0 3 30 30 0 [[999, 1268]] 1.0 2zm3 TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3B P08069 981 1285 1367.0 575:60001 Type1 Inactive DFGin 6.8979 15.5416 ABAminus -122.17, -30.49 -117.45, 117.57 -113.54, 25.96 293.65, 87.06 -63.47, -21.66 in-out in 9.2709 Saltbr-out 4.7216 HRD-in -70.83, -52.07 75.8, -5.9 out-in-out SNCoio in-out ActLoopNT-in 2.9033 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -116.67, 22.47 APE9-dihe-in -72.91, 143.81 APE8-dihe-in -66.5, 133.93 APE8-rot-na 346.04 APE67-dihe-in -76.24, -7.5 -59.54, -34.53 APE12-dist-na 13.4734 APE11-dist-na 9.742 APE10-dist-na 9.3631 APE9-dist-in 5.8675 None PTR1161,PTR1165,PTR1166 PTR1161,PTR1165,PTR1166 XRAY 2.5 0.204 0.257 B 308.0 298.0 7 30 30 0 [[999, 1268]] 1.0 2zm3 TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3C P08069 981 1285 1367.0 575:60001 Type1 Inactive DFGin 6.947 15.8018 ABAminus -152.06, 34.97 -157.73, 111.59 -117.56, 21.8 294.76, 97.45 -67.22, -1.53 in-out in 9.2938 Saltbr-out 4.5661 HRD-in -77.37, -44.24 69.01, -4.52 out-in-out SNCoio in-out ActLoopNT-in 2.9141 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -140.21, 38.41 APE9-dihe-in -71.06, 141.9 APE8-dihe-in -59.24, 134.31 APE8-rot-na 17.13 APE67-dihe-in -70.15, -0.4 -63.02, -34.83 APE12-dist-na 13.9123 APE11-dist-na 9.8406 APE10-dist-na 10.3519 APE9-dist-in 5.8386 None PTR1161,PTR1165,PTR1166 PTR1161,PTR1165,PTR1166 XRAY 2.5 0.204 0.257 C 308.0 298.0 7 30 30 0 [[999, 1268]] 1.0 2zm3 TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3D P08069 981 1285 1367.0 575:60001 Type1 Inactive DFGin 6.8241 15.0511 ABAminus -111.39, -39.63 -105.46, 131.68 -127.13, 27.77 299.55, 96.91 -65.49, -19.62 in-out in 9.6873 Saltbr-out 5.2736 HRD-in -74.05, -49.11 76.32, -10.43 out-in-out SNCoio in-out ActLoopNT-in 2.9013 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -119.17, 22.3 APE9-dihe-in -75.96, 143.16 APE8-dihe-in -66.16, 129.67 APE8-rot-na 349.87 APE67-dihe-in -74.71, -7.32 -58.83, -32.73 APE12-dist-na 13.6526 APE11-dist-na 9.7393 APE10-dist-na 9.3004 APE9-dist-in 5.8363 None PTR1161,PTR1165,PTR1166 PTR1161,PTR1165,PTR1166 XRAY 2.5 0.204 0.257 D 308.0 295.0 10 30 30 0 [[999, 1268]] 1.0 2zm3 TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

PDB: 2ZM3 — TYR IGF1R_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 2ZM3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR IGF1R IGF1R_HUMAN 2ZM3A P08069 981 1285 1367.0 575:60001 Type1 Inactive DFGin 6.7889 15.5048 ABAminus -126.6, 3.02 -143.72, 130.04 -129.16, 19.26 296.34, 90.11 -55.9, -25.14 in-out in 9.5268 Saltbr-out 4.8517 HRD-in -72.76, -50.33 77.45, -5.62 out-in-out SNCoio in-out ActLoopNT-in 3.0484 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -118.76, 9.6 APE9-dihe-in -63.6, 138.6 APE8-dihe-in -67.76, 134.68 APE8-rot-na 23.16 APE67-dihe-in -69.69, -0.78 -61.9, -34.84 APE12-dist-na 13.6449 APE11-dist-na 9.8476 APE10-dist-na 9.2254 APE9-dist-in 5.6449 None PTR1161,PTR1165,PTR1166 PTR1161,PTR1165,PTR1166 XRAY 2.5 0.204 0.257 A 308.0 302.0 3 30 30 0 [[999, 1268]] 1.0 2zm3 Homo sapiens TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3B P08069 981 1285 1367.0 575:60001 Type1 Inactive DFGin 6.8979 15.5416 ABAminus -122.17, -30.49 -117.45, 117.57 -113.54, 25.96 293.65, 87.06 -63.47, -21.66 in-out in 9.2709 Saltbr-out 4.7216 HRD-in -70.83, -52.07 75.8, -5.9 out-in-out SNCoio in-out ActLoopNT-in 2.9033 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -116.67, 22.47 APE9-dihe-in -72.91, 143.81 APE8-dihe-in -66.5, 133.93 APE8-rot-na 346.04 APE67-dihe-in -76.24, -7.5 -59.54, -34.53 APE12-dist-na 13.4734 APE11-dist-na 9.742 APE10-dist-na 9.3631 APE9-dist-in 5.8675 None PTR1161,PTR1165,PTR1166 PTR1161,PTR1165,PTR1166 XRAY 2.5 0.204 0.257 B 308.0 298.0 7 30 30 0 [[999, 1268]] 1.0 2zm3 Homo sapiens TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3C P08069 981 1285 1367.0 575:60001 Type1 Inactive DFGin 6.947 15.8018 ABAminus -152.06, 34.97 -157.73, 111.59 -117.56, 21.8 294.76, 97.45 -67.22, -1.53 in-out in 9.2938 Saltbr-out 4.5661 HRD-in -77.37, -44.24 69.01, -4.52 out-in-out SNCoio in-out ActLoopNT-in 2.9141 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -140.21, 38.41 APE9-dihe-in -71.06, 141.9 APE8-dihe-in -59.24, 134.31 APE8-rot-na 17.13 APE67-dihe-in -70.15, -0.4 -63.02, -34.83 APE12-dist-na 13.9123 APE11-dist-na 9.8406 APE10-dist-na 10.3519 APE9-dist-in 5.8386 None PTR1161,PTR1165,PTR1166 PTR1161,PTR1165,PTR1166 XRAY 2.5 0.204 0.257 C 308.0 298.0 7 30 30 0 [[999, 1268]] 1.0 2zm3 Homo sapiens TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3D P08069 981 1285 1367.0 575:60001 Type1 Inactive DFGin 6.8241 15.0511 ABAminus -111.39, -39.63 -105.46, 131.68 -127.13, 27.77 299.55, 96.91 -65.49, -19.62 in-out in 9.6873 Saltbr-out 5.2736 HRD-in -74.05, -49.11 76.32, -10.43 out-in-out SNCoio in-out ActLoopNT-in 2.9013 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -119.17, 22.3 APE9-dihe-in -75.96, 143.16 APE8-dihe-in -66.16, 129.67 APE8-rot-na 349.87 APE67-dihe-in -74.71, -7.32 -58.83, -32.73 APE12-dist-na 13.6526 APE11-dist-na 9.7393 APE10-dist-na 9.3004 APE9-dist-in 5.8363 None PTR1161,PTR1165,PTR1166 PTR1161,PTR1165,PTR1166 XRAY 2.5 0.204 0.257 D 308.0 295.0 10 30 30 0 [[999, 1268]] 1.0 2zm3 Homo sapiens TYR_IGF1R_HUMAN TYR 1.9e-95 325.0 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

PDB: 2ZM3 — TYR IGF1R_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name