PDB: 2Y4I — 2 kinases

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 100.0% 2Y4IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL KSR2 KSR2_HUMAN 2Y4IB Q6VAB6 653 931 950.0 ATP:1932 ATPlike Pseudo DFGin 6.0393 13.3572 BLBplus -163.04, 167.92 56.95, 32.67 -75.07, 155.41 46.1, 92.34 53.05, 51.5 out-none out 15.5798 Saltbr-none 999.0 HRD-in -80.25, -38.53 67.56, -67.09 none-out-out SNCnoo out-out ActLoopNT-out 10.4303 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -56.45, -137.53 APE9-dihe-na -67.8, 7.84 APE8-dihe-out -54.46, -37.41 APE8-rot-na 170.99 APE67-dihe-in -92.05, 13.42 -60.84, -28.22 APE12-dist-out 17.417 APE11-dist-out 14.5757 APE10-dist-out 17.158 APE9-dist-out 12.2619 None None None XRAY 3.46 0.233 0.293 B 319.0 265.0 14 33 23 10 [[665, 930]] 1.0 2y4i TKL_KSR2_HUMAN TKL 1.1e-70 244.1 2.0 267.0 266.0 802 803 804 806 808 692 710 714 783 785 784 786.0 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2

PDB: 2Y4I — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 2Y4IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL KSR2 KSR2_HUMAN 2Y4IB Q6VAB6 653 931 950.0 ATP:1932 ATPlike Pseudo DFGin 6.0393 13.3572 BLBplus -163.04, 167.92 56.95, 32.67 -75.07, 155.41 46.1, 92.34 53.05, 51.5 out-none out 15.5798 Saltbr-none 999.0 HRD-in -80.25, -38.53 67.56, -67.09 none-out-out SNCnoo out-out ActLoopNT-out 10.4303 ActLoopCT-out nonTYR APEdihe_aaoai APEdist_oooo APE10-dihe-na -56.45, -137.53 APE9-dihe-na -67.8, 7.84 APE8-dihe-out -54.46, -37.41 APE8-rot-na 170.99 APE67-dihe-in -92.05, 13.42 -60.84, -28.22 APE12-dist-out 17.417 APE11-dist-out 14.5757 APE10-dist-out 17.158 APE9-dist-out 12.2619 None None None XRAY 3.46 0.233 0.293 B 319.0 265.0 14 33 23 10 [[665, 930]] 1.0 2y4i Homo sapiens TKL_KSR2_HUMAN TKL 1.1e-70 244.1 2.0 267.0 266.0 802 803 804 806 808 692 710 714 783 785 784 786.0 856 835 830 829 828 827 826 825 824 740 Kinase suppressor of Ras 2
STE MAP2K1 MP2K1_RABIT 2Y4IC P29678 37 381 393.0 ATP:1382 ATPlike Inactive DFGin 6.1966 13.7557 BLBplus -151.54, -176.33 53.75, 29.39 -91.07, 130.43 56.39, 97.48 -61.44, 113.3 out-out out 16.1319 Saltbr-out 15.7942 HRD-in -53.6, -47.94 74.29, -22.1 out-out-out SNCooo out-out ActLoopNT-out 9.9 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -108.6, -60.21 APE9-dihe-na 86.78, -165.04 APE8-dihe-out -116.15, -0.77 APE8-rot-out 172.84 APE67-dihe-out -107.13, 167.3 -126.53, 122.47 APE12-dist-out 16.2589 APE11-dist-out 19.1611 APE10-dist-out 21.2782 APE9-dist-out 14.8665 None None None XRAY 3.46 0.233 0.293 C 395.0 313.0 32 26 26 0 [[68, 361]] 1.0 2y4i Oryctolagus cuniculus STE_MAP2K1_RABIT STE 2.5e-97 331.3 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 2Y4I — 2 kinases

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 100.0% 2Y4IC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_RABIT 2Y4IC P29678 37 381 393.0 ATP:1382 ATPlike Inactive DFGin 6.1966 13.7557 BLBplus -151.54, -176.33 53.75, 29.39 -91.07, 130.43 56.39, 97.48 -61.44, 113.3 out-out out 16.1319 Saltbr-out 15.7942 HRD-in -53.6, -47.94 74.29, -22.1 out-out-out SNCooo out-out ActLoopNT-out 9.9 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -108.6, -60.21 APE9-dihe-na 86.78, -165.04 APE8-dihe-out -116.15, -0.77 APE8-rot-out 172.84 APE67-dihe-out -107.13, 167.3 -126.53, 122.47 APE12-dist-out 16.2589 APE11-dist-out 19.1611 APE10-dist-out 21.2782 APE9-dist-out 14.8665 None None None XRAY 3.46 0.233 0.293 C 395.0 313.0 32 26 26 0 [[68, 361]] 1.0 2y4i Oryctolagus cuniculus STE_MAP2K1_RABIT STE 2.5e-97 331.3 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1