Ligand: Y3I

Total number of chains: 7
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 7 100.0% 8FJZC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKCH KPCL_HUMAN 8FP3A P24723 349 679 683.0 Y3I:9000 Type1 Active DFGin 6.22 13.226 BLAminus -127.87, 165.42 68.91, 93.86 -107.42, 16.9 300.66, 99.02 -64.47, -31.74 in-in in 8.835 Saltbr-in 2.953 HRD-in -62.84, -58.95 67.06, -3.18 in-in-in SNCiii in-in ActLoopNT-in 2.931 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -165.98, 170.15 APE9-dihe-na 118.17, 177.41 APE8-dihe-in -88.28, 125.69 APE8-rot-in 312.19 APE67-dihe-in -66.78, -22.74 -44.71, -43.76 APE12-dist-in 8.702 APE11-dist-in 11.681 APE10-dist-in 6.178 APE9-dist-in 3.426 S675E TPO513,TPO656 TPO513,TPO656 XRAY 2.3 0.198 0.256 A 353 331 0 0 0 0 [[355, 614]] 1.0 8fp3 AGC_PRKCH_HUMAN AGC 1.6e-97 331.6 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
STE MAP4K1 M4K1_HUMAN 8FJZA Q92918 3 292 833.0 Y3I:401 Type1 Inactive DFGin 6.51 14.504 BLAminus -137.7, 170.08 62.89, 84.84 -92.48, 16.46 289.48, 97.05 -57.69, -48.7 in-in in 9.024 Saltbr-in 2.853 HRD-in -76.6, -50.02 65.48, 5.07 in-out-out SNCioo out-out ActLoopNT-out 6.147 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -70.77, -28.54 APE9-dihe-na 83.8, -160.52 APE8-dihe-in -69.85, 130.12 APE8-rot-out 203.17 APE67-dihe-in -57.6, -27.08 -102.15, -1.9 APE12-dist-out 19.688 APE11-dist-out 20.668 APE10-dist-out 21.671 APE9-dist-out 28.13 T165E,S171E None None XRAY 1.897 0.216 0.249 A 331 288 2 0 0 0 [[17, 274]] 1.0 8fjz STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZB Q92918 5 292 833.0 Y3I:401 Type1 Inactive DFGin 6.57 14.021 BLAminus -137.02, 169.84 67.81, 83.93 -94.03, 22.71 289.99, 87.03 -64.87, -48.53 in-in in 8.905 Saltbr-in 2.675 HRD-in -75.0, -51.65 69.43, 3.22 in-out-out SNCioo out-out ActLoopNT-out 5.948 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 126.69 APE8-rot-out 63.83 APE67-dihe-in -54.59, -38.97 -101.21, 8.51 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 T165E,S171E None None XRAY 1.897 0.216 0.249 B 331 284 4 0 0 4 [[17, 274]] 1.0 8fjz STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZC Q92918 5 292 833.0 Y3I:401 Type1 Inactive DFGin 6.587 14.237 BLAminus -130.95, 168.73 65.84, 84.49 -90.64, 23.57 288.05, 96.05 -64.63, -46.84 in-in in 8.898 Saltbr-in 2.7 HRD-in -82.44, -52.09 67.55, 1.71 in-out-out SNCioo out-out ActLoopNT-out 6.231 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -63.71, -26.25 APE9-dihe-na 76.16, -172.12 APE8-dihe-in -60.33, 130.84 APE8-rot-out 195.91 APE67-dihe-in -63.98, -25.54 -102.76, 2.25 APE12-dist-out 19.401 APE11-dist-out 20.592 APE10-dist-out 21.738 APE9-dist-out 28.12 T165E,S171E None None XRAY 1.897 0.216 0.249 C 331 288 0 0 0 0 [[17, 274]] 1.0 8fjz STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZD Q92918 5 292 833.0 Y3I:401 Type1 Inactive DFGin 6.717 14.041 BLAminus -137.08, 171.73 59.36, 82.37 -86.27, 18.66 292.08, 95.93 -58.09, -54.94 in-in in 8.988 Saltbr-in 2.732 HRD-in -69.09, -53.22 71.65, -0.73 in-out-out SNCioo out-out ActLoopNT-out 6.095 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -148.42 APE8-dihe-in -68.43, 138.08 APE8-rot-out 39.71 APE67-dihe-in -52.93, -33.25 -97.78, -5.14 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 28.327 T165E,S171E None None XRAY 1.897 0.216 0.249 D 331 279 9 0 0 5 [[17, 274]] 1.0 8fjz STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZE Q92918 6 292 833.0 Y3I:401 Type1 Inactive DFGin 6.774 14.099 BLAminus -136.75, 169.37 68.25, 86.68 -95.74, 24.36 294.3, 85.62 -65.14, -47.45 in-in in 8.919 Saltbr-in 2.724 HRD-in -74.26, -49.77 67.78, 3.39 in-out-out SNCioo out-out ActLoopNT-out 6.066 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -56.26, -48.49 APE9-dihe-na 80.16, 179.63 APE8-dihe-in -54.87, 130.2 APE8-rot-in 306.01 APE67-dihe-in -57.58, -32.37 -99.48, -10.41 APE12-dist-out 19.306 APE11-dist-out 20.62 APE10-dist-out 22.177 APE9-dist-out 28.139 T165E,S171E None None XRAY 1.897 0.216 0.249 E 331 283 4 0 0 0 [[17, 274]] 1.0 8fjz STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZF Q92918 9 292 833.0 Y3I:401 Type1 Inactive DFGin 6.754 14.514 BLAminus -131.7, 172.77 61.74, 84.47 -90.86, 22.68 286.38, 91.5 -60.13, -49.97 in-in in 9.121 Saltbr-in 2.741 HRD-in -74.14, -51.77 66.66, 4.96 in-out-out SNCioo out-out ActLoopNT-out 5.986 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -63.64, -30.73 APE9-dihe-na 73.64, -165.36 APE8-dihe-in -58.14, 130.21 APE8-rot-out 197.86 APE67-dihe-in -59.67, -30.33 -96.67, -2.31 APE12-dist-out 19.267 APE11-dist-out 20.726 APE10-dist-out 21.359 APE9-dist-out 27.978 T165E,S171E None None XRAY 1.897 0.216 0.249 F 331 276 8 0 0 0 [[17, 274]] 1.0 8fjz STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1

Ligand: Y3I

Total number of chains: 7
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 7 100.0% 8FJZC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKCH KPCL_HUMAN 8FP3A P24723 349 679 683.0 Y3I:9000 Type1 Active DFGin 6.22 13.226 BLAminus -127.87, 165.42 68.91, 93.86 -107.42, 16.9 300.66, 99.02 -64.47, -31.74 in-in in 8.835 Saltbr-in 2.953 HRD-in -62.84, -58.95 67.06, -3.18 in-in-in SNCiii in-in ActLoopNT-in 2.931 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -165.98, 170.15 APE9-dihe-na 118.17, 177.41 APE8-dihe-in -88.28, 125.69 APE8-rot-in 312.19 APE67-dihe-in -66.78, -22.74 -44.71, -43.76 APE12-dist-in 8.702 APE11-dist-in 11.681 APE10-dist-in 6.178 APE9-dist-in 3.426 S675E TPO513,TPO656 TPO513,TPO656 XRAY 2.3 0.198 0.256 A 353 331 0 0 0 0 [[355, 614]] 1.0 8fp3 Homo sapiens AGC_PRKCH_HUMAN AGC 1.6e-97 331.6 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
STE MAP4K1 M4K1_HUMAN 8FJZA Q92918 3 292 833.0 Y3I:401 Type1 Inactive DFGin 6.51 14.504 BLAminus -137.7, 170.08 62.89, 84.84 -92.48, 16.46 289.48, 97.05 -57.69, -48.7 in-in in 9.024 Saltbr-in 2.853 HRD-in -76.6, -50.02 65.48, 5.07 in-out-out SNCioo out-out ActLoopNT-out 6.147 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -70.77, -28.54 APE9-dihe-na 83.8, -160.52 APE8-dihe-in -69.85, 130.12 APE8-rot-out 203.17 APE67-dihe-in -57.6, -27.08 -102.15, -1.9 APE12-dist-out 19.688 APE11-dist-out 20.668 APE10-dist-out 21.671 APE9-dist-out 28.13 T165E,S171E None None XRAY 1.897 0.216 0.249 A 331 288 2 0 0 0 [[17, 274]] 1.0 8fjz Homo sapiens STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZB Q92918 5 292 833.0 Y3I:401 Type1 Inactive DFGin 6.57 14.021 BLAminus -137.02, 169.84 67.81, 83.93 -94.03, 22.71 289.99, 87.03 -64.87, -48.53 in-in in 8.905 Saltbr-in 2.675 HRD-in -75.0, -51.65 69.43, 3.22 in-out-out SNCioo out-out ActLoopNT-out 5.948 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 126.69 APE8-rot-out 63.83 APE67-dihe-in -54.59, -38.97 -101.21, 8.51 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 T165E,S171E None None XRAY 1.897 0.216 0.249 B 331 284 4 0 0 4 [[17, 274]] 1.0 8fjz Homo sapiens STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZC Q92918 5 292 833.0 Y3I:401 Type1 Inactive DFGin 6.587 14.237 BLAminus -130.95, 168.73 65.84, 84.49 -90.64, 23.57 288.05, 96.05 -64.63, -46.84 in-in in 8.898 Saltbr-in 2.7 HRD-in -82.44, -52.09 67.55, 1.71 in-out-out SNCioo out-out ActLoopNT-out 6.231 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -63.71, -26.25 APE9-dihe-na 76.16, -172.12 APE8-dihe-in -60.33, 130.84 APE8-rot-out 195.91 APE67-dihe-in -63.98, -25.54 -102.76, 2.25 APE12-dist-out 19.401 APE11-dist-out 20.592 APE10-dist-out 21.738 APE9-dist-out 28.12 T165E,S171E None None XRAY 1.897 0.216 0.249 C 331 288 0 0 0 0 [[17, 274]] 1.0 8fjz Homo sapiens STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZD Q92918 5 292 833.0 Y3I:401 Type1 Inactive DFGin 6.717 14.041 BLAminus -137.08, 171.73 59.36, 82.37 -86.27, 18.66 292.08, 95.93 -58.09, -54.94 in-in in 8.988 Saltbr-in 2.732 HRD-in -69.09, -53.22 71.65, -0.73 in-out-out SNCioo out-out ActLoopNT-out 6.095 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -148.42 APE8-dihe-in -68.43, 138.08 APE8-rot-out 39.71 APE67-dihe-in -52.93, -33.25 -97.78, -5.14 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 28.327 T165E,S171E None None XRAY 1.897 0.216 0.249 D 331 279 9 0 0 5 [[17, 274]] 1.0 8fjz Homo sapiens STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZE Q92918 6 292 833.0 Y3I:401 Type1 Inactive DFGin 6.774 14.099 BLAminus -136.75, 169.37 68.25, 86.68 -95.74, 24.36 294.3, 85.62 -65.14, -47.45 in-in in 8.919 Saltbr-in 2.724 HRD-in -74.26, -49.77 67.78, 3.39 in-out-out SNCioo out-out ActLoopNT-out 6.066 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -56.26, -48.49 APE9-dihe-na 80.16, 179.63 APE8-dihe-in -54.87, 130.2 APE8-rot-in 306.01 APE67-dihe-in -57.58, -32.37 -99.48, -10.41 APE12-dist-out 19.306 APE11-dist-out 20.62 APE10-dist-out 22.177 APE9-dist-out 28.139 T165E,S171E None None XRAY 1.897 0.216 0.249 E 331 283 4 0 0 0 [[17, 274]] 1.0 8fjz Homo sapiens STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8FJZF Q92918 9 292 833.0 Y3I:401 Type1 Inactive DFGin 6.754 14.514 BLAminus -131.7, 172.77 61.74, 84.47 -90.86, 22.68 286.38, 91.5 -60.13, -49.97 in-in in 9.121 Saltbr-in 2.741 HRD-in -74.14, -51.77 66.66, 4.96 in-out-out SNCioo out-out ActLoopNT-out 5.986 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -63.64, -30.73 APE9-dihe-na 73.64, -165.36 APE8-dihe-in -58.14, 130.21 APE8-rot-out 197.86 APE67-dihe-in -59.67, -30.33 -96.67, -2.31 APE12-dist-out 19.267 APE11-dist-out 20.726 APE10-dist-out 21.359 APE9-dist-out 27.978 T165E,S171E None None XRAY 1.897 0.216 0.249 F 331 276 8 0 0 0 [[17, 274]] 1.0 8fjz Homo sapiens STE_MAP4K1_HUMAN STE 6.2e-92 313.5 1 256 256 154 155 156 158 160 46 62 66 134 136 135 137 197 182 177 176 175 174 173 172 171 92 Mitogen-activated protein kinase kinase kinase kinase 1

Ligand: Y3I

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name