Ligand: WIQ

Total number of chains: 5
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 3 60.0% 8UDVA
DFGin BLAminus 1 20.0% 8UDUB
DFGin BLBplus 1 20.0% 8UDUA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR3 FGFR3_HUMAN 8UDUB P22607 459 755 806.0 WIQ:61002 Type1.5_Front Active DFGin 6.421 14.415 BLAminus -138.69, 176.26 64.2, 86.01 -100.28, 24.84 287.71, 79.66 -57.6, -41.09 in-in in 8.185 Saltbr-in 2.946 HRD-in -71.69, -47.92 71.62, 0.22 in-in-in SNCiii in-in ActLoopNT-in 2.947 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.88, 155.75 APE9-dihe-in -122.51, 89.95 APE8-dihe-in -81.37, 70.05 APE8-rot-na 30.61 APE67-dihe-in -66.22, -12.9 -45.0, -50.18 APE12-dist-na 999.0 APE11-dist-na 7.661 APE10-dist-na 8.489 APE9-dist-in 7.717 P572S,P573G None None XRAY 1.737 0.231 0.256 B 297 276 9 0 0 1 [[472, 750]] 1.0 8udu TYR_FGFR3_HUMAN TYR 8.4e-105 355.7 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVA P22607 458 755 806.0 WIQ:1003 Type1.5_Back Inactive DFGin 6.001 13.476 BLAplus -124.26, 161.29 66.5, 36.68 -91.33, -43.75 46.96, 90.73 -84.73, 13.25 in-in in 7.661 Saltbr-in 2.94 HRD-in -66.26, -46.33 75.0, -11.55 in-out-out SNCioo out-out ActLoopNT-out 8.16 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -144.63, 151.27 APE9-dihe-in -107.88, 92.32 APE8-dihe-out -54.6, -21.22 APE8-rot-na 338.66 APE67-dihe-in -68.84, -8.83 -57.22, -29.15 APE12-dist-na 15.956 APE11-dist-na 19.998 APE10-dist-na 17.285 APE9-dist-out 11.612 V555M None None XRAY 2.348 0.237 0.261 A 297 279 7 0 0 7 [[472, 750]] 1.0 8udv TYR_FGFR3_HUMAN TYR 4.5e-105 356.6 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVB P22607 455 755 806.0 WIQ:803 Type1.5_Back Inactive DFGin 5.481 13.254 BLAplus -124.6, 164.38 63.05, 27.71 -82.13, -38.21 55.85, 89.15 -91.32, 13.57 in-in in 7.68 Saltbr-in 2.904 HRD-in -63.59, -46.44 79.4, -13.95 in-out-out SNCioo out-out ActLoopNT-out 8.907 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -136.87, 152.88 APE9-dihe-in -110.79, 96.93 APE8-dihe-out -58.89, -20.81 APE8-rot-na 338.74 APE67-dihe-in -70.46, -8.74 -52.69, -32.19 APE12-dist-na 15.479 APE11-dist-na 19.386 APE10-dist-na 16.703 APE9-dist-out 11.424 V555M None None XRAY 2.348 0.237 0.261 B 297 281 8 0 0 8 [[472, 750]] 1.0 8udv TYR_FGFR3_HUMAN TYR 4.5e-105 356.6 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVC P22607 458 755 806.0 WIQ:1004 Type1.5_Back Inactive DFGin 6.071 13.431 BLAplus -124.65, 164.21 70.39, 38.16 -109.8, -21.91 57.41, 87.59 -78.9, -34.05 in-in in 7.655 Saltbr-in 2.888 HRD-in -64.72, -49.48 77.07, -10.54 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 91.25 APE8-dihe-out -54.32, -20.59 APE8-rot-na 338.75 APE67-dihe-in -71.87, -8.91 -59.36, -26.12 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.626 V555M None None XRAY 2.348 0.237 0.261 C 297 269 17 0 0 16 [[472, 750]] 1.0 8udv TYR_FGFR3_HUMAN TYR 4.5e-105 356.6 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDUA P22607 460 756 806.0 WIQ:61002 Type1.5_Back Inactive DFGin 5.761 13.529 BLBplus -121.3, 171.32 71.72, 21.7 -99.77, 166.76 66.11, 93.34 95.58, -59.45 in-in in 7.917 Saltbr-in 2.734 HRD-in -77.2, -48.45 77.61, -12.83 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -71.65, 162.44 APE9-dihe-in -54.1, 129.25 APE8-dihe-in -83.64, 61.19 APE8-rot-na 34.62 APE67-dihe-in -73.43, -8.03 -52.16, -35.97 APE12-dist-na 999.0 APE11-dist-na 14.232 APE10-dist-na 17.747 APE9-dist-out 8.253 P572S,P573G None None XRAY 1.737 0.231 0.256 A 297 277 8 0 0 8 [[472, 750]] 1.0 8udu TYR_FGFR3_HUMAN TYR 8.4e-105 355.7 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

Ligand: WIQ

Total number of chains: 5
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 3 60.0% 8UDVA
DFGin BLAminus 1 20.0% 8UDUB
DFGin BLBplus 1 20.0% 8UDUA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR3 FGFR3_HUMAN 8UDUB P22607 459 755 806.0 WIQ:61002 Type1.5_Front Active DFGin 6.421 14.415 BLAminus -138.69, 176.26 64.2, 86.01 -100.28, 24.84 287.71, 79.66 -57.6, -41.09 in-in in 8.185 Saltbr-in 2.946 HRD-in -71.69, -47.92 71.62, 0.22 in-in-in SNCiii in-in ActLoopNT-in 2.947 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.88, 155.75 APE9-dihe-in -122.51, 89.95 APE8-dihe-in -81.37, 70.05 APE8-rot-na 30.61 APE67-dihe-in -66.22, -12.9 -45.0, -50.18 APE12-dist-na 999.0 APE11-dist-na 7.661 APE10-dist-na 8.489 APE9-dist-in 7.717 P572S,P573G None None XRAY 1.737 0.231 0.256 B 297 276 9 0 0 1 [[472, 750]] 1.0 8udu Homo sapiens TYR_FGFR3_HUMAN TYR 8.4e-105 355.7 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVA P22607 458 755 806.0 WIQ:1003 Type1.5_Back Inactive DFGin 6.001 13.476 BLAplus -124.26, 161.29 66.5, 36.68 -91.33, -43.75 46.96, 90.73 -84.73, 13.25 in-in in 7.661 Saltbr-in 2.94 HRD-in -66.26, -46.33 75.0, -11.55 in-out-out SNCioo out-out ActLoopNT-out 8.16 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -144.63, 151.27 APE9-dihe-in -107.88, 92.32 APE8-dihe-out -54.6, -21.22 APE8-rot-na 338.66 APE67-dihe-in -68.84, -8.83 -57.22, -29.15 APE12-dist-na 15.956 APE11-dist-na 19.998 APE10-dist-na 17.285 APE9-dist-out 11.612 V555M None None XRAY 2.348 0.237 0.261 A 297 279 7 0 0 7 [[472, 750]] 1.0 8udv Homo sapiens TYR_FGFR3_HUMAN TYR 4.5e-105 356.6 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVB P22607 455 755 806.0 WIQ:803 Type1.5_Back Inactive DFGin 5.481 13.254 BLAplus -124.6, 164.38 63.05, 27.71 -82.13, -38.21 55.85, 89.15 -91.32, 13.57 in-in in 7.68 Saltbr-in 2.904 HRD-in -63.59, -46.44 79.4, -13.95 in-out-out SNCioo out-out ActLoopNT-out 8.907 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -136.87, 152.88 APE9-dihe-in -110.79, 96.93 APE8-dihe-out -58.89, -20.81 APE8-rot-na 338.74 APE67-dihe-in -70.46, -8.74 -52.69, -32.19 APE12-dist-na 15.479 APE11-dist-na 19.386 APE10-dist-na 16.703 APE9-dist-out 11.424 V555M None None XRAY 2.348 0.237 0.261 B 297 281 8 0 0 8 [[472, 750]] 1.0 8udv Homo sapiens TYR_FGFR3_HUMAN TYR 4.5e-105 356.6 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVC P22607 458 755 806.0 WIQ:1004 Type1.5_Back Inactive DFGin 6.071 13.431 BLAplus -124.65, 164.21 70.39, 38.16 -109.8, -21.91 57.41, 87.59 -78.9, -34.05 in-in in 7.655 Saltbr-in 2.888 HRD-in -64.72, -49.48 77.07, -10.54 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 91.25 APE8-dihe-out -54.32, -20.59 APE8-rot-na 338.75 APE67-dihe-in -71.87, -8.91 -59.36, -26.12 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.626 V555M None None XRAY 2.348 0.237 0.261 C 297 269 17 0 0 16 [[472, 750]] 1.0 8udv Homo sapiens TYR_FGFR3_HUMAN TYR 4.5e-105 356.6 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDUA P22607 460 756 806.0 WIQ:61002 Type1.5_Back Inactive DFGin 5.761 13.529 BLBplus -121.3, 171.32 71.72, 21.7 -99.77, 166.76 66.11, 93.34 95.58, -59.45 in-in in 7.917 Saltbr-in 2.734 HRD-in -77.2, -48.45 77.61, -12.83 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -71.65, 162.44 APE9-dihe-in -54.1, 129.25 APE8-dihe-in -83.64, 61.19 APE8-rot-na 34.62 APE67-dihe-in -73.43, -8.03 -52.16, -35.97 APE12-dist-na 999.0 APE11-dist-na 14.232 APE10-dist-na 17.747 APE9-dist-out 8.253 P572S,P573G None None XRAY 1.737 0.231 0.256 A 297 277 8 0 0 8 [[472, 750]] 1.0 8udu Homo sapiens TYR_FGFR3_HUMAN TYR 8.4e-105 355.7 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

Ligand: WIQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name