Ligand: WEJ (Bezuclastinib)

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7KHKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR KIT KIT_HUMAN 7KHKA 2.34 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai WEJ Type1 566 - 931 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHKB 2.34 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai WEJ Type1.5_Back 567 - 929 0 None None Mast/stem cell growth factor receptor Kit

Ligand: WEJ (Bezuclastinib)

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7KHKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR KIT KIT_HUMAN 7KHKA 2.34 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai WEJ Type1 566 - 931 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 7KHKB 2.34 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai WEJ Type1.5_Back 567 - 929 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens

Ligand: WEJ (Bezuclastinib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism