Ligand: W4A

Total number of chains: 5
Active chains: 5
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 5MYVA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC SRPK1 SRPK1_HUMAN 5MXXA 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 56 - 655 0 None None SRSF protein kinase 1
CMGC SRPK2 SRPK2_HUMAN 5MYVA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2
CMGC SRPK2 SRPK2_HUMAN 5MYVB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2
CMGC SRPK2 SRPK2_HUMAN 5MYVC 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2
CMGC SRPK2 SRPK2_HUMAN 5MYVD 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2

Ligand: W4A

Total number of chains: 5
Active chains: 5
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 5MYVA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC SRPK1 SRPK1_HUMAN 5MXXA 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 56 - 655 0 None None SRSF protein kinase 1 Homo sapiens
CMGC SRPK2 SRPK2_HUMAN 5MYVA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2 Homo sapiens
CMGC SRPK2 SRPK2_HUMAN 5MYVB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2 Homo sapiens
CMGC SRPK2 SRPK2_HUMAN 5MYVC 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2 Homo sapiens
CMGC SRPK2 SRPK2_HUMAN 5MYVD 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2 Homo sapiens

Ligand: W4A

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
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Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism