Ligand: VVW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8KH8A
DFGin BLBplus 1 33.3% 8KH9A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR4 FGFR4_HUMAN 8KH8A P22455 453 751 802.0 VVW:802 Type1 Inactive DFGin 5.473 13.134 BLAplus -118.53, 158.78 61.66, 36.82 -83.32, -20.9 47.14, 88.2 -101.16, 42.7 in-in in 7.514 Saltbr-in 2.669 HRD-in -75.42, -56.09 83.49, -11.36 in-out-out SNCioo out-out ActLoopNT-out 8.748 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.21, 138.97 APE9-dihe-in -107.92, 92.76 APE8-dihe-out -57.64, -22.35 APE8-rot-na 332.41 APE67-dihe-in -70.15, -6.75 -57.07, -25.4 APE12-dist-na 19.944 APE11-dist-na 21.486 APE10-dist-na 17.34 APE9-dist-out 11.91 C477A,V550L,R664E None None XRAY 1.49 0.169 0.197 A 309 299 0 0 0 0 [[467, 745]] 1.0 8kh8 TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1 261 261 629 630 631 633 635 503 520 524 609 611 610 612 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH7A P22455 454 751 802.0 VVW:802 Type1 Inactive DFGin 5.276 12.722 BLAplus -115.76, 162.05 57.7, 35.04 -83.79, -12.86 51.09, 87.09 -105.89, 24.32 in-in in 7.417 Saltbr-in 2.782 HRD-in -69.92, -54.01 83.03, -10.74 in-out-out SNCioo out-out ActLoopNT-out 8.514 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -75.04, 139.88 APE9-dihe-in -109.97, 90.79 APE8-dihe-out -58.47, -20.09 APE8-rot-na 333.49 APE67-dihe-in -69.7, -7.45 -60.7, -23.51 APE12-dist-na 19.798 APE11-dist-na 21.421 APE10-dist-na 17.266 APE9-dist-out 11.991 R664E None None XRAY 1.52 0.166 0.195 A 311 290 8 0 0 0 [[467, 745]] 1.0 8kh7 TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1 261 261 629 630 631 633 635 503 520 524 609 611 610 612 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH9A P22455 454 752 802.0 VVW:903 Type1 Inactive DFGin 5.628 13.229 BLBplus -116.73, 162.01 54.49, 42.82 -90.48, 158.22 47.04, 88.15 53.89, 22.89 in-in in 7.539 Saltbr-in 2.692 HRD-in -76.16, -55.94 82.55, -10.33 in-out-out SNCioo out-out ActLoopNT-out 8.722 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.55, 140.78 APE9-dihe-in -111.22, 92.1 APE8-dihe-out -57.69, -22.37 APE8-rot-na 333.28 APE67-dihe-in -71.01, -5.51 -56.46, -26.43 APE12-dist-na 20.313 APE11-dist-na 21.834 APE10-dist-na 17.588 APE9-dist-out 11.963 C477A,V550M,R664E None None XRAY 1.42 0.171 0.193 A 300 299 0 0 0 0 [[467, 745]] 1.0 8kh9 TYR_FGFR4_HUMAN TYR 6.3e-101 343.0 1 261 261 629 630 631 633 635 503 520 524 609 611 610 612 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: VVW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8KH8A
DFGin BLBplus 1 33.3% 8KH9A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR4 FGFR4_HUMAN 8KH8A P22455 453 751 802.0 VVW:802 Type1 Inactive DFGin 5.473 13.134 BLAplus -118.53, 158.78 61.66, 36.82 -83.32, -20.9 47.14, 88.2 -101.16, 42.7 in-in in 7.514 Saltbr-in 2.669 HRD-in -75.42, -56.09 83.49, -11.36 in-out-out SNCioo out-out ActLoopNT-out 8.748 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.21, 138.97 APE9-dihe-in -107.92, 92.76 APE8-dihe-out -57.64, -22.35 APE8-rot-na 332.41 APE67-dihe-in -70.15, -6.75 -57.07, -25.4 APE12-dist-na 19.944 APE11-dist-na 21.486 APE10-dist-na 17.34 APE9-dist-out 11.91 C477A,V550L,R664E None None XRAY 1.49 0.169 0.197 A 309 299 0 0 0 0 [[467, 745]] 1.0 8kh8 Homo sapiens TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1 261 261 629 630 631 633 635 503 520 524 609 611 610 612 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH7A P22455 454 751 802.0 VVW:802 Type1 Inactive DFGin 5.276 12.722 BLAplus -115.76, 162.05 57.7, 35.04 -83.79, -12.86 51.09, 87.09 -105.89, 24.32 in-in in 7.417 Saltbr-in 2.782 HRD-in -69.92, -54.01 83.03, -10.74 in-out-out SNCioo out-out ActLoopNT-out 8.514 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -75.04, 139.88 APE9-dihe-in -109.97, 90.79 APE8-dihe-out -58.47, -20.09 APE8-rot-na 333.49 APE67-dihe-in -69.7, -7.45 -60.7, -23.51 APE12-dist-na 19.798 APE11-dist-na 21.421 APE10-dist-na 17.266 APE9-dist-out 11.991 R664E None None XRAY 1.52 0.166 0.195 A 311 290 8 0 0 0 [[467, 745]] 1.0 8kh7 Homo sapiens TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1 261 261 629 630 631 633 635 503 520 524 609 611 610 612 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH9A P22455 454 752 802.0 VVW:903 Type1 Inactive DFGin 5.628 13.229 BLBplus -116.73, 162.01 54.49, 42.82 -90.48, 158.22 47.04, 88.15 53.89, 22.89 in-in in 7.539 Saltbr-in 2.692 HRD-in -76.16, -55.94 82.55, -10.33 in-out-out SNCioo out-out ActLoopNT-out 8.722 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.55, 140.78 APE9-dihe-in -111.22, 92.1 APE8-dihe-out -57.69, -22.37 APE8-rot-na 333.28 APE67-dihe-in -71.01, -5.51 -56.46, -26.43 APE12-dist-na 20.313 APE11-dist-na 21.834 APE10-dist-na 17.588 APE9-dist-out 11.963 C477A,V550M,R664E None None XRAY 1.42 0.171 0.193 A 300 299 0 0 0 0 [[467, 745]] 1.0 8kh9 Homo sapiens TYR_FGFR4_HUMAN TYR 6.3e-101 343.0 1 261 261 629 630 631 633 635 503 520 524 609 611 610 612 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: VVW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name