Ligand: VVW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8KH8A
DFGin BLBplus 1 33.3% 8KH9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR4 FGFR4_HUMAN 8KH8A P22455 453 751 802.0 VVW:802 Type1 Inactive DFGin 5.4727 13.1344 BLAplus -118.53, 158.78 61.66, 36.82 -83.32, -20.9 47.14, 88.2 -101.16, 42.7 in-in in 7.5141 Saltbr-in 2.6689 HRD-in -75.42, -56.09 83.49, -11.36 in-out-out SNCioo out-out ActLoopNT-out 8.7477 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.21, 138.97 APE9-dihe-in -107.92, 92.76 APE8-dihe-out -57.64, -22.35 APE8-rot-na 332.41 APE67-dihe-in -70.15, -6.75 -57.07, -25.4 APE12-dist-na 19.9437 APE11-dist-na 21.4858 APE10-dist-na 17.3401 APE9-dist-out 11.9102 C477A,V550L,R664E None None XRAY 1.49 0.169 0.197 A 309.0 299.0 0 30 30 0 [[467, 745]] 1.0 8kh8 TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH7A P22455 454 751 802.0 VVW:802 Type1 Inactive DFGin 5.2756 12.7215 BLAplus -115.76, 162.05 57.7, 35.04 -83.79, -12.86 51.09, 87.09 -105.89, 24.32 in-in in 7.4168 Saltbr-in 2.7818 HRD-in -69.92, -54.01 83.03, -10.74 in-out-out SNCioo out-out ActLoopNT-out 8.5138 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -75.04, 139.88 APE9-dihe-in -109.97, 90.79 APE8-dihe-out -58.47, -20.09 APE8-rot-na 333.49 APE67-dihe-in -69.7, -7.45 -60.7, -23.51 APE12-dist-na 19.7984 APE11-dist-na 21.4206 APE10-dist-na 17.2658 APE9-dist-out 11.9913 R664E None None XRAY 1.52 0.166 0.195 A 311.0 290.0 8 30 30 0 [[467, 745]] 1.0 8kh7 TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH9A P22455 454 752 802.0 VVW:903 Type1 Inactive DFGin 5.6284 13.2287 BLBplus -116.73, 162.01 54.49, 42.82 -90.48, 158.22 47.04, 88.15 53.89, 22.89 in-in in 7.5394 Saltbr-in 2.6915 HRD-in -76.16, -55.94 82.55, -10.33 in-out-out SNCioo out-out ActLoopNT-out 8.7222 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.55, 140.78 APE9-dihe-in -111.22, 92.1 APE8-dihe-out -57.69, -22.37 APE8-rot-na 333.28 APE67-dihe-in -71.01, -5.51 -56.46, -26.43 APE12-dist-na 20.3132 APE11-dist-na 21.8343 APE10-dist-na 17.5883 APE9-dist-out 11.963 C477A,V550M,R664E None None XRAY 1.42 0.171 0.193 A 300.0 299.0 0 30 30 0 [[467, 745]] 1.0 8kh9 TYR_FGFR4_HUMAN TYR 6.3e-101 343.0 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: VVW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8KH8A
DFGin BLBplus 1 33.3% 8KH9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR4 FGFR4_HUMAN 8KH8A P22455 453 751 802.0 VVW:802 Type1 Inactive DFGin 5.4727 13.1344 BLAplus -118.53, 158.78 61.66, 36.82 -83.32, -20.9 47.14, 88.2 -101.16, 42.7 in-in in 7.5141 Saltbr-in 2.6689 HRD-in -75.42, -56.09 83.49, -11.36 in-out-out SNCioo out-out ActLoopNT-out 8.7477 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.21, 138.97 APE9-dihe-in -107.92, 92.76 APE8-dihe-out -57.64, -22.35 APE8-rot-na 332.41 APE67-dihe-in -70.15, -6.75 -57.07, -25.4 APE12-dist-na 19.9437 APE11-dist-na 21.4858 APE10-dist-na 17.3401 APE9-dist-out 11.9102 C477A,V550L,R664E None None XRAY 1.49 0.169 0.197 A 309.0 299.0 0 30 30 0 [[467, 745]] 1.0 8kh8 Homo sapiens TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH7A P22455 454 751 802.0 VVW:802 Type1 Inactive DFGin 5.2756 12.7215 BLAplus -115.76, 162.05 57.7, 35.04 -83.79, -12.86 51.09, 87.09 -105.89, 24.32 in-in in 7.4168 Saltbr-in 2.7818 HRD-in -69.92, -54.01 83.03, -10.74 in-out-out SNCioo out-out ActLoopNT-out 8.5138 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -75.04, 139.88 APE9-dihe-in -109.97, 90.79 APE8-dihe-out -58.47, -20.09 APE8-rot-na 333.49 APE67-dihe-in -69.7, -7.45 -60.7, -23.51 APE12-dist-na 19.7984 APE11-dist-na 21.4206 APE10-dist-na 17.2658 APE9-dist-out 11.9913 R664E None None XRAY 1.52 0.166 0.195 A 311.0 290.0 8 30 30 0 [[467, 745]] 1.0 8kh7 Homo sapiens TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH9A P22455 454 752 802.0 VVW:903 Type1 Inactive DFGin 5.6284 13.2287 BLBplus -116.73, 162.01 54.49, 42.82 -90.48, 158.22 47.04, 88.15 53.89, 22.89 in-in in 7.5394 Saltbr-in 2.6915 HRD-in -76.16, -55.94 82.55, -10.33 in-out-out SNCioo out-out ActLoopNT-out 8.7222 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.55, 140.78 APE9-dihe-in -111.22, 92.1 APE8-dihe-out -57.69, -22.37 APE8-rot-na 333.28 APE67-dihe-in -71.01, -5.51 -56.46, -26.43 APE12-dist-na 20.3132 APE11-dist-na 21.8343 APE10-dist-na 17.5883 APE9-dist-out 11.963 C477A,V550M,R664E None None XRAY 1.42 0.171 0.193 A 300.0 299.0 0 30 30 0 [[467, 745]] 1.0 8kh9 Homo sapiens TYR_FGFR4_HUMAN TYR 6.3e-101 343.0 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: VVW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name