Ligand: VQP

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 4 100.0% 7K0VD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 7K0VA P15056 449 722 766.0 VQP:801 Type2 Inactive DFGout 12.195 11.918 BBAminus -162.68, -156.07 -117.9, 96.89 -109.54, 16.15 299.04, 103.45 -77.91, 116.59 in-in in 8.676 Saltbr-in 3.148 HRD-in -72.28, -41.59 81.4, -9.83 in-out-out SNCioo out-out ActLoopNT-out 23.093 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -92.4, 141.9 APE9-dihe-na -84.31, -172.93 APE8-dihe-in -81.24, 56.12 APE8-rot-in 309.48 APE67-dihe-in -74.89, -22.92 -59.56, -24.75 APE12-dist-in 9.752 APE11-dist-out 15.297 APE10-dist-out 14.399 APE9-dist-out 8.984 None None None XRAY 1.93 0.187 0.23 A 288 262 12 0 0 9 [[457, 716]] 1.0 7k0v TKL_BRAF_HUMAN TKL 5.8e-84 287.7 4 267 264 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VB P15056 449 722 766.0 VQP:801 Type2 Inactive DFGout 12.34 11.701 BBAminus -167.19, -159.19 -104.12, 109.97 -117.14, 1.82 293.72, 96.78 -102.83, -58.49 in-in in 8.352 Saltbr-in 2.756 HRD-in -71.48, -47.17 73.94, -6.06 in-out-out SNCioo out-out ActLoopNT-out 14.087 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -97.2, 2.25 APE9-dihe-na 176.29, 177.5 APE8-dihe-out 64.18, 15.92 APE8-rot-in 287.72 APE67-dihe-in -68.76, -19.22 -66.09, -26.1 APE12-dist-out 14.721 APE11-dist-out 16.447 APE10-dist-out 12.441 APE9-dist-out 10.103 None None None XRAY 1.93 0.187 0.23 B 288 264 10 0 0 7 [[457, 716]] 1.0 7k0v TKL_BRAF_HUMAN TKL 5.8e-84 287.7 4 267 264 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VC P15056 448 722 766.0 VQP:801 Type2 Inactive DFGout 12.415 11.312 BBAminus -149.63, -160.06 -140.65, 98.9 -96.4, 9.54 307.52, 103.4 -76.49, 147.45 in-in in 8.558 Saltbr-in 2.727 HRD-in -65.37, -52.41 83.32, -6.12 in-out-out SNCioo out-out ActLoopNT-out 18.181 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -119.69 APE8-dihe-out -98.34, 2.05 APE8-rot-in 283.36 APE67-dihe-in -63.48, -24.0 -64.49, -30.31 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.091 None None None XRAY 1.93 0.187 0.23 C 288 267 8 0 0 8 [[457, 716]] 1.0 7k0v TKL_BRAF_HUMAN TKL 5.8e-84 287.7 4 267 264 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VD P15056 449 722 766.0 VQP:801 Type2 Inactive DFGout 12.377 11.418 BBAminus -149.15, -161.3 -137.52, 97.73 -97.03, 6.48 305.14, 104.21 -74.28, 146.89 in-in in 8.685 Saltbr-in 2.725 HRD-in -66.71, -47.33 78.8, -19.85 in-out-out SNCioo out-out ActLoopNT-out 18.689 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -56.48, -29.5 APE9-dihe-na -75.21, -5.78 APE8-dihe-out -116.03, -0.39 APE8-rot-in 294.97 APE67-dihe-in -63.2, -20.28 -68.0, -40.36 APE12-dist-in 10.95 APE11-dist-in 12.547 APE10-dist-out 13.523 APE9-dist-out 10.751 None None None XRAY 1.93 0.187 0.23 D 288 271 3 0 0 3 [[457, 716]] 1.0 7k0v TKL_BRAF_HUMAN TKL 5.8e-84 287.7 4 267 264 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

Ligand: VQP

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 4 100.0% 7K0VD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 7K0VA P15056 449 722 766.0 VQP:801 Type2 Inactive DFGout 12.195 11.918 BBAminus -162.68, -156.07 -117.9, 96.89 -109.54, 16.15 299.04, 103.45 -77.91, 116.59 in-in in 8.676 Saltbr-in 3.148 HRD-in -72.28, -41.59 81.4, -9.83 in-out-out SNCioo out-out ActLoopNT-out 23.093 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -92.4, 141.9 APE9-dihe-na -84.31, -172.93 APE8-dihe-in -81.24, 56.12 APE8-rot-in 309.48 APE67-dihe-in -74.89, -22.92 -59.56, -24.75 APE12-dist-in 9.752 APE11-dist-out 15.297 APE10-dist-out 14.399 APE9-dist-out 8.984 None None None XRAY 1.93 0.187 0.23 A 288 262 12 0 0 9 [[457, 716]] 1.0 7k0v Homo sapiens TKL_BRAF_HUMAN TKL 5.8e-84 287.7 4 267 264 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VB P15056 449 722 766.0 VQP:801 Type2 Inactive DFGout 12.34 11.701 BBAminus -167.19, -159.19 -104.12, 109.97 -117.14, 1.82 293.72, 96.78 -102.83, -58.49 in-in in 8.352 Saltbr-in 2.756 HRD-in -71.48, -47.17 73.94, -6.06 in-out-out SNCioo out-out ActLoopNT-out 14.087 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -97.2, 2.25 APE9-dihe-na 176.29, 177.5 APE8-dihe-out 64.18, 15.92 APE8-rot-in 287.72 APE67-dihe-in -68.76, -19.22 -66.09, -26.1 APE12-dist-out 14.721 APE11-dist-out 16.447 APE10-dist-out 12.441 APE9-dist-out 10.103 None None None XRAY 1.93 0.187 0.23 B 288 264 10 0 0 7 [[457, 716]] 1.0 7k0v Homo sapiens TKL_BRAF_HUMAN TKL 5.8e-84 287.7 4 267 264 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VC P15056 448 722 766.0 VQP:801 Type2 Inactive DFGout 12.415 11.312 BBAminus -149.63, -160.06 -140.65, 98.9 -96.4, 9.54 307.52, 103.4 -76.49, 147.45 in-in in 8.558 Saltbr-in 2.727 HRD-in -65.37, -52.41 83.32, -6.12 in-out-out SNCioo out-out ActLoopNT-out 18.181 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -119.69 APE8-dihe-out -98.34, 2.05 APE8-rot-in 283.36 APE67-dihe-in -63.48, -24.0 -64.49, -30.31 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.091 None None None XRAY 1.93 0.187 0.23 C 288 267 8 0 0 8 [[457, 716]] 1.0 7k0v Homo sapiens TKL_BRAF_HUMAN TKL 5.8e-84 287.7 4 267 264 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VD P15056 449 722 766.0 VQP:801 Type2 Inactive DFGout 12.377 11.418 BBAminus -149.15, -161.3 -137.52, 97.73 -97.03, 6.48 305.14, 104.21 -74.28, 146.89 in-in in 8.685 Saltbr-in 2.725 HRD-in -66.71, -47.33 78.8, -19.85 in-out-out SNCioo out-out ActLoopNT-out 18.689 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -56.48, -29.5 APE9-dihe-na -75.21, -5.78 APE8-dihe-out -116.03, -0.39 APE8-rot-in 294.97 APE67-dihe-in -63.2, -20.28 -68.0, -40.36 APE12-dist-in 10.95 APE11-dist-in 12.547 APE10-dist-out 13.523 APE9-dist-out 10.751 None None None XRAY 1.93 0.187 0.23 D 288 271 3 0 0 3 [[457, 716]] 1.0 7k0v Homo sapiens TKL_BRAF_HUMAN TKL 5.8e-84 287.7 4 267 264 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

Ligand: VQP

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name