Ligand: V4Z

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 66.7% 4AOJC
DFGin None 1 33.3% 4AOJB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR NTRK1 NTRK1_HUMAN 4AOJA 2.75 Inactive DFGin‑ABAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4AOJC 2.75 Inactive DFGin‑ABAminus in-out none-none TYR APEdihe_niiai APEdist_aaai V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4AOJB 2.75 Inactive DFGin‑None in-out none-none TYR APEdihe_nniai APEdist_aaai V4Z Type1 500 - 791 0 None None High affinity nerve growth factor receptor

Ligand: V4Z

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 66.7% 4AOJC
DFGin None 1 33.3% 4AOJB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR NTRK1 NTRK1_HUMAN 4AOJA 2.75 Inactive DFGin‑ABAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 4AOJC 2.75 Inactive DFGin‑ABAminus in-out none-none TYR APEdihe_niiai APEdist_aaai V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 4AOJB 2.75 Inactive DFGin‑None in-out none-none TYR APEdihe_nniai APEdist_aaai V4Z Type1 500 - 791 0 None None High affinity nerve growth factor receptor Homo sapiens

Ligand: V4Z

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism