Ligand: V25

Total number of chains: 4
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6QTYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CLK1 CLK1_HUMAN 6QTYA 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V25 Type1 149 - 481 0 None None Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 2VAGA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaino APEdist_oioo V25 Type1 148 - 481 0 SEP341,TPO342 None Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6TW2E 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanao APEdist_oioo V25 Type1 148 - 484 0 SEP341,TPO342 None Dual specificity protein kinase CLK1
CMGC CLK3 CLK3_HUMAN 2WU7A 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V25 Type1 135 - 482 0 None None Dual specificity protein kinase CLK3

Ligand: V25

Total number of chains: 4
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6QTYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CLK1 CLK1_HUMAN 6QTYA 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V25 Type1 149 - 481 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC CLK1 CLK1_HUMAN 2VAGA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaino APEdist_oioo V25 Type1 148 - 481 0 SEP341,TPO342 None Dual specificity protein kinase CLK1 Homo sapiens
CMGC CLK1 CLK1_HUMAN 6TW2E 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanao APEdist_oioo V25 Type1 148 - 484 0 SEP341,TPO342 None Dual specificity protein kinase CLK1 Homo sapiens
CMGC CLK3 CLK3_HUMAN 2WU7A 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V25 Type1 135 - 482 0 None None Dual specificity protein kinase CLK3 Homo sapiens

Ligand: V25

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism