Ligand: V1L

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5S7PA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL ACVR1 ACVR1_HUMAN 5S7PA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, V1L Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1

Ligand: V1L

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5S7PA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL ACVR1 ACVR1_HUMAN 5S7PA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, V1L Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens

Ligand: V1L

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism