Ligand: V0G

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 8ORMJ
DFGin None 1 33.3% 6XD3J
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK7 CDK7_HUMAN 8ORMJ 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V0G Type1 10 - 312 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9HIXJ 2.6 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii V0G Type1 10 - 312 0 None D97N Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 6XD3J 3.3 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaioi APEdist_iiii V0G Type1 10 - 312 0 SEP164 None Cyclin-dependent kinase 7

Ligand: V0G

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 8ORMJ
DFGin None 1 33.3% 6XD3J
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK7 CDK7_HUMAN 8ORMJ 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V0G Type1 10 - 312 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9HIXJ 2.6 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii V0G Type1 10 - 312 0 None D97N Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 6XD3J 3.3 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaioi APEdist_iiii V0G Type1 10 - 312 0 SEP164 None Cyclin-dependent kinase 7 Homo sapiens

Ligand: V0G

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism