Ligand: V0G

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 8ORMJ
DFGin None 1 33.3% 6XD3J
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK7 CDK7_HUMAN 8ORMJ P50613 10 312 346.0 V0G:60401 Type1 Active DFGin 6.785 15.2126 BLAminus -141.24, -179.07 57.58, 66.36 -85.75, 20.07 280.87, 76.67 -67.32, -17.72 in-in in 7.9439 Saltbr-in 2.7982 HRD-in -68.87, -49.12 65.49, 10.0 in-in-in SNCiii in-in ActLoopNT-in 2.7226 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -64.18, 162.48 APE9-dihe-na 68.43, 133.67 APE8-dihe-in -60.65, 148.97 APE8-rot-in 313.74 APE67-dihe-in -63.64, -17.24 -60.73, -41.91 APE12-dist-in 13.1843 APE11-dist-in 10.1473 APE10-dist-in 6.5345 APE9-dist-in 3.139 None None None EM 1.9 999.0 999.0 J 349.0 288.0 15 28 28 0 [[12, 295]] 1.0 8orm CMGC_CDK7_HUMAN CMGC 1.6e-78 271.7 1.0 301.0 301.0 154 155 156 158 160 41 62 66 134 136 135 137.0 195 182 177 176 175 174 173 172 171 92 Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9HIXJ P50613 10 312 346.0 V0G:60401 Type1 None DFGin 6.8855 15.3839 BLAminus -132.71, -170.75 57.98, 64.3 -89.34, 21.26 284.18, 75.08 -68.9, -17.68 in-in in 8.1948 Saltbr-in 3.2231 HRD-in -66.5, -50.94 64.89, 9.03 in-in-none SNCiin in-none ActLoopNT-in 2.8448 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -133.15, 168.02 APE9-dihe-na 68.67, 143.0 APE8-dihe-in -61.15, 147.72 APE8-rot-in 301.8 APE67-dihe-in -61.71, -29.08 -59.06, -43.61 APE12-dist-none 999.0 APE11-dist-in 11.3485 APE10-dist-in 6.9859 APE9-dist-in 3.3051 D97N None None EM 2.6 999.0 999.0 J 349.0 284.0 19 28 22 6 [[12, 295]] 1.0 9hix CMGC_CDK7_HUMAN CMGC 1.8e-78 271.6 1.0 301.0 301.0 154 155 156 158 160 41 62 66 134 136 135 137.0 195 182 177 176 175 174 173 172 171 92 Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 6XD3J P50613 10 312 346.0 V0G:401 Type1 Inactive DFGin 6.4494 15.5688 None -83.3, -65.23 -79.84, 107.47 -100.97, 25.31 275.83, 77.7 -59.79, -36.45 in-out in 7.737 Saltbr-out 3.9352 HRD-out -83.2, 82.34 -68.79, 3.46 out-in-out SNCoio in-out ActLoopNT-in 2.8333 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -91.06, 77.29 APE9-dihe-na -174.12, 154.78 APE8-dihe-in -58.68, 146.66 APE8-rot-out 59.06 APE67-dihe-in -62.31, -31.09 -65.15, -41.16 APE12-dist-in 13.6186 APE11-dist-in 11.5253 APE10-dist-in 6.1269 APE9-dist-in 3.6285 None SEP164 SEP164 EM 3.3 999.0 999.0 J 349.0 298.0 5 28 28 0 [[12, 295]] 1.0 6xd3 CMGC_CDK7_HUMAN CMGC 1.6e-78 271.7 1.0 301.0 301.0 154 155 156 158 160 41 62 66 134 136 135 137.0 195 182 177 176 175 174 173 172 171 92 Cyclin-dependent kinase 7

Ligand: V0G

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 8ORMJ
DFGin None 1 33.3% 6XD3J
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK7 CDK7_HUMAN 8ORMJ P50613 10 312 346.0 V0G:60401 Type1 Active DFGin 6.785 15.2126 BLAminus -141.24, -179.07 57.58, 66.36 -85.75, 20.07 280.87, 76.67 -67.32, -17.72 in-in in 7.9439 Saltbr-in 2.7982 HRD-in -68.87, -49.12 65.49, 10.0 in-in-in SNCiii in-in ActLoopNT-in 2.7226 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -64.18, 162.48 APE9-dihe-na 68.43, 133.67 APE8-dihe-in -60.65, 148.97 APE8-rot-in 313.74 APE67-dihe-in -63.64, -17.24 -60.73, -41.91 APE12-dist-in 13.1843 APE11-dist-in 10.1473 APE10-dist-in 6.5345 APE9-dist-in 3.139 None None None EM 1.9 999.0 999.0 J 349.0 288.0 15 28 28 0 [[12, 295]] 1.0 8orm Homo sapiens CMGC_CDK7_HUMAN CMGC 1.6e-78 271.7 1.0 301.0 301.0 154 155 156 158 160 41 62 66 134 136 135 137.0 195 182 177 176 175 174 173 172 171 92 Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9HIXJ P50613 10 312 346.0 V0G:60401 Type1 None DFGin 6.8855 15.3839 BLAminus -132.71, -170.75 57.98, 64.3 -89.34, 21.26 284.18, 75.08 -68.9, -17.68 in-in in 8.1948 Saltbr-in 3.2231 HRD-in -66.5, -50.94 64.89, 9.03 in-in-none SNCiin in-none ActLoopNT-in 2.8448 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -133.15, 168.02 APE9-dihe-na 68.67, 143.0 APE8-dihe-in -61.15, 147.72 APE8-rot-in 301.8 APE67-dihe-in -61.71, -29.08 -59.06, -43.61 APE12-dist-none 999.0 APE11-dist-in 11.3485 APE10-dist-in 6.9859 APE9-dist-in 3.3051 D97N None None EM 2.6 999.0 999.0 J 349.0 284.0 19 28 22 6 [[12, 295]] 1.0 9hix Homo sapiens CMGC_CDK7_HUMAN CMGC 1.8e-78 271.6 1.0 301.0 301.0 154 155 156 158 160 41 62 66 134 136 135 137.0 195 182 177 176 175 174 173 172 171 92 Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 6XD3J P50613 10 312 346.0 V0G:401 Type1 Inactive DFGin 6.4494 15.5688 None -83.3, -65.23 -79.84, 107.47 -100.97, 25.31 275.83, 77.7 -59.79, -36.45 in-out in 7.737 Saltbr-out 3.9352 HRD-out -83.2, 82.34 -68.79, 3.46 out-in-out SNCoio in-out ActLoopNT-in 2.8333 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -91.06, 77.29 APE9-dihe-na -174.12, 154.78 APE8-dihe-in -58.68, 146.66 APE8-rot-out 59.06 APE67-dihe-in -62.31, -31.09 -65.15, -41.16 APE12-dist-in 13.6186 APE11-dist-in 11.5253 APE10-dist-in 6.1269 APE9-dist-in 3.6285 None SEP164 SEP164 EM 3.3 999.0 999.0 J 349.0 298.0 5 28 28 0 [[12, 295]] 1.0 6xd3 Homo sapiens CMGC_CDK7_HUMAN CMGC 1.6e-78 271.7 1.0 301.0 301.0 154 155 156 158 160 41 62 66 134 136 135 137.0 195 182 177 176 175 174 173 172 171 92 Cyclin-dependent kinase 7

Ligand: V0G

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name