Ligand: TBK

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 7BCMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR DDR1 DDR1_HUMAN 7BCMA Q08345 604 909 913.0 TBK:1001 Type2 Inactive DFGout 13.0077 10.0934 BBAminus -144.68, -175.9 -143.48, 102.2 -83.62, 3.62 287.6, 81.94 81.32, -168.03 in-in in 8.6556 Saltbr-in 3.0086 HRD-in -65.71, -55.98 87.34, -19.67 in-out-in SNCioi out-in ActLoopNT-out 18.3073 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.26, 137.51 APE9-dihe-in -123.82, 128.63 APE8-dihe-in -86.21, 69.22 APE8-rot-na 27.2 APE67-dihe-in -71.43, -12.52 -62.93, -34.22 APE12-dist-na 13.4502 APE11-dist-na 10.5031 APE10-dist-na 6.2764 APE9-dist-in 7.552 None None None XRAY 2.3 0.246 0.308 A 315.0 273.0 33 30 30 0 [[610, 907]] 1.0 7bcm TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1.0 260.0 260.0 783 784 785 787 789 655 672 676 763 765 764 766.0 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7BCMB Q08345 604 911 913.0 TBK:1001 Type2 Inactive DFGout 12.8731 10.0032 BBAminus -131.16, -172.17 -135.77, 109.56 -94.04, -4.34 282.79, 103.01 90.67, -179.36 in-out in 8.3686 Saltbr-out 3.6171 HRD-in -62.88, -55.49 80.94, -21.01 out-out-in SNCooi out-in ActLoopNT-out 18.3453 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.26, 139.25 APE9-dihe-in -129.42, 124.32 APE8-dihe-in -81.31, 68.14 APE8-rot-na 36.31 APE67-dihe-in -65.99, -20.67 -66.61, -29.37 APE12-dist-na 13.2491 APE11-dist-na 10.6529 APE10-dist-na 5.9859 APE9-dist-in 7.5238 None None None XRAY 2.3 0.246 0.308 B 315.0 266.0 42 30 30 0 [[610, 907]] 1.0 7bcm TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1.0 260.0 260.0 783 784 785 787 789 655 672 676 763 765 764 766.0 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1

Ligand: TBK

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 7BCMA
DFGout None 1 33.3% 7BDOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR DDR1 DDR1_HUMAN 7BCMA Q08345 604 909 913.0 TBK:1001 Type2 Inactive DFGout 13.0077 10.0934 BBAminus -144.68, -175.9 -143.48, 102.2 -83.62, 3.62 287.6, 81.94 81.32, -168.03 in-in in 8.6556 Saltbr-in 3.0086 HRD-in -65.71, -55.98 87.34, -19.67 in-out-in SNCioi out-in ActLoopNT-out 18.3073 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.26, 137.51 APE9-dihe-in -123.82, 128.63 APE8-dihe-in -86.21, 69.22 APE8-rot-na 27.2 APE67-dihe-in -71.43, -12.52 -62.93, -34.22 APE12-dist-na 13.4502 APE11-dist-na 10.5031 APE10-dist-na 6.2764 APE9-dist-in 7.552 None None None XRAY 2.3 0.246 0.308 A 315.0 273.0 33 30 30 0 [[610, 907]] 1.0 7bcm Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1.0 260.0 260.0 783 784 785 787 789 655 672 676 763 765 764 766.0 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7BCMB Q08345 604 911 913.0 TBK:1001 Type2 Inactive DFGout 12.8731 10.0032 BBAminus -131.16, -172.17 -135.77, 109.56 -94.04, -4.34 282.79, 103.01 90.67, -179.36 in-out in 8.3686 Saltbr-out 3.6171 HRD-in -62.88, -55.49 80.94, -21.01 out-out-in SNCooi out-in ActLoopNT-out 18.3453 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.26, 139.25 APE9-dihe-in -129.42, 124.32 APE8-dihe-in -81.31, 68.14 APE8-rot-na 36.31 APE67-dihe-in -65.99, -20.67 -66.61, -29.37 APE12-dist-na 13.2491 APE11-dist-na 10.6529 APE10-dist-na 5.9859 APE9-dist-in 7.5238 None None None XRAY 2.3 0.246 0.308 B 315.0 266.0 42 30 30 0 [[610, 907]] 1.0 7bcm Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1.0 260.0 260.0 783 784 785 787 789 655 672 676 763 765 764 766.0 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
CMGC MAPK14 MK14_MOUSE 7BDOA P47811 5 353 360.0 TBK:401 Type2 Inactive DFGout 13.2743 10.6119 None -140.45, -176.17 -147.11, 100.95 -81.65, 173.27 306.65, 120.36 -120.47, 69.03 in-out in 9.678 Saltbr-out 5.5219 HRD-in -63.13, -55.95 75.66, -10.3 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 128.1 APE8-dihe-out -57.45, -51.16 APE8-rot-in 302.29 APE67-dihe-in -59.24, -31.49 -45.26, -36.63 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8124 None None None XRAY 2.7 0.241 0.287 A 361.0 332.0 17 25 13 12 [[24, 308]] 1.0 7bdo Mus musculus CMGC_MAPK14_MOUSE CMGC 2e-85 292.7 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: TBK

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 1 100.0% 7BDOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 7BDOA P47811 5 353 360.0 TBK:401 Type2 Inactive DFGout 13.2743 10.6119 None -140.45, -176.17 -147.11, 100.95 -81.65, 173.27 306.65, 120.36 -120.47, 69.03 in-out in 9.678 Saltbr-out 5.5219 HRD-in -63.13, -55.95 75.66, -10.3 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 128.1 APE8-dihe-out -57.45, -51.16 APE8-rot-in 302.29 APE67-dihe-in -59.24, -31.49 -45.26, -36.63 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8124 None None None XRAY 2.7 0.241 0.287 A 361.0 332.0 17 25 13 12 [[24, 308]] 1.0 7bdo Mus musculus CMGC_MAPK14_MOUSE CMGC 2e-85 292.7 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14