Ligand: T3B

Total number of chains: 6
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 6 100.0% 7QHGA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL LIMK1 LIMK1_HUMAN 7B8WA P53667 330 633 647.0 T3B:701 Type2 Inactive DFGout 16.666 11.493 BBAminus -108.83, 173.28 -137.19, 82.52 -63.27, -30.52 292.34, 152.89 -108.41, 12.13 out-out out 15.418 Saltbr-out 15.239 HRD-in -60.02, -54.69 66.73, -7.71 out-out-none SNCoon out-none ActLoopNT-out 4.229 ActLoopCT-none nonTYR APEdihe_aanai APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 173.73 APE8-rot-na 249.62 APE67-dihe-in -62.65, -17.18 -62.83, -26.22 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.209 0.286 A 310 279 25 0 0 25 [[339, 606]] 1.0 7b8w TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3 266 264 477 478 479 481 483 368 384 388 457 459 458 460 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WB P53667 330 632 647.0 T3B:701 Type2 Inactive DFGout 16.767 11.059 BBAminus -106.35, 172.19 -132.14, 77.15 -57.43, -29.76 284.14, 171.59 -103.49, 0.05 out-out out 15.448 Saltbr-out 15.437 HRD-in -64.64, -57.77 78.09, -18.57 out-out-none SNCoon out-none ActLoopNT-out 4.535 ActLoopCT-none nonTYR APEdihe_aanai APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 157.36 APE8-rot-na 234.58 APE67-dihe-in -57.94, -33.17 -72.5, -19.71 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.209 0.286 B 310 275 28 0 0 25 [[339, 606]] 1.0 7b8w TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3 266 264 477 478 479 481 483 368 384 388 457 459 458 460 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WC P53667 330 632 647.0 T3B:701 Type2 Inactive DFGout 16.489 11.261 BBAminus -111.78, 177.07 -146.46, 75.42 -59.24, -37.03 298.62, 151.29 -94.08, 6.16 out-out out 15.424 Saltbr-out 15.329 HRD-in -60.88, -61.88 71.56, -6.41 out-out-none SNCoon out-none ActLoopNT-out 4.33 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -76.99, 161.6 999.0, -48.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.209 0.286 C 310 276 27 0 0 26 [[339, 606]] 1.0 7b8w TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3 266 264 477 478 479 481 483 368 384 388 457 459 458 460 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WD P53667 331 632 647.0 T3B:701 Type2 Inactive DFGout 16.785 11.419 BBAminus -104.89, 177.21 -139.94, 82.99 -62.41, -30.49 296.01, 157.77 -99.63, 2.65 out-out out 15.638 Saltbr-out 15.364 HRD-in -83.91, -55.17 72.93, -9.44 out-out-none SNCoon out-none ActLoopNT-out 4.452 ActLoopCT-none nonTYR APEdihe_aanai APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -172.92 APE8-rot-na 308.11 APE67-dihe-in -63.89, -29.07 -79.57, -3.7 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.209 0.286 D 310 273 29 0 0 25 [[339, 606]] 1.0 7b8w TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3 266 264 477 478 479 481 483 368 384 388 457 459 458 460 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN 7QHGA P53671 330 632 638.0 T3B:60701 Type2 Inactive DFGout 17.106 11.746 BBAminus -120.68, -179.95 -148.07, 82.27 -63.69, -35.06 297.46, 151.72 -95.03, 6.19 out-out out 15.901 Saltbr-out 14.972 HRD-in -69.22, -58.45 80.73, -9.42 out-out-out SNCooo out-out ActLoopNT-out 4.415 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oooo APE10-dihe-na -132.96, 150.13 APE9-dihe-na 122.11, -127.07 APE8-dihe-in -121.56, 98.92 APE8-rot-na 291.42 APE67-dihe-in -67.87, -23.41 -89.26, 16.88 APE12-dist-out 19.149 APE11-dist-out 16.283 APE10-dist-out 16.046 APE9-dist-out 11.184 None None None XRAY 1.45 0.166 0.177 A 305 282 21 0 0 21 [[331, 603]] 1.0 7qhg TKL_LIMK2_HUMAN TKL 7e-77 264.5 3 266 264 468 469 470 472 474 360 376 380 448 450 449 451 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 7QHGB P53671 330 632 638.0 T3B:60701 Type2 Inactive DFGout 17.212 12.137 BBAminus -115.77, 177.7 -145.12, 83.29 -66.87, -32.88 299.11, 134.99 -99.0, 8.98 out-out out 15.637 Saltbr-out 15.229 HRD-in -68.94, -54.88 80.26, -12.53 out-out-out SNCooo out-out ActLoopNT-out 4.417 ActLoopCT-out nonTYR APEdihe_aaoao APEdist_iooo APE10-dihe-na -153.58, 152.19 APE9-dihe-na 72.86, 27.01 APE8-dihe-out 69.41, 81.19 APE8-rot-na 313.41 APE67-dihe-out -61.53, -27.57 -82.37, 89.51 APE12-dist-in 12.499 APE11-dist-out 14.623 APE10-dist-out 14.118 APE9-dist-out 12.649 None None None XRAY 1.45 0.166 0.177 B 305 281 22 0 0 22 [[331, 603]] 1.0 7qhg TKL_LIMK2_HUMAN TKL 7e-77 264.5 3 266 264 468 469 470 472 474 360 376 380 448 450 449 451 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2

Ligand: T3B

Total number of chains: 6
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 6 100.0% 7QHGA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL LIMK1 LIMK1_HUMAN 7B8WA P53667 330 633 647.0 T3B:701 Type2 Inactive DFGout 16.666 11.493 BBAminus -108.83, 173.28 -137.19, 82.52 -63.27, -30.52 292.34, 152.89 -108.41, 12.13 out-out out 15.418 Saltbr-out 15.239 HRD-in -60.02, -54.69 66.73, -7.71 out-out-none SNCoon out-none ActLoopNT-out 4.229 ActLoopCT-none nonTYR APEdihe_aanai APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 173.73 APE8-rot-na 249.62 APE67-dihe-in -62.65, -17.18 -62.83, -26.22 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.209 0.286 A 310 279 25 0 0 25 [[339, 606]] 1.0 7b8w Homo sapiens TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3 266 264 477 478 479 481 483 368 384 388 457 459 458 460 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WB P53667 330 632 647.0 T3B:701 Type2 Inactive DFGout 16.767 11.059 BBAminus -106.35, 172.19 -132.14, 77.15 -57.43, -29.76 284.14, 171.59 -103.49, 0.05 out-out out 15.448 Saltbr-out 15.437 HRD-in -64.64, -57.77 78.09, -18.57 out-out-none SNCoon out-none ActLoopNT-out 4.535 ActLoopCT-none nonTYR APEdihe_aanai APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 157.36 APE8-rot-na 234.58 APE67-dihe-in -57.94, -33.17 -72.5, -19.71 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.209 0.286 B 310 275 28 0 0 25 [[339, 606]] 1.0 7b8w Homo sapiens TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3 266 264 477 478 479 481 483 368 384 388 457 459 458 460 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WC P53667 330 632 647.0 T3B:701 Type2 Inactive DFGout 16.489 11.261 BBAminus -111.78, 177.07 -146.46, 75.42 -59.24, -37.03 298.62, 151.29 -94.08, 6.16 out-out out 15.424 Saltbr-out 15.329 HRD-in -60.88, -61.88 71.56, -6.41 out-out-none SNCoon out-none ActLoopNT-out 4.33 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -76.99, 161.6 999.0, -48.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.209 0.286 C 310 276 27 0 0 26 [[339, 606]] 1.0 7b8w Homo sapiens TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3 266 264 477 478 479 481 483 368 384 388 457 459 458 460 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WD P53667 331 632 647.0 T3B:701 Type2 Inactive DFGout 16.785 11.419 BBAminus -104.89, 177.21 -139.94, 82.99 -62.41, -30.49 296.01, 157.77 -99.63, 2.65 out-out out 15.638 Saltbr-out 15.364 HRD-in -83.91, -55.17 72.93, -9.44 out-out-none SNCoon out-none ActLoopNT-out 4.452 ActLoopCT-none nonTYR APEdihe_aanai APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -172.92 APE8-rot-na 308.11 APE67-dihe-in -63.89, -29.07 -79.57, -3.7 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.209 0.286 D 310 273 29 0 0 25 [[339, 606]] 1.0 7b8w Homo sapiens TKL_LIMK1_HUMAN TKL 4.5e-77 265.1 3 266 264 477 478 479 481 483 368 384 388 457 459 458 460 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN 7QHGA P53671 330 632 638.0 T3B:60701 Type2 Inactive DFGout 17.106 11.746 BBAminus -120.68, -179.95 -148.07, 82.27 -63.69, -35.06 297.46, 151.72 -95.03, 6.19 out-out out 15.901 Saltbr-out 14.972 HRD-in -69.22, -58.45 80.73, -9.42 out-out-out SNCooo out-out ActLoopNT-out 4.415 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oooo APE10-dihe-na -132.96, 150.13 APE9-dihe-na 122.11, -127.07 APE8-dihe-in -121.56, 98.92 APE8-rot-na 291.42 APE67-dihe-in -67.87, -23.41 -89.26, 16.88 APE12-dist-out 19.149 APE11-dist-out 16.283 APE10-dist-out 16.046 APE9-dist-out 11.184 None None None XRAY 1.45 0.166 0.177 A 305 282 21 0 0 21 [[331, 603]] 1.0 7qhg Homo sapiens TKL_LIMK2_HUMAN TKL 7e-77 264.5 3 266 264 468 469 470 472 474 360 376 380 448 450 449 451 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 7QHGB P53671 330 632 638.0 T3B:60701 Type2 Inactive DFGout 17.212 12.137 BBAminus -115.77, 177.7 -145.12, 83.29 -66.87, -32.88 299.11, 134.99 -99.0, 8.98 out-out out 15.637 Saltbr-out 15.229 HRD-in -68.94, -54.88 80.26, -12.53 out-out-out SNCooo out-out ActLoopNT-out 4.417 ActLoopCT-out nonTYR APEdihe_aaoao APEdist_iooo APE10-dihe-na -153.58, 152.19 APE9-dihe-na 72.86, 27.01 APE8-dihe-out 69.41, 81.19 APE8-rot-na 313.41 APE67-dihe-out -61.53, -27.57 -82.37, 89.51 APE12-dist-in 12.499 APE11-dist-out 14.623 APE10-dist-out 14.118 APE9-dist-out 12.649 None None None XRAY 1.45 0.166 0.177 B 305 281 22 0 0 22 [[331, 603]] 1.0 7qhg Homo sapiens TKL_LIMK2_HUMAN TKL 7e-77 264.5 3 266 264 468 469 470 472 474 360 376 380 448 450 449 451 528 516 511 510 509 508 507 506 505 406 LIM domain kinase 2

Ligand: T3B

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name