Ligand: RKD

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8X5LA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC PRKACA KAPCA_HUMAN 8X5LA 2.75 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iooo RKD Type1 17 - 351 0 SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 8X5LB 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_iioo RKD Type1 17 - 334 0 SEP339 None cAMP-dependent protein kinase catalytic subunit alpha

Ligand: RKD

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 4AXAA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PRKACA KAPCA_BOVIN 4AXAA 1.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKD Type1 15 - 351 0 TPO198,SEP339 V105T,V124A,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_HUMAN 8X5LA 2.75 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iooo RKD Type1 17 - 351 0 SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 8X5LB 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_iioo RKD Type1 17 - 334 0 SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens

Ligand: RKD

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 4AXAA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PRKACA KAPCA_BOVIN 4AXAA 1.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKD Type1 15 - 351 0 TPO198,SEP339 V105T,V124A,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus