Ligand: RCM

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 6 100.0% 4ITHB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK1 RIPK1_HUMAN 9GTGB Q13546 8 294 671.0 A1IPG:301,RCM:302 Type1,Type3 Inactive DFGout 13.8827 8.7306 BBAminus -133.16, 165.18 -135.72, 76.93 -76.72, -18.51 304.22, 175.37 -84.19, -9.82 out-out out 14.397 Saltbr-out 11.5335 HRD-in -66.92, -59.7 80.95, -9.91 out-out-out SNCooo out-out ActLoopNT-out 5.2599 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -59.54 APE8-dihe-out -101.61, -12.8 APE8-rot-out 94.63 APE67-dihe-in -61.15, -22.29 -56.15, -36.7 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.5048 None None None XRAY 2.25 0.221 0.295 B 313.0 259.0 28 41 22 19 [[17, 287]] 1.0 9gtg TKL_RIPK1_HUMAN TKL 1.5e-72 250.2 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHA Q13546 8 294 671.0 RCM:307 Type3 Inactive DFGout 14.1114 8.0418 BBAminus -124.73, 172.6 -138.48, 68.81 -68.88, -22.32 295.59, 2.39 -91.07, 2.58 out-out out 13.5983 Saltbr-out 12.9654 HRD-in -65.52, -52.94 79.64, -21.46 out-out-out SNCooo out-out ActLoopNT-out 5.1245 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 174.47 APE8-dihe-in -73.02, 143.29 APE8-rot-in 249.4 APE67-dihe-in -62.29, -27.12 -114.9, 22.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.706 C34A,C127A,C233A,C240A None None XRAY 2.25 0.222 0.247 A 294.0 247.0 40 41 22 19 [[17, 287]] 1.0 4ith TKL_RIPK1_HUMAN TKL 1.2e-72 250.6 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHB Q13546 7 294 671.0 RCM:307 Type3 Inactive DFGout 13.9111 7.8802 BBAminus -124.36, 170.84 -137.49, 67.98 -68.97, -21.27 308.9, 171.62 -88.43, 4.67 out-out out 13.6712 Saltbr-out 12.3545 HRD-in -66.08, -61.08 99.79, -41.26 out-out-out SNCooo out-out ActLoopNT-out 5.2873 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 176.33 APE8-dihe-out -80.2, -0.81 APE8-rot-out 76.21 APE67-dihe-in -69.94, -29.23 -70.53, -20.15 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.3721 C34A,C127A,C233A,C240A None None XRAY 2.25 0.222 0.247 B 294.0 270.0 18 41 29 12 [[17, 287]] 1.0 4ith TKL_RIPK1_HUMAN TKL 1.2e-72 250.6 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYA Q13546 8 294 671.0 RCM:301 Type3 Inactive DFGout 13.983 8.2219 BBAminus -123.34, 171.31 -137.95, 64.52 -61.74, -25.38 305.36, 176.3 -90.28, 0.66 out-out out 13.7522 Saltbr-out 13.2448 HRD-in -64.08, -57.67 81.97, -22.12 out-out-out SNCooo out-out ActLoopNT-out 5.2267 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -14.17 APE8-dihe-out -79.25, -21.69 APE8-rot-out 51.22 APE67-dihe-in -62.86, -31.23 -89.57, 1.5 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.8161 C34A,C127A,C233A,C240A None None XRAY 2.145 0.251 0.294 A 313.0 253.0 34 41 22 19 [[17, 287]] 1.0 9gty TKL_RIPK1_HUMAN TKL 1.5e-72 250.2 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTGA Q13546 8 294 671.0 RCM:301,A1IPG:302 Type3,Type1 Inactive DFGout 14.048 8.7331 BBAminus -120.7, 174.19 -140.11, 66.75 -72.21, -11.93 303.8, 178.39 -100.67, 0.92 out-out out 13.5004 Saltbr-out 12.1 HRD-in -70.04, -46.73 71.98, -13.03 out-out-out SNCooo out-out ActLoopNT-out 5.0995 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -38.11 APE8-dihe-out -53.85, -42.8 APE8-rot-out 59.02 APE67-dihe-in -64.33, -16.83 -85.43, -11.7 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.8595 None None None XRAY 2.25 0.221 0.295 A 313.0 259.0 28 41 22 19 [[17, 287]] 1.0 9gtg TKL_RIPK1_HUMAN TKL 1.5e-72 250.2 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYB Q13546 8 294 671.0 RCM:301,A1IKX:302 Type3,Type1 Inactive DFGout 14.1589 8.4542 BBAminus -123.21, 170.66 -136.75, 64.56 -61.45, -25.1 304.25, 174.68 -90.93, 0.86 out-out out 13.9325 Saltbr-out 13.3544 HRD-in -64.37, -58.12 82.38, -22.95 out-out-out SNCooo out-out ActLoopNT-out 5.2033 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -12.75 APE8-dihe-out -78.82, -22.72 APE8-rot-out 50.86 APE67-dihe-in -62.42, -30.84 -90.02, 1.67 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.905 C34A,C127A,C233A,C240A None None XRAY 2.145 0.251 0.294 B 313.0 259.0 28 41 22 19 [[17, 287]] 1.0 9gty TKL_RIPK1_HUMAN TKL 1.5e-72 250.2 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1

Ligand: RCM

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 6 100.0% 4ITHB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK1 RIPK1_HUMAN 9GTGB Q13546 8 294 671.0 A1IPG:301,RCM:302 Type1,Type3 Inactive DFGout 13.8827 8.7306 BBAminus -133.16, 165.18 -135.72, 76.93 -76.72, -18.51 304.22, 175.37 -84.19, -9.82 out-out out 14.397 Saltbr-out 11.5335 HRD-in -66.92, -59.7 80.95, -9.91 out-out-out SNCooo out-out ActLoopNT-out 5.2599 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -59.54 APE8-dihe-out -101.61, -12.8 APE8-rot-out 94.63 APE67-dihe-in -61.15, -22.29 -56.15, -36.7 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.5048 None None None XRAY 2.25 0.221 0.295 B 313.0 259.0 28 41 22 19 [[17, 287]] 1.0 9gtg Homo sapiens TKL_RIPK1_HUMAN TKL 1.5e-72 250.2 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHA Q13546 8 294 671.0 RCM:307 Type3 Inactive DFGout 14.1114 8.0418 BBAminus -124.73, 172.6 -138.48, 68.81 -68.88, -22.32 295.59, 2.39 -91.07, 2.58 out-out out 13.5983 Saltbr-out 12.9654 HRD-in -65.52, -52.94 79.64, -21.46 out-out-out SNCooo out-out ActLoopNT-out 5.1245 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 174.47 APE8-dihe-in -73.02, 143.29 APE8-rot-in 249.4 APE67-dihe-in -62.29, -27.12 -114.9, 22.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.706 C34A,C127A,C233A,C240A None None XRAY 2.25 0.222 0.247 A 294.0 247.0 40 41 22 19 [[17, 287]] 1.0 4ith Homo sapiens TKL_RIPK1_HUMAN TKL 1.2e-72 250.6 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHB Q13546 7 294 671.0 RCM:307 Type3 Inactive DFGout 13.9111 7.8802 BBAminus -124.36, 170.84 -137.49, 67.98 -68.97, -21.27 308.9, 171.62 -88.43, 4.67 out-out out 13.6712 Saltbr-out 12.3545 HRD-in -66.08, -61.08 99.79, -41.26 out-out-out SNCooo out-out ActLoopNT-out 5.2873 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 176.33 APE8-dihe-out -80.2, -0.81 APE8-rot-out 76.21 APE67-dihe-in -69.94, -29.23 -70.53, -20.15 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.3721 C34A,C127A,C233A,C240A None None XRAY 2.25 0.222 0.247 B 294.0 270.0 18 41 29 12 [[17, 287]] 1.0 4ith Homo sapiens TKL_RIPK1_HUMAN TKL 1.2e-72 250.6 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYA Q13546 8 294 671.0 RCM:301 Type3 Inactive DFGout 13.983 8.2219 BBAminus -123.34, 171.31 -137.95, 64.52 -61.74, -25.38 305.36, 176.3 -90.28, 0.66 out-out out 13.7522 Saltbr-out 13.2448 HRD-in -64.08, -57.67 81.97, -22.12 out-out-out SNCooo out-out ActLoopNT-out 5.2267 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -14.17 APE8-dihe-out -79.25, -21.69 APE8-rot-out 51.22 APE67-dihe-in -62.86, -31.23 -89.57, 1.5 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.8161 C34A,C127A,C233A,C240A None None XRAY 2.145 0.251 0.294 A 313.0 253.0 34 41 22 19 [[17, 287]] 1.0 9gty Homo sapiens TKL_RIPK1_HUMAN TKL 1.5e-72 250.2 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTGA Q13546 8 294 671.0 RCM:301,A1IPG:302 Type3,Type1 Inactive DFGout 14.048 8.7331 BBAminus -120.7, 174.19 -140.11, 66.75 -72.21, -11.93 303.8, 178.39 -100.67, 0.92 out-out out 13.5004 Saltbr-out 12.1 HRD-in -70.04, -46.73 71.98, -13.03 out-out-out SNCooo out-out ActLoopNT-out 5.0995 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -38.11 APE8-dihe-out -53.85, -42.8 APE8-rot-out 59.02 APE67-dihe-in -64.33, -16.83 -85.43, -11.7 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.8595 None None None XRAY 2.25 0.221 0.295 A 313.0 259.0 28 41 22 19 [[17, 287]] 1.0 9gtg Homo sapiens TKL_RIPK1_HUMAN TKL 1.5e-72 250.2 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYB Q13546 8 294 671.0 RCM:301,A1IKX:302 Type3,Type1 Inactive DFGout 14.1589 8.4542 BBAminus -123.21, 170.66 -136.75, 64.56 -61.45, -25.1 304.25, 174.68 -90.93, 0.86 out-out out 13.9325 Saltbr-out 13.3544 HRD-in -64.37, -58.12 82.38, -22.95 out-out-out SNCooo out-out ActLoopNT-out 5.2033 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -12.75 APE8-dihe-out -78.82, -22.72 APE8-rot-out 50.86 APE67-dihe-in -62.42, -30.84 -90.02, 1.67 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.905 C34A,C127A,C233A,C240A None None XRAY 2.145 0.251 0.294 B 313.0 259.0 28 41 22 19 [[17, 287]] 1.0 9gty Homo sapiens TKL_RIPK1_HUMAN TKL 1.5e-72 250.2 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1

Ligand: RCM

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name