Ligand: OQ8

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 6YG6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K7 MP2K7_HUMAN 6YG6A O14733 103 403 419.0 OQ8:60502 Type2 Inactive DFGout 16.1841 8.3099 None -139.95, -178.26 -130.53, 97.33 -80.93, -18.66 197.5, 70.15 99.84, 999.0 out-na out 11.8197 Saltbr-na 9.0572 HRD-in -74.08, -54.03 80.87, -1.6 na-none-out SNCano none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiao APEdist_nnno APE10-dihe-na 999.0, 156.96 APE9-dihe-na -153.68, 151.67 APE8-dihe-in -133.13, 149.82 APE8-rot-na 44.78 APE67-dihe-out -157.98, 122.58 -86.76, 138.16 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 20.3416 S271D,T275D None None XRAY 2.15 0.205 0.239 A 307.0 284.0 17 27 13 14 [[120, 380]] 1.0 6yg6 STE_MAP2K7_HUMAN STE 3.3e-80 275.1 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6YG6B O14733 104 403 419.0 OQ8:60504 Type2 Inactive DFGout 16.2787 8.6873 None -139.8, 179.92 -130.12, 95.85 -78.51, -14.19 197.24, 65.37 105.19, 999.0 out-na out 11.2208 Saltbr-na 7.8821 HRD-in -78.17, -53.67 81.94, -0.01 na-none-out SNCano none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiao APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 171.84 APE8-dihe-in -146.43, 151.13 APE8-rot-na 48.74 APE67-dihe-out -158.28, 125.4 -86.76, 140.34 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 20.4249 S271D,T275D None None XRAY 2.15 0.205 0.239 B 307.0 281.0 19 27 12 15 [[120, 380]] 1.0 6yg6 STE_MAP2K7_HUMAN STE 3.3e-80 275.1 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7

Ligand: OQ8

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 6YG6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K7 MP2K7_HUMAN 6YG6A O14733 103 403 419.0 OQ8:60502 Type2 Inactive DFGout 16.1841 8.3099 None -139.95, -178.26 -130.53, 97.33 -80.93, -18.66 197.5, 70.15 99.84, 999.0 out-na out 11.8197 Saltbr-na 9.0572 HRD-in -74.08, -54.03 80.87, -1.6 na-none-out SNCano none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiao APEdist_nnno APE10-dihe-na 999.0, 156.96 APE9-dihe-na -153.68, 151.67 APE8-dihe-in -133.13, 149.82 APE8-rot-na 44.78 APE67-dihe-out -157.98, 122.58 -86.76, 138.16 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 20.3416 S271D,T275D None None XRAY 2.15 0.205 0.239 A 307.0 284.0 17 27 13 14 [[120, 380]] 1.0 6yg6 Homo sapiens STE_MAP2K7_HUMAN STE 3.3e-80 275.1 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6YG6B O14733 104 403 419.0 OQ8:60504 Type2 Inactive DFGout 16.2787 8.6873 None -139.8, 179.92 -130.12, 95.85 -78.51, -14.19 197.24, 65.37 105.19, 999.0 out-na out 11.2208 Saltbr-na 7.8821 HRD-in -78.17, -53.67 81.94, -0.01 na-none-out SNCano none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiao APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 171.84 APE8-dihe-in -146.43, 151.13 APE8-rot-na 48.74 APE67-dihe-out -158.28, 125.4 -86.76, 140.34 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 20.4249 S271D,T275D None None XRAY 2.15 0.205 0.239 B 307.0 281.0 19 27 12 15 [[120, 380]] 1.0 6yg6 Homo sapiens STE_MAP2K7_HUMAN STE 3.3e-80 275.1 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7

Ligand: OQ8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name