Ligand: NKJ

Total number of chains: 4
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6OYWA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE MAP3K5 M3K5_HUMAN 6OYWA 2.603 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NKJ Type1 671 - 939 0 None T838E Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWB 2.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi NKJ Type1 671 - 940 0 None T838E Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWC 2.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi NKJ Type1 671 - 939 0 None T838E Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWD 2.603 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NKJ Type1 671 - 939 0 None T838E Mitogen-activated protein kinase kinase kinase 5

Ligand: NKJ

Total number of chains: 4
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6OYWA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE MAP3K5 M3K5_HUMAN 6OYWA 2.603 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NKJ Type1 671 - 939 0 None T838E Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP3K5 M3K5_HUMAN 6OYWB 2.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi NKJ Type1 671 - 940 0 None T838E Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP3K5 M3K5_HUMAN 6OYWC 2.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi NKJ Type1 671 - 939 0 None T838E Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP3K5 M3K5_HUMAN 6OYWD 2.603 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NKJ Type1 671 - 939 0 None T838E Mitogen-activated protein kinase kinase kinase 5 Homo sapiens

Ligand: NKJ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism