Ligand: NKJ

Total number of chains: 4
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6OYWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K5 M3K5_HUMAN 6OYWA Q99683 671 939 1374.0 NKJ:1001 Type1 Active DFGin 6.4341 14.086 BLAminus -125.84, 170.11 63.72, 92.65 -105.14, 20.43 292.62, 91.43 -65.77, -22.03 in-in in 8.8219 Saltbr-in 2.7422 HRD-in -80.43, -46.73 68.52, 12.61 in-in-in SNCiii in-in ActLoopNT-in 2.933 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.72, -53.83 APE9-dihe-na -69.9, -156.1 APE8-dihe-in -92.5, 138.42 APE8-rot-in 305.47 APE67-dihe-in -70.77, -12.46 -57.12, -50.56 APE12-dist-in 9.3372 APE11-dist-in 11.4953 APE10-dist-in 5.7726 APE9-dist-in 3.3641 T838E None None XRAY 2.603 0.21 0.255 A 294.0 261.0 8 28 23 5 [[678, 938]] 1.0 6oyw STE_MAP3K5_HUMAN STE 1.2e-80 276.6 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWB Q99683 671 940 1374.0 NKJ:1001 Type1 Inactive DFGin 6.6897 13.8676 BLAminus -122.51, 166.6 60.27, 92.71 -105.19, 18.97 297.73, 95.21 -67.14, -20.88 in-in in 8.5731 Saltbr-in 2.696 HRD-in -76.18, -44.1 70.51, 11.85 in-in-out SNCiio in-out ActLoopNT-in 3.1859 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 104.69 APE9-dihe-na -71.78, -150.4 APE8-dihe-in -87.95, 134.15 APE8-rot-in 310.76 APE67-dihe-in -70.38, -10.89 -59.89, -50.46 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.1315 APE9-dist-in 3.937 T838E None None XRAY 2.603 0.21 0.255 B 294.0 256.0 14 28 18 10 [[678, 938]] 1.0 6oyw STE_MAP3K5_HUMAN STE 1.2e-80 276.6 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWC Q99683 671 939 1374.0 NKJ:1001 Type1 Inactive DFGin 6.8217 14.1935 BLAminus -125.99, 170.88 63.72, 91.25 -105.44, 18.69 294.07, 95.01 -66.78, -18.88 in-in in 8.8295 Saltbr-in 2.6138 HRD-in -80.6, -45.91 69.98, 10.62 in-in-out SNCiio in-out ActLoopNT-in 2.8552 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -133.5, 148.17 APE9-dihe-na -70.3, -155.77 APE8-dihe-in -88.98, 138.74 APE8-rot-out 85.39 APE67-dihe-in -67.74, -14.04 -56.79, -47.02 APE12-dist-in 10.9845 APE11-dist-out 6.0323 APE10-dist-out 10.2363 APE9-dist-in 3.6751 T838E None None XRAY 2.603 0.21 0.255 C 294.0 260.0 9 28 23 5 [[678, 938]] 1.0 6oyw STE_MAP3K5_HUMAN STE 1.2e-80 276.6 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWD Q99683 671 939 1374.0 NKJ:1001 Type1 Active DFGin 6.7296 14.0996 BLAminus -126.38, 171.59 64.38, 91.17 -105.76, 19.88 291.74, 93.18 -66.55, -21.17 in-in in 8.5701 Saltbr-in 2.6149 HRD-in -79.44, -46.61 68.22, 12.5 in-in-in SNCiii in-in ActLoopNT-in 3.0809 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.59, -53.64 APE9-dihe-na -69.48, -155.47 APE8-dihe-in -94.08, 138.29 APE8-rot-in 307.43 APE67-dihe-in -70.62, -12.36 -58.47, -50.51 APE12-dist-in 9.6166 APE11-dist-in 11.1803 APE10-dist-in 5.582 APE9-dist-in 3.2492 T838E None None XRAY 2.603 0.21 0.255 D 294.0 260.0 9 28 21 7 [[678, 938]] 1.0 6oyw STE_MAP3K5_HUMAN STE 1.2e-80 276.6 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5

Ligand: NKJ

Total number of chains: 4
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6OYWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K5 M3K5_HUMAN 6OYWA Q99683 671 939 1374.0 NKJ:1001 Type1 Active DFGin 6.4341 14.086 BLAminus -125.84, 170.11 63.72, 92.65 -105.14, 20.43 292.62, 91.43 -65.77, -22.03 in-in in 8.8219 Saltbr-in 2.7422 HRD-in -80.43, -46.73 68.52, 12.61 in-in-in SNCiii in-in ActLoopNT-in 2.933 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.72, -53.83 APE9-dihe-na -69.9, -156.1 APE8-dihe-in -92.5, 138.42 APE8-rot-in 305.47 APE67-dihe-in -70.77, -12.46 -57.12, -50.56 APE12-dist-in 9.3372 APE11-dist-in 11.4953 APE10-dist-in 5.7726 APE9-dist-in 3.3641 T838E None None XRAY 2.603 0.21 0.255 A 294.0 261.0 8 28 23 5 [[678, 938]] 1.0 6oyw Homo sapiens STE_MAP3K5_HUMAN STE 1.2e-80 276.6 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWB Q99683 671 940 1374.0 NKJ:1001 Type1 Inactive DFGin 6.6897 13.8676 BLAminus -122.51, 166.6 60.27, 92.71 -105.19, 18.97 297.73, 95.21 -67.14, -20.88 in-in in 8.5731 Saltbr-in 2.696 HRD-in -76.18, -44.1 70.51, 11.85 in-in-out SNCiio in-out ActLoopNT-in 3.1859 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 104.69 APE9-dihe-na -71.78, -150.4 APE8-dihe-in -87.95, 134.15 APE8-rot-in 310.76 APE67-dihe-in -70.38, -10.89 -59.89, -50.46 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.1315 APE9-dist-in 3.937 T838E None None XRAY 2.603 0.21 0.255 B 294.0 256.0 14 28 18 10 [[678, 938]] 1.0 6oyw Homo sapiens STE_MAP3K5_HUMAN STE 1.2e-80 276.6 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWC Q99683 671 939 1374.0 NKJ:1001 Type1 Inactive DFGin 6.8217 14.1935 BLAminus -125.99, 170.88 63.72, 91.25 -105.44, 18.69 294.07, 95.01 -66.78, -18.88 in-in in 8.8295 Saltbr-in 2.6138 HRD-in -80.6, -45.91 69.98, 10.62 in-in-out SNCiio in-out ActLoopNT-in 2.8552 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -133.5, 148.17 APE9-dihe-na -70.3, -155.77 APE8-dihe-in -88.98, 138.74 APE8-rot-out 85.39 APE67-dihe-in -67.74, -14.04 -56.79, -47.02 APE12-dist-in 10.9845 APE11-dist-out 6.0323 APE10-dist-out 10.2363 APE9-dist-in 3.6751 T838E None None XRAY 2.603 0.21 0.255 C 294.0 260.0 9 28 23 5 [[678, 938]] 1.0 6oyw Homo sapiens STE_MAP3K5_HUMAN STE 1.2e-80 276.6 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYWD Q99683 671 939 1374.0 NKJ:1001 Type1 Active DFGin 6.7296 14.0996 BLAminus -126.38, 171.59 64.38, 91.17 -105.76, 19.88 291.74, 93.18 -66.55, -21.17 in-in in 8.5701 Saltbr-in 2.6149 HRD-in -79.44, -46.61 68.22, 12.5 in-in-in SNCiii in-in ActLoopNT-in 3.0809 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.59, -53.64 APE9-dihe-na -69.48, -155.47 APE8-dihe-in -94.08, 138.29 APE8-rot-in 307.43 APE67-dihe-in -70.62, -12.36 -58.47, -50.51 APE12-dist-in 9.6166 APE11-dist-in 11.1803 APE10-dist-in 5.582 APE9-dist-in 3.2492 T838E None None XRAY 2.603 0.21 0.255 D 294.0 260.0 9 28 21 7 [[678, 938]] 1.0 6oyw Homo sapiens STE_MAP3K5_HUMAN STE 1.2e-80 276.6 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5

Ligand: NKJ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name