Ligand: KAV

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 6N3LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3LA Q9P2K8 584 1002 1649.0 KAV:62501 Type2 Inactive DFGout 15.7238 8.6945 None -131.92, -171.74 -165.1, 131.81 -91.39, 999.0 282.47, 16.23 999.0, 999.0 in-in in 8.3752 Saltbr-in 3.222 HRD-in -61.96, -55.14 81.8, -15.53 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -34.98 APE8-rot-none 999.0 APE67-dihe-in -81.86, -12.43 -63.68, -11.81 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 K807A,D848N,T899A,T904A None None XRAY 2.61 0.226 0.29 A 330.0 230.0 65 46 10 36 [[277, 541], [590, 1001]] 2.0 6n3l OTHER_EIF2AK4-2_HUMAN OTHER 3.8e-45 160.5 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3LB Q9P2K8 584 1002 1649.0 KAV:62501 Type2 Inactive DFGout 15.4447 8.6193 None -134.73, -168.42 -167.35, 133.28 -92.51, 999.0 285.34, 13.72 999.0, 999.0 in-in in 8.3883 Saltbr-in 3.4825 HRD-in -61.97, -53.58 83.5, -20.28 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -31.86 APE8-rot-none 999.0 APE67-dihe-in -82.56, -10.84 -61.36, -8.92 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 K807A,D848N,T899A,T904A None None XRAY 2.61 0.226 0.29 B 330.0 227.0 68 46 10 36 [[277, 541], [590, 1001]] 2.0 6n3l OTHER_EIF2AK4-2_HUMAN OTHER 3.8e-45 160.5 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2

Ligand: KAV

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 6N3LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3LA Q9P2K8 584 1002 1649.0 KAV:62501 Type2 Inactive DFGout 15.7238 8.6945 None -131.92, -171.74 -165.1, 131.81 -91.39, 999.0 282.47, 16.23 999.0, 999.0 in-in in 8.3752 Saltbr-in 3.222 HRD-in -61.96, -55.14 81.8, -15.53 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -34.98 APE8-rot-none 999.0 APE67-dihe-in -81.86, -12.43 -63.68, -11.81 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 K807A,D848N,T899A,T904A None None XRAY 2.61 0.226 0.29 A 330.0 230.0 65 46 10 36 [[277, 541], [590, 1001]] 2.0 6n3l Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 3.8e-45 160.5 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3LB Q9P2K8 584 1002 1649.0 KAV:62501 Type2 Inactive DFGout 15.4447 8.6193 None -134.73, -168.42 -167.35, 133.28 -92.51, 999.0 285.34, 13.72 999.0, 999.0 in-in in 8.3883 Saltbr-in 3.4825 HRD-in -61.97, -53.58 83.5, -20.28 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -31.86 APE8-rot-none 999.0 APE67-dihe-in -82.56, -10.84 -61.36, -8.92 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 K807A,D848N,T899A,T904A None None XRAY 2.61 0.226 0.29 B 330.0 227.0 68 46 10 36 [[277, 541], [590, 1001]] 2.0 6n3l Homo sapiens OTHER_EIF2AK4-2_HUMAN OTHER 3.8e-45 160.5 1.0 256.0 256.0 865 866 867 869 871 619 636 640 845 847 846 848.0 925 911 906 905 904 903 902 901 900 803 eIF-2-alpha kinase GCN2

Ligand: KAV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name