Ligand: HEW

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 9ET9A
None None 1 33.3% 6Q3FA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 9ET9A 2.494 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HEW, HEW, HEW, HEW, HEW Allosteric, Type1, Allosteric, Allosteric, Allosteric 1 - 297 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ET9C 2.494 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HEW, HEW Type1, Allosteric 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6Q3FA 1.18 Inactive None‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo HEW Allosteric 1 - 298 0 None None Cyclin-dependent kinase 2

Ligand: HEW

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 9ET9A
None None 1 33.3% 6Q3FA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 9ET9A 2.494 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HEW, HEW, HEW, HEW, HEW Allosteric, Type1, Allosteric, Allosteric, Allosteric 1 - 297 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 9ET9C 2.494 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HEW, HEW Type1, Allosteric 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6Q3FA 1.18 Inactive None‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo HEW Allosteric 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens

Ligand: HEW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism