Ligand

Protein kinases in complex with HEW

Total number of genes: 1

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	2	9ET9A
None	None	1	6Q3FA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	9ET9A	2.494	Active	DFGin	BLAminus	in-in	in-in	HEW HEW HEW HEW HEW	Allosteric Type1 Allosteric Allosteric Allosteric
CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	9ET9C	2.494	Active	DFGin	BLAminus	in-in	in-in	HEW HEW	Type1 Allosteric
CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	6Q3FA	1.18	Inactive	None	None	out-out	out-out	HEW	Allosteric

Protein kinases in complex with HEW

Total number of genes: 1

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	2	9ET9A
None	None	1	6Q3FA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	9ET9A	2.494	Active	DFGin	BLAminus	in-in	in-in	HEW HEW HEW HEW HEW	Allosteric Type1 Allosteric Allosteric Allosteric
Homo sapiens	CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	9ET9C	2.494	Active	DFGin	BLAminus	in-in	in-in	HEW HEW	Type1 Allosteric
Homo sapiens	CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	6Q3FA	1.18	Inactive	None	None	out-out	out-out	HEW	Allosteric

Protein kinases in complex with HEW

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type