Ligand: FKY

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 6CZ4A
DFGout None 1 50.0% 6DKBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR NTRK1 NTRK1_HUMAN 6DKBA P04629 501 796 796.0 FKY:4000 Type1 Inactive DFGout 15.3321 10.7475 None -132.31, -154.04 -173.63, 117.2 -89.02, -138.07 293.55, 87.71 -145.33, 999.0 out-in out 10.0153 Saltbr-in 3.3428 HRD-in -63.64, -46.04 75.89, -18.83 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 136.46 APE9-dihe-in -131.13, 141.89 APE8-dihe-in -81.0, 68.63 APE8-rot-na 33.49 APE67-dihe-in -61.76, -21.1 -51.01, -39.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.2727 None None None XRAY 2.68 0.217 0.245 A 320.0 272.0 24 30 19 11 [[510, 783]] 1.0 6dkb TYR_NTRK1_HUMAN TYR 2.3e-100 341.2 2.0 260.0 259.0 667 668 669 671 673 544 560 564 647 649 648 650.0 709 697 692 691 690 689 688 687 686 590 High affinity nerve growth factor receptor
TYR PTK6 PTK6_HUMAN 6CZ4A Q13882 183 443 451.0 FKY:9001 Type2 Inactive DFGout 16.3419 10.5458 BBAminus -134.4, -153.42 -159.22, 97.32 -59.78, -30.06 275.83, 86.07 -76.44, -14.06 out-out out 14.2615 Saltbr-out 16.7027 HRD-in -80.66, -52.99 77.78, -10.26 out-out-none SNCoon out-none ActLoopNT-out 7.8349 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 66.46 APE8-rot-na 25.3 APE67-dihe-in -73.53, -14.48 -47.24, -44.25 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.5 0.203 0.209 A 264.0 257.0 4 28 24 4 [[191, 443]] 1.0 6cz4 TYR_PTK6_HUMAN TYR 3.3e-88 301.3 2.0 260.0 259.0 329 330 331 333 335 219 235 239 309 311 310 312.0 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6

Ligand: FKY

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 6CZ4A
DFGout None 1 50.0% 6DKBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR NTRK1 NTRK1_HUMAN 6DKBA P04629 501 796 796.0 FKY:4000 Type1 Inactive DFGout 15.3321 10.7475 None -132.31, -154.04 -173.63, 117.2 -89.02, -138.07 293.55, 87.71 -145.33, 999.0 out-in out 10.0153 Saltbr-in 3.3428 HRD-in -63.64, -46.04 75.89, -18.83 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 136.46 APE9-dihe-in -131.13, 141.89 APE8-dihe-in -81.0, 68.63 APE8-rot-na 33.49 APE67-dihe-in -61.76, -21.1 -51.01, -39.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.2727 None None None XRAY 2.68 0.217 0.245 A 320.0 272.0 24 30 19 11 [[510, 783]] 1.0 6dkb Homo sapiens TYR_NTRK1_HUMAN TYR 2.3e-100 341.2 2.0 260.0 259.0 667 668 669 671 673 544 560 564 647 649 648 650.0 709 697 692 691 690 689 688 687 686 590 High affinity nerve growth factor receptor
TYR PTK6 PTK6_HUMAN 6CZ4A Q13882 183 443 451.0 FKY:9001 Type2 Inactive DFGout 16.3419 10.5458 BBAminus -134.4, -153.42 -159.22, 97.32 -59.78, -30.06 275.83, 86.07 -76.44, -14.06 out-out out 14.2615 Saltbr-out 16.7027 HRD-in -80.66, -52.99 77.78, -10.26 out-out-none SNCoon out-none ActLoopNT-out 7.8349 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 66.46 APE8-rot-na 25.3 APE67-dihe-in -73.53, -14.48 -47.24, -44.25 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.5 0.203 0.209 A 264.0 257.0 4 28 24 4 [[191, 443]] 1.0 6cz4 Homo sapiens TYR_PTK6_HUMAN TYR 3.3e-88 301.3 2.0 260.0 259.0 329 330 331 333 335 219 235 239 309 311 310 312.0 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6

Ligand: FKY

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name