Ligand: EZV

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 3F5XC
DFGin BLBminus 1 33.3% 3EZVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3F5XA P24941 1 298 298.0 EZV:300 Type1.5_Back Inactive DFGin 6.264 15.1438 BLAminus -134.58, -179.48 51.7, 79.18 -97.87, 23.07 283.96, 70.29 -60.84, -38.34 in-in in 8.6882 Saltbr-in 2.691 HRD-in -75.24, -51.59 71.39, 2.05 in-in-out SNCiio in-out ActLoopNT-in 2.8085 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioi APE10-dihe-na -175.83, 160.35 APE9-dihe-na 3.68, 102.57 APE8-dihe-in -38.96, 146.61 APE8-rot-out 193.19 APE67-dihe-in -61.73, -24.77 -51.83, -42.77 APE12-dist-in 11.5028 APE11-dist-in 8.374 APE10-dist-out 8.4333 APE9-dist-in 4.0064 None None None XRAY 2.4 0.266 0.283 A 298.0 297.0 1 28 28 0 [[4, 286]] 1.0 3f5x CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3F5XC P24941 1 298 298.0 EZV:300 Type1.5_Back Inactive DFGin 6.4071 15.4598 BLAminus -135.18, 179.33 51.86, 80.85 -99.79, 26.02 279.88, 72.23 -63.21, -36.5 in-in in 8.8073 Saltbr-in 3.0658 HRD-in -71.85, -53.32 74.6, -0.68 in-in-out SNCiio in-out ActLoopNT-in 2.8196 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na 133.52, -152.44 APE9-dihe-na 7.07, 96.3 APE8-dihe-in -36.48, 145.34 APE8-rot-out 171.35 APE67-dihe-in -62.68, -23.78 -54.39, -38.57 APE12-dist-in 11.4919 APE11-dist-in 8.7993 APE10-dist-in 6.6792 APE9-dist-in 3.9337 None None None XRAY 2.4 0.266 0.283 C 298.0 298.0 0 28 28 0 [[4, 286]] 1.0 3f5x CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3EZVA P24941 1 298 298.0 EZV:300 Type1 Inactive DFGin 8.2623 15.4348 BLBminus -136.58, 166.86 64.1, 47.24 -55.25, 135.65 278.78, 70.77 -82.58, 149.84 out-out out 14.71 Saltbr-out 13.1387 HRD-in -78.98, -52.27 84.47, -21.75 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 136.2 APE9-dihe-na -72.4, 130.59 APE8-dihe-in -82.3, 130.13 APE8-rot-out 173.31 APE67-dihe-in -55.91, -25.19 -101.39, -9.07 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 18.9122 APE9-dist-out 10.6946 None None None XRAY 1.99 0.228 0.244 A 300.0 277.0 21 28 14 14 [[4, 286]] 1.0 3ezv CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: EZV

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 3F5XC
DFGin BLBminus 1 33.3% 3EZVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3F5XA P24941 1 298 298.0 EZV:300 Type1.5_Back Inactive DFGin 6.264 15.1438 BLAminus -134.58, -179.48 51.7, 79.18 -97.87, 23.07 283.96, 70.29 -60.84, -38.34 in-in in 8.6882 Saltbr-in 2.691 HRD-in -75.24, -51.59 71.39, 2.05 in-in-out SNCiio in-out ActLoopNT-in 2.8085 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioi APE10-dihe-na -175.83, 160.35 APE9-dihe-na 3.68, 102.57 APE8-dihe-in -38.96, 146.61 APE8-rot-out 193.19 APE67-dihe-in -61.73, -24.77 -51.83, -42.77 APE12-dist-in 11.5028 APE11-dist-in 8.374 APE10-dist-out 8.4333 APE9-dist-in 4.0064 None None None XRAY 2.4 0.266 0.283 A 298.0 297.0 1 28 28 0 [[4, 286]] 1.0 3f5x Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3F5XC P24941 1 298 298.0 EZV:300 Type1.5_Back Inactive DFGin 6.4071 15.4598 BLAminus -135.18, 179.33 51.86, 80.85 -99.79, 26.02 279.88, 72.23 -63.21, -36.5 in-in in 8.8073 Saltbr-in 3.0658 HRD-in -71.85, -53.32 74.6, -0.68 in-in-out SNCiio in-out ActLoopNT-in 2.8196 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na 133.52, -152.44 APE9-dihe-na 7.07, 96.3 APE8-dihe-in -36.48, 145.34 APE8-rot-out 171.35 APE67-dihe-in -62.68, -23.78 -54.39, -38.57 APE12-dist-in 11.4919 APE11-dist-in 8.7993 APE10-dist-in 6.6792 APE9-dist-in 3.9337 None None None XRAY 2.4 0.266 0.283 C 298.0 298.0 0 28 28 0 [[4, 286]] 1.0 3f5x Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3EZVA P24941 1 298 298.0 EZV:300 Type1 Inactive DFGin 8.2623 15.4348 BLBminus -136.58, 166.86 64.1, 47.24 -55.25, 135.65 278.78, 70.77 -82.58, 149.84 out-out out 14.71 Saltbr-out 13.1387 HRD-in -78.98, -52.27 84.47, -21.75 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 136.2 APE9-dihe-na -72.4, 130.59 APE8-dihe-in -82.3, 130.13 APE8-rot-out 173.31 APE67-dihe-in -55.91, -25.19 -101.39, -9.07 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 18.9122 APE9-dist-out 10.6946 None None None XRAY 1.99 0.228 0.244 A 300.0 277.0 21 28 14 14 [[4, 286]] 1.0 3ezv Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: EZV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name