Ligand: DXK

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 6FNHB
DFGin BLAminus 1 25.0% 6FNHC
DFGin BLBminus 1 25.0% 6FNKA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EPHA2 EPHA2_HUMAN 6FNHA 1.379 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DXK Type1 602 - 889 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHB 1.379 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_niiai APEdist_aaao DXK Type1 602 - 882 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHC 1.379 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan DXK Type1 600 - 890 0 None None Ephrin type-A receptor 2
TYR EPHB4 EPHB4_HUMAN 6FNKA 1.049 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DXK Type1 604 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4

Ligand: DXK

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 6FNHB
DFGin BLAminus 1 25.0% 6FNHC
DFGin BLBminus 1 25.0% 6FNKA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EPHA2 EPHA2_HUMAN 6FNHA 1.379 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DXK Type1 602 - 889 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6FNHB 1.379 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_niiai APEdist_aaao DXK Type1 602 - 882 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6FNHC 1.379 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan DXK Type1 600 - 890 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNKA 1.049 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DXK Type1 604 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens

Ligand: DXK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism