Ligand: DXK

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 6FNHB
DFGin BLAminus 1 25.0% 6FNHC
DFGin BLBminus 1 25.0% 6FNKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EPHA2 EPHA2_HUMAN 6FNHA P29317 602 889 976.0 DXK:1001 Type1 Inactive DFGin 6.0291 15.2866 ABAminus -132.89, -13.6 -114.29, 112.91 -120.16, 34.85 297.73, 92.28 -68.77, 147.18 in-in in 8.5707 Saltbr-in 2.5241 HRD-in -71.64, -49.56 77.94, -13.05 in-out-in SNCioi out-in ActLoopNT-out 10.9018 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.64, 136.2 APE9-dihe-in -91.95, 112.57 APE8-dihe-in -77.45, 142.7 APE8-rot-na 28.74 APE67-dihe-in -60.57, -18.72 -57.08, -38.55 APE12-dist-na 999.0 APE11-dist-na 8.3826 APE10-dist-na 12.3766 APE9-dist-in 5.4468 None None None XRAY 1.379 0.206 0.221 A 306.0 277.0 11 31 21 10 [[613, 873]] 1.0 6fnh TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHB P29317 602 882 976.0 DXK:1001 Type1 Inactive DFGin 5.3484 15.0683 ABAminus -133.93, -15.74 -121.25, 119.84 -118.06, 28.52 301.16, 87.41 -78.43, -76.5 in-in in 8.2525 Saltbr-in 2.3405 HRD-in -74.5, -47.84 76.45, -12.42 in-out-out SNCioo out-out ActLoopNT-out 6.8125 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 153.72 APE9-dihe-in -66.55, 140.49 APE8-dihe-in -67.49, 153.9 APE8-rot-na 28.58 APE67-dihe-in -75.86, -2.19 -123.09, -16.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.2475 APE9-dist-out 8.9534 None None None XRAY 1.379 0.206 0.221 B 306.0 271.0 10 31 24 7 [[613, 873]] 1.0 6fnh TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHC P29317 600 890 976.0 DXK:1001 Type1 None DFGin 6.0999 15.0776 BLAminus -136.98, -166.98 54.47, 77.28 -106.75, 37.52 303.15, 87.48 -109.85, 171.74 in-in in 8.5229 Saltbr-in 2.9729 HRD-in -71.56, -48.37 75.35, -10.7 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 34.12 APE8-rot-na 34.55 APE67-dihe-in -53.44, -22.38 -49.0, -43.37 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.379 0.206 0.221 C 306.0 270.0 21 31 12 19 [[613, 873]] 1.0 6fnh TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR EPHB4 EPHB4_HUMAN 6FNKA P54760 604 889 987.0 DXK:1001 Type1 Inactive DFGin 5.785 15.4016 BLBminus -132.34, -179.48 79.05, 78.64 -110.02, 142.82 291.49, 104.76 170.31, 139.89 in-in in 8.0725 Saltbr-in 2.8728 HRD-in -75.87, -49.11 78.1, -14.8 in-out-in SNCioi out-in ActLoopNT-out 9.8926 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -81.14, 155.16 APE9-dihe-in -55.72, 125.74 APE8-dihe-in -77.88, 85.95 APE8-rot-na 29.38 APE67-dihe-in -64.24, -19.7 -51.66, -47.73 APE12-dist-na 999.0 APE11-dist-na 11.556 APE10-dist-na 14.9818 APE9-dist-in 6.4163 Y774E,A803V,V870I None None XRAY 1.049 0.196 0.22 A 297.0 274.0 12 33 21 12 [[615, 876]] 1.0 6fnk TYR_EPHB4_HUMAN TYR 4.2e-105 356.7 2.0 261.0 260.0 757 758 759 761 763 647 664 668 737 739 738 740.0 802 790 785 784 783 782 781 780 779 694 Ephrin type-B receptor 4

Ligand: DXK

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 6FNHB
DFGin BLAminus 1 25.0% 6FNHC
DFGin BLBminus 1 25.0% 6FNKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EPHA2 EPHA2_HUMAN 6FNHA P29317 602 889 976.0 DXK:1001 Type1 Inactive DFGin 6.0291 15.2866 ABAminus -132.89, -13.6 -114.29, 112.91 -120.16, 34.85 297.73, 92.28 -68.77, 147.18 in-in in 8.5707 Saltbr-in 2.5241 HRD-in -71.64, -49.56 77.94, -13.05 in-out-in SNCioi out-in ActLoopNT-out 10.9018 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.64, 136.2 APE9-dihe-in -91.95, 112.57 APE8-dihe-in -77.45, 142.7 APE8-rot-na 28.74 APE67-dihe-in -60.57, -18.72 -57.08, -38.55 APE12-dist-na 999.0 APE11-dist-na 8.3826 APE10-dist-na 12.3766 APE9-dist-in 5.4468 None None None XRAY 1.379 0.206 0.221 A 306.0 277.0 11 31 21 10 [[613, 873]] 1.0 6fnh Homo sapiens TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHB P29317 602 882 976.0 DXK:1001 Type1 Inactive DFGin 5.3484 15.0683 ABAminus -133.93, -15.74 -121.25, 119.84 -118.06, 28.52 301.16, 87.41 -78.43, -76.5 in-in in 8.2525 Saltbr-in 2.3405 HRD-in -74.5, -47.84 76.45, -12.42 in-out-out SNCioo out-out ActLoopNT-out 6.8125 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 153.72 APE9-dihe-in -66.55, 140.49 APE8-dihe-in -67.49, 153.9 APE8-rot-na 28.58 APE67-dihe-in -75.86, -2.19 -123.09, -16.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.2475 APE9-dist-out 8.9534 None None None XRAY 1.379 0.206 0.221 B 306.0 271.0 10 31 24 7 [[613, 873]] 1.0 6fnh Homo sapiens TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHC P29317 600 890 976.0 DXK:1001 Type1 None DFGin 6.0999 15.0776 BLAminus -136.98, -166.98 54.47, 77.28 -106.75, 37.52 303.15, 87.48 -109.85, 171.74 in-in in 8.5229 Saltbr-in 2.9729 HRD-in -71.56, -48.37 75.35, -10.7 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 34.12 APE8-rot-na 34.55 APE67-dihe-in -53.44, -22.38 -49.0, -43.37 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.379 0.206 0.221 C 306.0 270.0 21 31 12 19 [[613, 873]] 1.0 6fnh Homo sapiens TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR EPHB4 EPHB4_HUMAN 6FNKA P54760 604 889 987.0 DXK:1001 Type1 Inactive DFGin 5.785 15.4016 BLBminus -132.34, -179.48 79.05, 78.64 -110.02, 142.82 291.49, 104.76 170.31, 139.89 in-in in 8.0725 Saltbr-in 2.8728 HRD-in -75.87, -49.11 78.1, -14.8 in-out-in SNCioi out-in ActLoopNT-out 9.8926 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -81.14, 155.16 APE9-dihe-in -55.72, 125.74 APE8-dihe-in -77.88, 85.95 APE8-rot-na 29.38 APE67-dihe-in -64.24, -19.7 -51.66, -47.73 APE12-dist-na 999.0 APE11-dist-na 11.556 APE10-dist-na 14.9818 APE9-dist-in 6.4163 Y774E,A803V,V870I None None XRAY 1.049 0.196 0.22 A 297.0 274.0 12 33 21 12 [[615, 876]] 1.0 6fnk Homo sapiens TYR_EPHB4_HUMAN TYR 4.2e-105 356.7 2.0 261.0 260.0 757 758 759 761 763 647 664 668 737 739 738 740.0 802 790 785 784 783 782 781 780 779 694 Ephrin type-B receptor 4

Ligand: DXK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name