Ligand: CK7

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 40.0% 2WEVA
DFGinter BABtrans 2 40.0% 4B9DB
None None 1 20.0% 1PXOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2WEVA P24941 1 296 298.0 CK7:1297 Type1 Inactive DFGin 6.5437 15.198 BLAminus -137.41, 168.51 60.01, 89.74 -102.99, 17.97 279.57, 71.74 -57.11, -35.26 in-in in 8.5107 Saltbr-in 2.8462 HRD-in -69.59, -48.84 79.69, -15.41 in-in-out SNCiio in-out ActLoopNT-in 2.8843 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oioi APE10-dihe-na -105.15, 11.47 APE9-dihe-na -89.16, -44.89 APE8-dihe-out 143.37, 137.63 APE8-rot-out 228.7 APE67-dihe-in -61.17, -29.84 -80.46, -51.97 APE12-dist-out 14.0992 APE11-dist-in 11.4338 APE10-dist-out 8.1807 APE9-dist-in 5.0843 None None None XRAY 2.3 0.19 0.243 A 298.0 296.0 0 28 28 0 [[4, 286]] 1.0 2wev CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2WEVC P24941 1 297 298.0 CK7:1298 Type1 Inactive DFGin 6.5504 15.195 BLAminus -133.81, 172.14 61.33, 84.34 -99.44, 26.27 283.39, 69.9 -63.87, -37.78 in-in in 8.1432 Saltbr-in 2.4329 HRD-in -72.76, -51.33 81.44, -12.38 in-in-out SNCiio in-out ActLoopNT-in 2.8562 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -100.11, 130.34 APE9-dihe-na -149.09, 144.26 APE8-dihe-in -80.58, 128.5 APE8-rot-out 70.59 APE67-dihe-in -55.73, -32.73 -97.58, -7.58 APE12-dist-out 14.8483 APE11-dist-in 9.707 APE10-dist-out 12.3614 APE9-dist-out 9.1805 None None None XRAY 2.3 0.19 0.243 C 298.0 297.0 0 28 28 0 [[4, 286]] 1.0 2wev CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1PXOA P24941 1 298 298.0 CK7:500 Type1 Inactive None 11.5667 18.2818 None -110.76, 143.93 77.57, 24.97 -67.83, 134.31 244.11, 100.76 81.87, -11.45 out-out out 14.8377 Saltbr-out 18.679 HRD-in -91.02, -53.1 76.42, -22.91 out-out-out SNCooo out-out ActLoopNT-out 5.7219 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -132.43, 155.5 APE9-dihe-na -56.3, 174.32 APE8-dihe-in -103.47, 109.63 APE8-rot-out 181.49 APE67-dihe-in -54.18, -30.19 -68.46, -22.69 APE12-dist-out 20.782 APE11-dist-out 16.7083 APE10-dist-out 16.6688 APE9-dist-out 8.5267 None None None XRAY 1.96 0.22 0.235 A 298.0 294.0 4 28 28 0 [[4, 286]] 1.0 1pxo CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
NEK NEK1 NEK1_HUMAN 4B9DA Q96PY6 1 284 1258.0 CK7:61285 Type1 Inactive DFGinter 10.3047 6.0798 BABtrans -64.94, 139.98 -87.18, -44.3 -54.24, 126.06 193.16, 81.64 121.24, -18.42 out-none out 11.5396 Saltbr-none 999.0 HRD-out -117.2, 113.34 -81.68, 1.37 none-out-out SNCnoo out-out ActLoopNT-out 5.1643 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -97.21, -40.86 APE9-dihe-na -102.37, -129.43 APE8-dihe-in -86.61, 121.95 APE8-rot-in 319.16 APE67-dihe-in -71.65, -10.17 -95.47, -0.6 APE12-dist-out 16.1509 APE11-dist-out 20.7765 APE10-dist-out 18.7739 APE9-dist-out 10.6781 T162A None None XRAY 1.9 0.196 0.222 A 350.0 278.0 6 28 28 0 [[4, 258]] 1.0 4b9d NEK_NEK1_HUMAN NEK 2e-117 397.3 1.0 256.0 256.0 145 146 147 149 151 33 51 55 125 127 126 128.0 185 173 168 167 166 165 164 163 162 81 Serine/threonine-protein kinase Nek1
NEK NEK1 NEK1_HUMAN 4B9DB Q96PY6 1 284 1258.0 CK7:61285 Type1 Inactive DFGinter 10.476 6.1482 BABtrans -65.92, 139.98 -87.45, -46.22 -48.38, 128.7 190.39, 78.79 118.23, -19.27 out-out out 11.6653 Saltbr-out 11.6088 HRD-out -108.39, 113.36 -82.3, 1.28 out-out-out SNCooo out-out ActLoopNT-out 5.0611 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -82.88, -40.18 APE9-dihe-na -104.73, -128.22 APE8-dihe-in -88.79, 124.64 APE8-rot-in 318.31 APE67-dihe-in -72.39, -9.41 -95.66, -1.52 APE12-dist-out 16.1358 APE11-dist-out 20.6896 APE10-dist-out 18.6729 APE9-dist-out 10.7019 T162A None None XRAY 1.9 0.196 0.222 B 350.0 279.0 5 28 28 0 [[4, 258]] 1.0 4b9d NEK_NEK1_HUMAN NEK 2e-117 397.3 1.0 256.0 256.0 145 146 147 149 151 33 51 55 125 127 126 128.0 185 173 168 167 166 165 164 163 162 81 Serine/threonine-protein kinase Nek1

Ligand: CK7

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 40.0% 2WEVA
DFGinter BABtrans 2 40.0% 4B9DB
None None 1 20.0% 1PXOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2WEVA P24941 1 296 298.0 CK7:1297 Type1 Inactive DFGin 6.5437 15.198 BLAminus -137.41, 168.51 60.01, 89.74 -102.99, 17.97 279.57, 71.74 -57.11, -35.26 in-in in 8.5107 Saltbr-in 2.8462 HRD-in -69.59, -48.84 79.69, -15.41 in-in-out SNCiio in-out ActLoopNT-in 2.8843 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oioi APE10-dihe-na -105.15, 11.47 APE9-dihe-na -89.16, -44.89 APE8-dihe-out 143.37, 137.63 APE8-rot-out 228.7 APE67-dihe-in -61.17, -29.84 -80.46, -51.97 APE12-dist-out 14.0992 APE11-dist-in 11.4338 APE10-dist-out 8.1807 APE9-dist-in 5.0843 None None None XRAY 2.3 0.19 0.243 A 298.0 296.0 0 28 28 0 [[4, 286]] 1.0 2wev Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2WEVC P24941 1 297 298.0 CK7:1298 Type1 Inactive DFGin 6.5504 15.195 BLAminus -133.81, 172.14 61.33, 84.34 -99.44, 26.27 283.39, 69.9 -63.87, -37.78 in-in in 8.1432 Saltbr-in 2.4329 HRD-in -72.76, -51.33 81.44, -12.38 in-in-out SNCiio in-out ActLoopNT-in 2.8562 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -100.11, 130.34 APE9-dihe-na -149.09, 144.26 APE8-dihe-in -80.58, 128.5 APE8-rot-out 70.59 APE67-dihe-in -55.73, -32.73 -97.58, -7.58 APE12-dist-out 14.8483 APE11-dist-in 9.707 APE10-dist-out 12.3614 APE9-dist-out 9.1805 None None None XRAY 2.3 0.19 0.243 C 298.0 297.0 0 28 28 0 [[4, 286]] 1.0 2wev Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1PXOA P24941 1 298 298.0 CK7:500 Type1 Inactive None 11.5667 18.2818 None -110.76, 143.93 77.57, 24.97 -67.83, 134.31 244.11, 100.76 81.87, -11.45 out-out out 14.8377 Saltbr-out 18.679 HRD-in -91.02, -53.1 76.42, -22.91 out-out-out SNCooo out-out ActLoopNT-out 5.7219 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -132.43, 155.5 APE9-dihe-na -56.3, 174.32 APE8-dihe-in -103.47, 109.63 APE8-rot-out 181.49 APE67-dihe-in -54.18, -30.19 -68.46, -22.69 APE12-dist-out 20.782 APE11-dist-out 16.7083 APE10-dist-out 16.6688 APE9-dist-out 8.5267 None None None XRAY 1.96 0.22 0.235 A 298.0 294.0 4 28 28 0 [[4, 286]] 1.0 1pxo Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
NEK NEK1 NEK1_HUMAN 4B9DA Q96PY6 1 284 1258.0 CK7:61285 Type1 Inactive DFGinter 10.3047 6.0798 BABtrans -64.94, 139.98 -87.18, -44.3 -54.24, 126.06 193.16, 81.64 121.24, -18.42 out-none out 11.5396 Saltbr-none 999.0 HRD-out -117.2, 113.34 -81.68, 1.37 none-out-out SNCnoo out-out ActLoopNT-out 5.1643 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -97.21, -40.86 APE9-dihe-na -102.37, -129.43 APE8-dihe-in -86.61, 121.95 APE8-rot-in 319.16 APE67-dihe-in -71.65, -10.17 -95.47, -0.6 APE12-dist-out 16.1509 APE11-dist-out 20.7765 APE10-dist-out 18.7739 APE9-dist-out 10.6781 T162A None None XRAY 1.9 0.196 0.222 A 350.0 278.0 6 28 28 0 [[4, 258]] 1.0 4b9d Homo sapiens NEK_NEK1_HUMAN NEK 2e-117 397.3 1.0 256.0 256.0 145 146 147 149 151 33 51 55 125 127 126 128.0 185 173 168 167 166 165 164 163 162 81 Serine/threonine-protein kinase Nek1
NEK NEK1 NEK1_HUMAN 4B9DB Q96PY6 1 284 1258.0 CK7:61285 Type1 Inactive DFGinter 10.476 6.1482 BABtrans -65.92, 139.98 -87.45, -46.22 -48.38, 128.7 190.39, 78.79 118.23, -19.27 out-out out 11.6653 Saltbr-out 11.6088 HRD-out -108.39, 113.36 -82.3, 1.28 out-out-out SNCooo out-out ActLoopNT-out 5.0611 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -82.88, -40.18 APE9-dihe-na -104.73, -128.22 APE8-dihe-in -88.79, 124.64 APE8-rot-in 318.31 APE67-dihe-in -72.39, -9.41 -95.66, -1.52 APE12-dist-out 16.1358 APE11-dist-out 20.6896 APE10-dist-out 18.6729 APE9-dist-out 10.7019 T162A None None XRAY 1.9 0.196 0.222 B 350.0 279.0 5 28 28 0 [[4, 258]] 1.0 4b9d Homo sapiens NEK_NEK1_HUMAN NEK 2e-117 397.3 1.0 256.0 256.0 145 146 147 149 151 33 51 55 125 127 126 128.0 185 173 168 167 166 165 164 163 162 81 Serine/threonine-protein kinase Nek1

Ligand: CK7

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name