Ligand: C92

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 3CPBB
DFGout None 1 50.0% 3CPBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KDR VGFR2_HUMAN 3CPBB P35968 820 1165 1356.0 C92:60002 Type1 Inactive DFGout 15.47 9.8976 BBAminus -145.95, -173.33 -148.66, 122.86 -90.71, -55.39 280.65, 93.5 148.13, 999.0 in-in in 7.4662 Saltbr-in 2.7434 HRD-in -84.85, -49.1 84.19, -23.3 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -49.62 APE8-dihe-out -64.93, -12.78 APE8-rot-na 24.8 APE67-dihe-in -63.19, -14.98 -60.0, -29.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.3633 C817A,V916T,E990V PTR1054,PTR1059 PTR1054,PTR1059 XRAY 2.7 0.224 0.286 B 314.0 263.0 33 30 12 18 [[834, 1162]] 1.0 3cpb TYR_KDR_HUMAN TYR 2.8e-100 340.9 1.0 260.0 260.0 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028.0 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CPBA P35968 819 1171 1356.0 C92:60001 Type2 Inactive DFGout 15.3326 9.7507 None -143.96, -172.89 -147.19, 119.38 -89.94, 999.0 278.49, 101.53 999.0, 999.0 in-in in 7.7633 Saltbr-in 3.5846 HRD-in -60.85, -44.16 62.59, 3.77 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.93 APE8-dihe-out -45.12, -28.83 APE8-rot-na 328.95 APE67-dihe-in -65.36, -7.17 -53.29, -33.68 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.351 C817A,V916T,E990V PTR1054,PTR1059 PTR1054,PTR1059 XRAY 2.7 0.224 0.286 A 314.0 278.0 25 30 11 19 [[834, 1162]] 1.0 3cpb TYR_KDR_HUMAN TYR 2.8e-100 340.9 1.0 260.0 260.0 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028.0 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2

Ligand: C92

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 3CPBB
DFGout None 1 50.0% 3CPBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KDR VGFR2_HUMAN 3CPBB P35968 820 1165 1356.0 C92:60002 Type1 Inactive DFGout 15.47 9.8976 BBAminus -145.95, -173.33 -148.66, 122.86 -90.71, -55.39 280.65, 93.5 148.13, 999.0 in-in in 7.4662 Saltbr-in 2.7434 HRD-in -84.85, -49.1 84.19, -23.3 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -49.62 APE8-dihe-out -64.93, -12.78 APE8-rot-na 24.8 APE67-dihe-in -63.19, -14.98 -60.0, -29.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.3633 C817A,V916T,E990V PTR1054,PTR1059 PTR1054,PTR1059 XRAY 2.7 0.224 0.286 B 314.0 263.0 33 30 12 18 [[834, 1162]] 1.0 3cpb Homo sapiens TYR_KDR_HUMAN TYR 2.8e-100 340.9 1.0 260.0 260.0 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028.0 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CPBA P35968 819 1171 1356.0 C92:60001 Type2 Inactive DFGout 15.3326 9.7507 None -143.96, -172.89 -147.19, 119.38 -89.94, 999.0 278.49, 101.53 999.0, 999.0 in-in in 7.7633 Saltbr-in 3.5846 HRD-in -60.85, -44.16 62.59, 3.77 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.93 APE8-dihe-out -45.12, -28.83 APE8-rot-na 328.95 APE67-dihe-in -65.36, -7.17 -53.29, -33.68 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.351 C817A,V916T,E990V PTR1054,PTR1059 PTR1054,PTR1059 XRAY 2.7 0.224 0.286 A 314.0 278.0 25 30 11 19 [[834, 1162]] 1.0 3cpb Homo sapiens TYR_KDR_HUMAN TYR 2.8e-100 340.9 1.0 260.0 260.0 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028.0 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2

Ligand: C92

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name