Ligand: BI9

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 6BQLA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK CAMKK2 KKCC2_HUMAN 6BQLA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BI9 Type1 161 - 448 0 None None Calcium/calmodulin-dependent protein kinase kinase 2

Ligand: BI9

Total number of chains: 4
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 4D58B
DFGin BLAminus 1 25.0% 6BQLA
DFGin None 1 25.0% 2JKKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR PTK2 FAK1_CHICK 4D4SB 2.0 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D58B 1.95 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_nniai APEdist_aaao BI9 Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 2JKKA 2.0 Inactive DFGin‑None in-in out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 413 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
CAMK CAMKK2 KKCC2_HUMAN 6BQLA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BI9 Type1 161 - 448 0 None None Calcium/calmodulin-dependent protein kinase kinase 2 Homo sapiens

Ligand: BI9

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 66.7% 4D58B
DFGin None 1 33.3% 2JKKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR PTK2 FAK1_CHICK 4D4SB 2.0 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D58B 1.95 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_nniai APEdist_aaao BI9 Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 2JKKA 2.0 Inactive DFGin‑None in-in out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 413 - 684 0 None None Focal adhesion kinase 1 Gallus gallus