Ligand: AQ5

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5OTFA
DFGin None 1 50.0% 9BRFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC CDC42BPB MRCKB_HUMAN 5OTFA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AQ5 Type1 2 - 417 0 None None Serine/threonine-protein kinase MRCK beta
AGC GRK5 GRK5_HUMAN 9BRFA 2.84 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AQ5 Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5

Ligand: AQ5

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5OTFA
DFGin None 1 50.0% 9BRFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC CDC42BPB MRCKB_HUMAN 5OTFA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AQ5 Type1 2 - 417 0 None None Serine/threonine-protein kinase MRCK beta Homo sapiens
AGC GRK5 GRK5_HUMAN 9BRFA 2.84 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AQ5 Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens

Ligand: AQ5

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism