Ligand: AM6

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 100.0% 3BYUA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR LCK LCK_HUMAN 3BYUA 2.3 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nioao APEdist_aaai AM6 Type2 231 - 501 0 None None Tyrosine-protein kinase Lck

Ligand: AM6

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 100.0% 3BYUA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR LCK LCK_HUMAN 3BYUA 2.3 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nioao APEdist_aaai AM6 Type2 231 - 501 0 None None Tyrosine-protein kinase Lck Homo sapiens

Ligand: AM6

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism