Ligand: A1N

Total number of chains: 6
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% 8TZGA
DFGin None 2 33.3% 8TZHA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK CHEK1 CHK1_HUMAN 5OPBA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
TKL LRRK2 LRRK2_HUMAN 8TXZA 3.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1334 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZGA 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1333 - 2522 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZCA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1333 - 2522 0 None G2019S Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZHA 3.9 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni A1N Type1 627 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 9CHOA 7.8 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni A1N Type1 543 - 2527 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2

Ligand: A1N

Total number of chains: 6
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% 8TZGA
DFGin None 2 33.3% 8TZHA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK CHEK1 CHK1_HUMAN 5OPBA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TXZA 3.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1334 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZGA 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1333 - 2522 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZCA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1333 - 2522 0 None G2019S Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZHA 3.9 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni A1N Type1 627 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 9CHOA 7.8 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni A1N Type1 543 - 2527 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens

Ligand: A1N

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism