Ligand: A1ESP

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 4 100.0% 9VLJA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 9VLJA P11362 458 764 822.0 A1ESP:60801 Type1 Inactive DFGin 5.013 13.482 BLAplus DFGAsp-rot-out -101.6556, 162.8979 68.1829, 15.7616 292.8679, -12.1762 -69.4938, -21.4001 54.3088, 87.8099 -95.6653, 5.3023 in-in in 8.349 Saltbr-in 2.913 HRD-in -76.8347, -51.5169 81.4228, -11.978 in-out-out SNCioo out-out ActLoopNT-out 7.49 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -89.9843, 148.5943 APE9-dihe-in -105.7216, 94.2592 APE8-dihe-out -61.964, -11.1557 APE8-rot-na 15.5417 APE67-dihe-in -73.0319, -8.5438 -56.6368, -27.0121 APE12-dist-na 17.316 APE11-dist-na 19.709 APE10-dist-na 16.895 APE9-dist-out 11.062 None None None XRAY 1.81 0.178 0.215 A 310 307 0 0 0 0 [[478, 756]] 1.0 9vlj TYR_FGFR1_HUMAN TYR 2.2e-104 354.4 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9VLJB P11362 458 763 822.0 A1ESP:60801 Type1 Inactive DFGin 5.065 13.052 BLAplus DFGAsp-rot-out -103.8746, 165.3309 65.3229, 23.7673 291.1386, -21.5424 -75.1064, -24.7679 55.1733, 87.2749 -87.5574, 6.4886 in-in in 8.017 Saltbr-in 2.961 HRD-in -77.9283, -53.0516 78.9452, -9.7343 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -78.7626, 132.6318 APE9-dihe-in -92.3802, 89.329 APE8-dihe-out -61.9568, -18.6752 APE8-rot-na 331.4884 APE67-dihe-in -75.6378, 0.4646 -57.8192, -29.8755 APE12-dist-na 17.219 APE11-dist-na 19.703 APE10-dist-na 16.309 APE9-dist-out 11.24 None None None XRAY 1.81 0.178 0.215 B 310 286 20 0 0 7 [[478, 756]] 1.0 9vlj TYR_FGFR1_HUMAN TYR 2.2e-104 354.4 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 9VLMA P21802 465 763 821.0 A1ESP:801 Type1 Inactive DFGin 5.102 13.624 BLAplus DFGAsp-rot-out -113.8738, 164.4131 61.8369, 25.9143 287.6864, -4.7727 -76.2414, -15.1751 56.6026, 88.5713 -104.9967, 9.8607 in-in in 8.238 Saltbr-in 3.334 HRD-in -72.5637, -49.4303 74.5853, -6.4272 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -150.2825, 156.7344 APE9-dihe-in -118.9012, 103.5063 APE8-dihe-out -45.5188, -35.2148 APE8-rot-na 332.6996 APE67-dihe-in -71.8118, -9.6131 -46.6328, -35.6902 APE12-dist-na 14.669 APE11-dist-na 18.736 APE10-dist-na 16.645 APE9-dist-out 10.902 None None None XRAY 2.26 0.209 0.254 A 303 278 21 0 0 12 [[481, 759]] 1.0 9vlm TYR_FGFR2_HUMAN TYR 2.3e-104 354.3 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9VLMB P21802 465 763 821.0 A1ESP:801 Type1 Inactive DFGin 5.016 13.586 BLAplus DFGAsp-rot-out -113.2535, 167.4941 63.9716, 27.2042 271.1868, 47.8752 -84.2123, -19.3285 61.5314, 87.6792 -99.6038, 23.5029 in-in in 8.284 Saltbr-in 2.775 HRD-in -87.1597, -52.1506 75.5177, -0.0448 in-out-none SNCion out-none ActLoopNT-out 7.333 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -73.2396 APE8-dihe-in -86.5555, 73.4116 APE8-rot-na 28.8959 APE67-dihe-in -71.0526, -10.1419 -47.7361, -46.61 APE12-dist-na 14.942 APE11-dist-na 18.363 APE10-dist-na 999.0 APE9-dist-in 7.856 None None None XRAY 2.26 0.209 0.254 B 303 280 19 0 0 12 [[481, 759]] 1.0 9vlm TYR_FGFR2_HUMAN TYR 2.3e-104 354.3 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

Ligand: A1ESP

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 4 100.0% 9VLJA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 9VLJA P11362 458 764 822.0 A1ESP:60801 Type1 Inactive DFGin 5.013 13.482 BLAplus DFGAsp-rot-out -101.6556, 162.8979 68.1829, 15.7616 292.8679, -12.1762 -69.4938, -21.4001 54.3088, 87.8099 -95.6653, 5.3023 in-in in 8.349 Saltbr-in 2.913 HRD-in -76.8347, -51.5169 81.4228, -11.978 in-out-out SNCioo out-out ActLoopNT-out 7.49 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -89.9843, 148.5943 APE9-dihe-in -105.7216, 94.2592 APE8-dihe-out -61.964, -11.1557 APE8-rot-na 15.5417 APE67-dihe-in -73.0319, -8.5438 -56.6368, -27.0121 APE12-dist-na 17.316 APE11-dist-na 19.709 APE10-dist-na 16.895 APE9-dist-out 11.062 None None None XRAY 1.81 0.178 0.215 A 310 307 0 0 0 0 [[478, 756]] 1.0 9vlj Homo sapiens TYR_FGFR1_HUMAN TYR 2.2e-104 354.4 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9VLJB P11362 458 763 822.0 A1ESP:60801 Type1 Inactive DFGin 5.065 13.052 BLAplus DFGAsp-rot-out -103.8746, 165.3309 65.3229, 23.7673 291.1386, -21.5424 -75.1064, -24.7679 55.1733, 87.2749 -87.5574, 6.4886 in-in in 8.017 Saltbr-in 2.961 HRD-in -77.9283, -53.0516 78.9452, -9.7343 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -78.7626, 132.6318 APE9-dihe-in -92.3802, 89.329 APE8-dihe-out -61.9568, -18.6752 APE8-rot-na 331.4884 APE67-dihe-in -75.6378, 0.4646 -57.8192, -29.8755 APE12-dist-na 17.219 APE11-dist-na 19.703 APE10-dist-na 16.309 APE9-dist-out 11.24 None None None XRAY 1.81 0.178 0.215 B 310 286 20 0 0 7 [[478, 756]] 1.0 9vlj Homo sapiens TYR_FGFR1_HUMAN TYR 2.2e-104 354.4 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 9VLMA P21802 465 763 821.0 A1ESP:801 Type1 Inactive DFGin 5.102 13.624 BLAplus DFGAsp-rot-out -113.8738, 164.4131 61.8369, 25.9143 287.6864, -4.7727 -76.2414, -15.1751 56.6026, 88.5713 -104.9967, 9.8607 in-in in 8.238 Saltbr-in 3.334 HRD-in -72.5637, -49.4303 74.5853, -6.4272 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -150.2825, 156.7344 APE9-dihe-in -118.9012, 103.5063 APE8-dihe-out -45.5188, -35.2148 APE8-rot-na 332.6996 APE67-dihe-in -71.8118, -9.6131 -46.6328, -35.6902 APE12-dist-na 14.669 APE11-dist-na 18.736 APE10-dist-na 16.645 APE9-dist-out 10.902 None None None XRAY 2.26 0.209 0.254 A 303 278 21 0 0 12 [[481, 759]] 1.0 9vlm Homo sapiens TYR_FGFR2_HUMAN TYR 2.3e-104 354.3 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9VLMB P21802 465 763 821.0 A1ESP:801 Type1 Inactive DFGin 5.016 13.586 BLAplus DFGAsp-rot-out -113.2535, 167.4941 63.9716, 27.2042 271.1868, 47.8752 -84.2123, -19.3285 61.5314, 87.6792 -99.6038, 23.5029 in-in in 8.284 Saltbr-in 2.775 HRD-in -87.1597, -52.1506 75.5177, -0.0448 in-out-none SNCion out-none ActLoopNT-out 7.333 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -73.2396 APE8-dihe-in -86.5555, 73.4116 APE8-rot-na 28.8959 APE67-dihe-in -71.0526, -10.1419 -47.7361, -46.61 APE12-dist-na 14.942 APE11-dist-na 18.363 APE10-dist-na 999.0 APE9-dist-in 7.856 None None None XRAY 2.26 0.209 0.254 B 303 280 19 0 0 12 [[481, 759]] 1.0 9vlm Homo sapiens TYR_FGFR2_HUMAN TYR 2.3e-104 354.3 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

Ligand: A1ESP

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name