Ligand: A1EOH

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 9U7EA
DFGin BLAplus 2 50.0% 9U7GA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR FGFR1 FGFR1_HUMAN 9U7GA 1.66 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaao A1EOH Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9U7GB 1.66 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-out TYR APEdihe_nnoai APEdist_aaao A1EOH Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 9U7EA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaai A1EOH Type1 467 - 763 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U7EB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaai A1EOH Type1 467 - 763 0 None None Fibroblast growth factor receptor 2

Ligand: A1EOH

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 9U7EA
DFGin BLAplus 2 50.0% 9U7GA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR FGFR1 FGFR1_HUMAN 9U7GA 1.66 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaao A1EOH Type1 458 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 9U7GB 1.66 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-out TYR APEdihe_nnoai APEdist_aaao A1EOH Type1 458 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 9U7EA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaai A1EOH Type1 467 - 763 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 9U7EB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaai A1EOH Type1 467 - 763 0 None None Fibroblast growth factor receptor 2 Homo sapiens

Ligand: A1EOH

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism