Ligand: A1AV2

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 5 100.0% 9CD5B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 9CD5A P11362 465 764 822.0 A1AV2:903 Type1 Inactive DFGin 5.1092 13.0413 BLAplus -119.69, 171.16 42.37, 48.64 -93.51, -18.78 55.6, 81.67 -108.27, 19.83 in-in in 7.6418 Saltbr-in 3.4001 HRD-in -70.51, -58.43 92.5, -15.84 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -123.63, 147.65 APE9-dihe-in -93.38, 113.67 APE8-dihe-out -55.42, -20.8 APE8-rot-na 334.26 APE67-dihe-in -78.47, -7.11 -58.87, -20.29 APE12-dist-na 21.398 APE11-dist-na 21.2383 APE10-dist-na 19.5201 APE9-dist-out 11.6083 C488A,C584S None None XRAY 2.939 0.215 0.263 A 308.0 281.0 19 30 24 6 [[478, 756]] 1.0 9cd5 TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9CD5B P11362 460 764 822.0 A1AV2:902 Type1 Inactive DFGin 5.1115 12.7756 BLAplus -119.68, 169.96 44.78, 47.92 -93.2, -18.16 54.47, 80.79 -103.83, 15.64 in-in in 7.5897 Saltbr-in 3.2422 HRD-in -70.44, -57.93 92.25, -15.3 in-out-out SNCioo out-out ActLoopNT-out 7.9791 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -124.57, 148.55 APE9-dihe-in -93.36, 113.84 APE8-dihe-out -53.62, -20.73 APE8-rot-na 332.43 APE67-dihe-in -77.99, -7.05 -59.24, -19.94 APE12-dist-na 21.0098 APE11-dist-na 20.993 APE10-dist-na 19.181 APE9-dist-out 11.5839 C488A,C584S None None XRAY 2.939 0.215 0.263 B 308.0 289.0 16 30 28 2 [[478, 756]] 1.0 9cd5 TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR3 FGFR3_HUMAN 9CD7A P22607 451 755 806.0 A1AV2:801 Type1 Inactive DFGin 5.0186 12.7277 BLAplus -114.49, 161.16 51.06, 50.03 -90.62, -20.91 50.11, 84.08 -82.82, 141.47 in-in in 7.0948 Saltbr-in 2.5832 HRD-in -75.51, -51.62 85.64, -15.78 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 85.15 APE8-dihe-out -64.87, -3.22 APE8-rot-na 28.88 APE67-dihe-in -77.21, -9.06 -69.64, -25.05 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.3457 C482A,C582S,K650E None None XRAY 2.53 0.23 0.267 A 312.0 276.0 29 30 13 17 [[472, 750]] 1.0 9cd7 TYR_FGFR3_HUMAN TYR 2e-104 354.4 1.0 260.0 260.0 634 635 636 638 640 508 525 529 614 616 615 617.0 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7B P22607 458 755 806.0 A1AV2:801 Type1 Inactive DFGin 5.0653 12.8593 BLAplus -114.57, 159.12 51.43, 51.5 -92.22, -19.36 49.89, 84.09 -76.73, -39.85 in-in in 7.4133 Saltbr-in 2.5967 HRD-in -74.94, -51.38 85.94, -16.13 in-out-out SNCioo out-out ActLoopNT-out 7.5988 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 48.12 APE8-dihe-out -65.12, -2.8 APE8-rot-na 29.36 APE67-dihe-in -77.72, -8.63 -66.93, -28.5 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.2175 C482A,C582S,K650E None None XRAY 2.53 0.23 0.267 B 312.0 278.0 20 30 24 6 [[472, 750]] 1.0 9cd7 TYR_FGFR3_HUMAN TYR 2e-104 354.4 1.0 260.0 260.0 634 635 636 638 640 508 525 529 614 616 615 617.0 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7C P22607 458 755 806.0 A1AV2:801 Type1 Inactive DFGin 5.0552 12.9174 BLAplus -113.11, 157.29 52.27, 52.26 -91.9, -19.06 50.44, 84.08 -76.91, -39.15 in-in in 7.4207 Saltbr-in 2.6017 HRD-in -75.28, -51.41 85.96, -15.25 in-out-out SNCioo out-out ActLoopNT-out 7.7116 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 98.75 APE8-dihe-out -72.0, 23.1 APE8-rot-na 34.26 APE67-dihe-in -76.94, -9.16 -66.89, -26.41 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 10.796 C482A,C582S,K650E None None XRAY 2.53 0.23 0.267 C 312.0 278.0 20 30 24 6 [[472, 750]] 1.0 9cd7 TYR_FGFR3_HUMAN TYR 2e-104 354.4 1.0 260.0 260.0 634 635 636 638 640 508 525 529 614 616 615 617.0 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

Ligand: A1AV2

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 5 100.0% 9CD5B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 9CD5A P11362 465 764 822.0 A1AV2:903 Type1 Inactive DFGin 5.1092 13.0413 BLAplus -119.69, 171.16 42.37, 48.64 -93.51, -18.78 55.6, 81.67 -108.27, 19.83 in-in in 7.6418 Saltbr-in 3.4001 HRD-in -70.51, -58.43 92.5, -15.84 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -123.63, 147.65 APE9-dihe-in -93.38, 113.67 APE8-dihe-out -55.42, -20.8 APE8-rot-na 334.26 APE67-dihe-in -78.47, -7.11 -58.87, -20.29 APE12-dist-na 21.398 APE11-dist-na 21.2383 APE10-dist-na 19.5201 APE9-dist-out 11.6083 C488A,C584S None None XRAY 2.939 0.215 0.263 A 308.0 281.0 19 30 24 6 [[478, 756]] 1.0 9cd5 Homo sapiens TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9CD5B P11362 460 764 822.0 A1AV2:902 Type1 Inactive DFGin 5.1115 12.7756 BLAplus -119.68, 169.96 44.78, 47.92 -93.2, -18.16 54.47, 80.79 -103.83, 15.64 in-in in 7.5897 Saltbr-in 3.2422 HRD-in -70.44, -57.93 92.25, -15.3 in-out-out SNCioo out-out ActLoopNT-out 7.9791 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -124.57, 148.55 APE9-dihe-in -93.36, 113.84 APE8-dihe-out -53.62, -20.73 APE8-rot-na 332.43 APE67-dihe-in -77.99, -7.05 -59.24, -19.94 APE12-dist-na 21.0098 APE11-dist-na 20.993 APE10-dist-na 19.181 APE9-dist-out 11.5839 C488A,C584S None None XRAY 2.939 0.215 0.263 B 308.0 289.0 16 30 28 2 [[478, 756]] 1.0 9cd5 Homo sapiens TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR3 FGFR3_HUMAN 9CD7A P22607 451 755 806.0 A1AV2:801 Type1 Inactive DFGin 5.0186 12.7277 BLAplus -114.49, 161.16 51.06, 50.03 -90.62, -20.91 50.11, 84.08 -82.82, 141.47 in-in in 7.0948 Saltbr-in 2.5832 HRD-in -75.51, -51.62 85.64, -15.78 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 85.15 APE8-dihe-out -64.87, -3.22 APE8-rot-na 28.88 APE67-dihe-in -77.21, -9.06 -69.64, -25.05 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.3457 C482A,C582S,K650E None None XRAY 2.53 0.23 0.267 A 312.0 276.0 29 30 13 17 [[472, 750]] 1.0 9cd7 Homo sapiens TYR_FGFR3_HUMAN TYR 2e-104 354.4 1.0 260.0 260.0 634 635 636 638 640 508 525 529 614 616 615 617.0 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7B P22607 458 755 806.0 A1AV2:801 Type1 Inactive DFGin 5.0653 12.8593 BLAplus -114.57, 159.12 51.43, 51.5 -92.22, -19.36 49.89, 84.09 -76.73, -39.85 in-in in 7.4133 Saltbr-in 2.5967 HRD-in -74.94, -51.38 85.94, -16.13 in-out-out SNCioo out-out ActLoopNT-out 7.5988 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 48.12 APE8-dihe-out -65.12, -2.8 APE8-rot-na 29.36 APE67-dihe-in -77.72, -8.63 -66.93, -28.5 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.2175 C482A,C582S,K650E None None XRAY 2.53 0.23 0.267 B 312.0 278.0 20 30 24 6 [[472, 750]] 1.0 9cd7 Homo sapiens TYR_FGFR3_HUMAN TYR 2e-104 354.4 1.0 260.0 260.0 634 635 636 638 640 508 525 529 614 616 615 617.0 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7C P22607 458 755 806.0 A1AV2:801 Type1 Inactive DFGin 5.0552 12.9174 BLAplus -113.11, 157.29 52.27, 52.26 -91.9, -19.06 50.44, 84.08 -76.91, -39.15 in-in in 7.4207 Saltbr-in 2.6017 HRD-in -75.28, -51.41 85.96, -15.25 in-out-out SNCioo out-out ActLoopNT-out 7.7116 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 98.75 APE8-dihe-out -72.0, 23.1 APE8-rot-na 34.26 APE67-dihe-in -76.94, -9.16 -66.89, -26.41 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 10.796 C482A,C582S,K650E None None XRAY 2.53 0.23 0.267 C 312.0 278.0 20 30 24 6 [[472, 750]] 1.0 9cd7 Homo sapiens TYR_FGFR3_HUMAN TYR 2e-104 354.4 1.0 260.0 260.0 634 635 636 638 640 508 525 529 614 616 615 617.0 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

Ligand: A1AV2

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name