Ligand: 9OO

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 8PQCB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR KIT KIT_HUMAN 8PQCA 1.77 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9OO Type1 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQCB 1.77 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9OO Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR PDGFRA PGFRA_HUMAN 8PQIA 2.6 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9OO Type1 567 - 969 0 None T674I Platelet-derived growth factor receptor alpha

Ligand: 9OO

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 8PQCB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR KIT KIT_HUMAN 8PQCA 1.77 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9OO Type1 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8PQCB 1.77 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9OO Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR PDGFRA PGFRA_HUMAN 8PQIA 2.6 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9OO Type1 567 - 969 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens

Ligand: 9OO

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism