Ligand: 9OO

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 8PQCB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQCA P10721 566 932 976.0 9OO:61001 Type1 Active DFGin 7.3203 13.7282 BLAminus -124.52, 177.4 59.32, 88.07 -98.4, 24.69 287.2, 70.41 -61.62, -29.61 in-in in 7.8146 Saltbr-in 2.7673 HRD-in -93.83, -42.0 73.11, -0.37 in-in-in SNCiii in-in ActLoopNT-in 2.888 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.91, 142.75 APE9-dihe-in -125.5, 151.35 APE8-dihe-in -83.13, 70.57 APE8-rot-na 37.57 APE67-dihe-in -73.25, -7.87 -53.76, -43.02 APE12-dist-na 14.0422 APE11-dist-na 9.7008 APE10-dist-na 13.0233 APE9-dist-in 7.718 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.77 0.183 0.206 A 327.0 287.0 2 30 28 2 [[589, 926]] 1.0 8pqc TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQCB P10721 566 931 976.0 9OO:61001 Type1 Active DFGin 7.283 13.8349 BLAminus -128.31, 173.51 60.11, 89.0 -97.68, 23.86 286.68, 71.19 -63.1, -28.82 in-in in 7.9711 Saltbr-in 2.8275 HRD-in -94.17, -44.79 74.42, -0.63 in-in-in SNCiii in-in ActLoopNT-in 2.9803 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.29, 141.63 APE9-dihe-in -125.35, 153.08 APE8-dihe-in -84.91, 76.41 APE8-rot-na 34.61 APE67-dihe-in -73.13, -6.88 -58.59, -41.47 APE12-dist-na 14.0973 APE11-dist-na 9.7391 APE10-dist-na 13.1187 APE9-dist-in 7.6922 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.77 0.183 0.206 B 327.0 287.0 1 30 29 1 [[589, 926]] 1.0 8pqc TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR PDGFRA PGFRA_HUMAN 8PQIA P16234 567 969 1089.0 9OO:1001 Type1 Active DFGin 6.9059 13.5927 BLAminus -132.24, 178.87 62.52, 88.22 -103.25, 28.49 291.7, 71.46 -68.1, -30.59 in-in in 7.9933 Saltbr-in 2.898 HRD-in -71.63, -43.38 66.22, 2.62 in-in-in SNCiii in-in ActLoopNT-in 2.8201 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -98.65, 130.26 APE9-dihe-in -117.66, 147.18 APE8-dihe-in -84.02, 76.87 APE8-rot-na 33.16 APE67-dihe-in -69.02, -9.85 -66.15, -32.32 APE12-dist-na 999.0 APE11-dist-na 9.4755 APE10-dist-na 11.4786 APE9-dist-in 7.1354 T674I None None XRAY 2.6 0.232 0.254 A 352.0 299.0 32 30 20 10 [[593, 952]] 1.0 8pqi TYR_PDGFRA_HUMAN TYR 1.8e-106 361.4 1.0 260.0 260.0 835 836 837 839 841 627 644 648 815 817 816 818.0 877 865 860 859 858 857 856 855 854 675 Platelet-derived growth factor receptor alpha

Ligand: 9OO

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 8PQCB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQCA P10721 566 932 976.0 9OO:61001 Type1 Active DFGin 7.3203 13.7282 BLAminus -124.52, 177.4 59.32, 88.07 -98.4, 24.69 287.2, 70.41 -61.62, -29.61 in-in in 7.8146 Saltbr-in 2.7673 HRD-in -93.83, -42.0 73.11, -0.37 in-in-in SNCiii in-in ActLoopNT-in 2.888 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.91, 142.75 APE9-dihe-in -125.5, 151.35 APE8-dihe-in -83.13, 70.57 APE8-rot-na 37.57 APE67-dihe-in -73.25, -7.87 -53.76, -43.02 APE12-dist-na 14.0422 APE11-dist-na 9.7008 APE10-dist-na 13.0233 APE9-dist-in 7.718 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.77 0.183 0.206 A 327.0 287.0 2 30 28 2 [[589, 926]] 1.0 8pqc Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQCB P10721 566 931 976.0 9OO:61001 Type1 Active DFGin 7.283 13.8349 BLAminus -128.31, 173.51 60.11, 89.0 -97.68, 23.86 286.68, 71.19 -63.1, -28.82 in-in in 7.9711 Saltbr-in 2.8275 HRD-in -94.17, -44.79 74.42, -0.63 in-in-in SNCiii in-in ActLoopNT-in 2.9803 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.29, 141.63 APE9-dihe-in -125.35, 153.08 APE8-dihe-in -84.91, 76.41 APE8-rot-na 34.61 APE67-dihe-in -73.13, -6.88 -58.59, -41.47 APE12-dist-na 14.0973 APE11-dist-na 9.7391 APE10-dist-na 13.1187 APE9-dist-in 7.6922 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.77 0.183 0.206 B 327.0 287.0 1 30 29 1 [[589, 926]] 1.0 8pqc Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR PDGFRA PGFRA_HUMAN 8PQIA P16234 567 969 1089.0 9OO:1001 Type1 Active DFGin 6.9059 13.5927 BLAminus -132.24, 178.87 62.52, 88.22 -103.25, 28.49 291.7, 71.46 -68.1, -30.59 in-in in 7.9933 Saltbr-in 2.898 HRD-in -71.63, -43.38 66.22, 2.62 in-in-in SNCiii in-in ActLoopNT-in 2.8201 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -98.65, 130.26 APE9-dihe-in -117.66, 147.18 APE8-dihe-in -84.02, 76.87 APE8-rot-na 33.16 APE67-dihe-in -69.02, -9.85 -66.15, -32.32 APE12-dist-na 999.0 APE11-dist-na 9.4755 APE10-dist-na 11.4786 APE9-dist-in 7.1354 T674I None None XRAY 2.6 0.232 0.254 A 352.0 299.0 32 30 20 10 [[593, 952]] 1.0 8pqi Homo sapiens TYR_PDGFRA_HUMAN TYR 1.8e-106 361.4 1.0 260.0 260.0 835 836 837 839 841 627 644 648 815 817 816 818.0 877 865 860 859 858 857 856 855 854 675 Platelet-derived growth factor receptor alpha

Ligand: 9OO

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name