Ligand: 8PR

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 3V5WA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC GRK2 ARBK1_HUMAN 3V5WA 2.07 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8PR Type1 30 - 668 0 None None Beta-adrenergic receptor kinase 1

Ligand: 8PR

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 3V5WA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC GRK1 GRK1_BOVIN 4L9IA 2.32 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8PR Type1 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 4L9IB 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8PR Type1 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK2 ARBK1_HUMAN 3V5WA 2.07 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8PR Type1 30 - 668 0 None None Beta-adrenergic receptor kinase 1 Homo sapiens

Ligand: 8PR

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4L9IA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC GRK1 GRK1_BOVIN 4L9IA 2.32 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8PR Type1 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 4L9IB 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8PR Type1 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus