Ligand: 7YS

Total number of chains: 6
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 4 66.7% 5U6CA
DFGin BLAminus 2 33.3% 5U6BB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR AXL UFO_HUMAN 5U6BB 2.84 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO
TYR AXL UFO_HUMAN 5U6BD 2.84 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO
TYR AXL UFO_HUMAN 5U6BA 2.84 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO
TYR AXL UFO_HUMAN 5U6BC 2.84 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO
TYR MERTK MERTK_HUMAN 5U6CA 2.1 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 572 - 864 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5U6CB 2.1 Inactive DFGin‑None out-out none-out TYR APEdihe_nniai APEdist_aaao 7YS Type1 575 - 862 0 None None Tyrosine-protein kinase Mer

Ligand: 7YS

Total number of chains: 6
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 4 66.7% 5U6CA
DFGin BLAminus 2 33.3% 5U6BB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR AXL UFO_HUMAN 5U6BB 2.84 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
TYR AXL UFO_HUMAN 5U6BD 2.84 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
TYR AXL UFO_HUMAN 5U6BA 2.84 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
TYR AXL UFO_HUMAN 5U6BC 2.84 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
TYR MERTK MERTK_HUMAN 5U6CA 2.1 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 572 - 864 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 5U6CB 2.1 Inactive DFGin‑None out-out none-out TYR APEdihe_nniai APEdist_aaao 7YS Type1 575 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens

Ligand: 7YS

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism