TYR_AXL (Tyrosine-protein kinase receptor UFO)

Total number of chains: 6
Active chains: 4
Uniprot: UFO_HUMAN
Kinase Domain Residues: 536 - 805
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% AF-P30530-K1A
DFGin None 2 33.3% 5U6BA

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P30530-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 528 - 813 0 None None Tyrosine-protein kinase receptor UFO
AF-P30530-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 528 - 813 0 None None Tyrosine-protein kinase receptor UFO
5U6BB 2.84 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO
5U6BD 2.84 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO
5U6BA 2.84 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO
5U6BC 2.84 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO

TYR_AXL (Tyrosine-protein kinase receptor UFO)

Total number of chains: 6
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% AF-P30530-K1A
DFGin None 2 33.3% 5U6BA

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
UFO_HUMAN AF-P30530-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 528 - 813 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
UFO_HUMAN AF-P30530-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 528 - 813 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
UFO_HUMAN 5U6BB 2.84 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
UFO_HUMAN 5U6BD 2.84 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
UFO_HUMAN 5U6BA 2.84 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens
UFO_HUMAN 5U6BC 2.84 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO Homo sapiens

TYR_AXL (Tyrosine-protein kinase receptor UFO)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism