Ligand: 7XR

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 2 66.7% 5X2CB
DFGin BLAminus 1 33.3% 5X27A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 5X27A 2.952 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 7XR Type1 697 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2CA 2.05 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao 7XR Type1 700 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2CB 2.05 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao 7XR Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor

Ligand: 7XR

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 2 66.7% 5X2CB
DFGin BLAminus 1 33.3% 5X27A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 5X27A 2.952 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 7XR Type1 697 - 1020 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2CA 2.05 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao 7XR Type1 700 - 1015 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2CB 2.05 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao 7XR Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: 7XR

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism